Exam 8: Chromosomes and Human Genetics

Wiskott-Aldrich syndrome (WAS)is a sex-linked recessive blood disorder that results when an individual does not have a functional WAS gene.Explain where a functional WAS gene can be isolated and how genetic engineering could be used to treat a patient who has WAS.

Which of the following genetic changes would NOT be passed from parent to child?

In humans,the "master sex switch" that determines whether an embryo will become a male is the

The chromosome on the left of the figure below is chromosome number 5 from the father of a newborn child with cri du chat syndrome.The chromosome on the right is paternal chromosome number 5 in the child.What type of chromosomal abnormality has caused this syndrome in the child? Explain your answer.

The pedigree shown below diagrams an X-linked gene.The individual indicated is ________ for the gene.

In humans,X-linked genetic diseases

If a female who carries the X-linked recessive gene for hemophilia mates with a male who does not have hemophilia,what is the chance that their daughter will be a carrier of the gene?

X-linked disorders more commonly affect males than females because males have only one ________ chromosome.

Both members of a couple are carriers for a recessive disease allele.If the couple has four children,which of the following statements must be true?

Match each correct statement to the set of alleles listed below. -female carrier of a sex-linked disease

If an individual has two alleles at a given locus that are different,the individual is said to be ________ for the gene.

Does the pedigree shown below most likely represent a condition that is autosomal recessive,dominant,or sex-linked? Explain your reasoning.

Two copies of the same gene on a single chromosome would indicate a(n)________ had occurred.

Match each correct statement to the set of alleles listed below. -recessive homozygous for an autosomal gene

An allele that appears more frequently in males is MOST likely

Except for the sex chromosomes,all the chromosomes shown in a karyotype are numbered and are called ________.

On chromosomes within an individual,there are ________ alleles for a given gene found on ________ chromosomes.

An X-linked carrier is a female individual with a ________ genotype,on her X chromosomes,who does not express the recessive trait but can pass it along to offspring.

Which of the following would explain two chromosomes in an individual cell that contain some,but not all,of the same genes at the same loci?

Because an individual with an XX genotype is a female,is an individual with an XO (no second sex chromosome)a male?