Exam 8: Chromosomes and Human Genetics

The sex of a human child is determined by the

The karyotype shown below is from a(n)

Karen and Jared produce three healthy children.The first child is a boy (Daniel)and the next two are girls (Leslie and Alice).Daniel grows up,marries Dana,and they have two children.Their first child is a healthy baby boy and the second is a little girl who is diagnosed with phenylketonuria (PKU).Draw this family's pedigree.

Match each correct statement to the set of alleles listed below. -male affected by recessive sex-linked disease

Describe the possible genotypes and phenotypes (include probabilities)of offspring from a cross between a female heterozygous for the X-linked allele that produces Wiskott-Aldrich syndrome (WAS)and a male who does not have WAS.

During cell division a piece of a chromosome breaks off and reattaches to the same chromosome,but the piece is now in reverse order.How would this abnormality affect the chromosome?

Among children with parents who are both carriers of Tay-Sachs,an autosomal recessive disorder,chances are that

A karyotype shows a chromosomal abnormality that does not change the length of any of the chromosomes.Which abnormality is indicated?

Match each correct statement to the set of alleles listed below. -heterozygous for an autosomal gene

A parent who is a carrier for the recessive autosomal disorder B has the genotype ________.

During routine genetic testing before the 2014 NBA Draft former Baylor Bears' basketball center Isaiah Austin was diagnosed with Marfan syndrome.This genetic condition results in connective tissue problems for the individual.One of the more life-threatening features of this condition is aortic enlargement,which can leave the aorta susceptible to rupture.In 75 percent of the cases,the allele is inherited from one parent; in the other 25 percent of the cases,a new mutation has occurred.Explain whether this condition is likely an autosomal disorder (recessive or dominant)or an X-linked disorder; support your answer with information from the infographic shown below.

Why are X-linked recessive genetic disorders more commonly seen in males?

Most inherited human genetic disorders are inherited as ________ alleles.

Which of the following must be true for a woman who is heterozygous for a given gene?

A man with a translocation in a chromosome that does not affect gene function may not realize he has a translocation until he attempts to have a child.Explain how a translocation that does not affect the individual may become problematic during reproduction.

A disease caused by an inherited mutation is a ________ disorder.

If two parents are heterozygous for an autosomal recessive disease,

Which of the following statements about homologous chromosomes is true?

A ________ is a chart that shows genetic relationships within a family over several generations.

Humans have ________ pairs of homologous chromosomes.