Exam 66: Antiviral Therapy, Susceptibility Testing, and Prevention

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Match the virus with the appropriate antiviral agent. -Amantadine

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If a physician prescribes Tamiflu to a patient, the patient is most likely infected with which virus?

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D

Point mutations in the hemagglutination (HA)or neuraminidase (NA)genes during viral ribonucleoprotein (RNP)replication give rise to new strains.This mechanism is known as the antigenic:

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Which type of assay uses a variety of endpoint measurements to determine whether the virus is inhibited by the antiviral drug or is demonstrating drug resistance?

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In the 1920s, an instrument known as an "iron lung" was developed to fight breathing difficulties associated with which infection?

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Match the virus with the appropriate antiviral agent. -Lamivudine

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Match the virus with the appropriate antiviral agent. -Acyclovir

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MATCHING Match the assay with its function. -Inhibits viral plaque formation.

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When performing antiviral susceptibility testing, a standard inoculum must be used.If the inoculum quantity is too large, then the isolate will appear:

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At the end of the 2008-2009 influenza season, 100% influenza A H3N2 and the novel 2009 influenza A H1N1 were resistant to:

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The only virus that has been globally eradicated is:

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MATCHING Match the assay with its function. -Detects resistance genes.

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Match the virus with the appropriate antiviral agent. -Saquinavir

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MATCHING Match the assay with its function. -Viable cells take up neutral red dye.

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MATCHING Match the assay with its function. -Quantifies sequence variation.

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MATCHING Match the assay with its function. -Quantifies the amount of viruses infected in cells.

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Match the virus with the appropriate antiviral agent. -Ribavirin

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The recombinant virus assay (RVA)uses which type of amplification methodology?

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MATCHING Match the assay with its function. -Inhibits viral DNA synthesis.

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