Question 1

Similarities between organ-specific and organ-nonspecific disorders include the finding of a decreased immunoglobulin concentration in serum.

Accepted Answer

A) True 
 B)False

Question 2

Match the term with the appropriate definition.
-Anti-parietal cell antibody

Accepted Answer

A) Measures antibody to nuclear antigens 
B) Produces a characteristic granular cytoplasmic staining pattern to cytoplasmic constituents of granulocytes 
C) An antibody to a basic nonhistone nuclear protein 
D) Found in about 80% of patients with pernicious anemia 
A) Measures antibody to nuclear antigens 
B) Produces a characteristic granular cytoplasmic staining pattern to cytoplasmic constituents of granulocytes 
C) An antibody to a basic nonhistone nuclear protein 
D) Found in about 80% of patients with pernicious anemia

Question 3

Antimyelin antibody is associated with:

Accepted Answer

A)  rheumatoid arthritis (R
A) . 
B)  multiple sclerosis (MS). 
C)  pernicious anemia (P
A) . 
D)  systemic lupus erythematosus (SL
E) . 
A)  rheumatoid arthritis (R
A) . 
B)  multiple sclerosis (MS). 
C)  pernicious anemia (P
A) . 
D)  systemic lupus erythematosus (SL
E) .

Question 4

Antibodies demonstrated in pernicious anemia (PA)include:

Accepted Answer

A)  anti-intrinsic factor. 
B)  antiparietal. 
C)  antiinsulin. 
D)  both a and b 
A)  anti-intrinsic factor. 
B)  antiparietal. 
C)  antiinsulin. 
D)  both a and b

Question 5

MATCHING
Match the statements with the correct type of disorder (a or b).

-Tendency to develop lymphoreticular neoplasia.

Accepted Answer

A) Organ-specific 
B) Organ- nonspecific 
A) Organ-specific 
B) Organ- nonspecific

Question 6

Anti-DNA antibody is associated with:

Accepted Answer

A)  rheumatoid arthritis (R
A) . 
B)  multiple sclerosis (MS). 
C)  pernicious anemia (P
A) . 
D)  systemic lupus erythematosus (SL
E) . 
A)  rheumatoid arthritis (R
A) . 
B)  multiple sclerosis (MS). 
C)  pernicious anemia (P
A) . 
D)  systemic lupus erythematosus (SL
E) .

Question 7

Similarities between organ-specific and organ-nonspecific disorders include the fact that the disease process is not always progressive;exacerbations and remissions occur.

Accepted Answer

A) True 
 B)False

Question 8

MATCHING
Match the statements with the correct type of disorder (a or b).

-Familial tendency to develop connective tissue disease.

Accepted Answer

A) Organ-specific 
B) Organ- nonspecific 
A) Organ-specific 
B) Organ- nonspecific

Question 9

MATCHING
Match the statements with the correct type of disorder (a or b).

-Tendency to develop cancer in the organ.

Accepted Answer

A) Organ-specific 
B) Organ- nonspecific 
A) Organ-specific 
B) Organ- nonspecific

Question 10

An individual may develop an autoimmune response to:

Accepted Answer

A)  antigens that do not normally circulate in the blood. 
B)  altered antigens. 
C)  loss of immunoregulatory function by lymphocyte subsets. 
D)  all of the above. 
A)  antigens that do not normally circulate in the blood. 
B)  altered antigens. 
C)  loss of immunoregulatory function by lymphocyte subsets. 
D)  all of the above.

Exam 28: Autoimmune Disorders

Similarities between organ-specific and organ-nonspecific disorders include the finding of a decreased immunoglobulin concentration in serum.

Match the term with the appropriate definition. -Anti-parietal cell antibody

Antimyelin antibody is associated with:

Antibodies demonstrated in pernicious anemia (PA)include:

MATCHING Match the statements with the correct type of disorder (a or b). -Tendency to develop lymphoreticular neoplasia.

Anti-DNA antibody is associated with:

Similarities between organ-specific and organ-nonspecific disorders include the fact that the disease process is not always progressive;exacerbations and remissions occur.

MATCHING Match the statements with the correct type of disorder (a or b). -Familial tendency to develop connective tissue disease.

MATCHING Match the statements with the correct type of disorder (a or b). -Tendency to develop cancer in the organ.

An individual may develop an autoimmune response to:

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Point-Of-Care Testing

Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Automated Procedures

Molecular Techniques

The Immune Response in Infectious Diseases

A Primer on Vaccines

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Acquired Immunodeficiency Syndrome

Hypersensitivity Reactions

Immunoproliferative Disorders

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Solid Organ Transplantation

Bone Marrow Transplantation

Tumor Immunology

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