Question 1

Which of the following is included in the model of electron transport?

Accepted Answer

A) protons driven into the matrix 
B) mobile coenzyme Q releasing electrons 
C) cyt c moving in the intermembrane space 
D) proton gradient reduced leading to loss of ATP production 
A) protons driven into the matrix 
B) mobile coenzyme Q releasing electrons 
C) cyt c moving in the intermembrane space 
D) proton gradient reduced leading to loss of ATP production

Question 2

Which of the following classifies the phosphorylation of ADP that is NADH-dependent?

Accepted Answer

A) oxidative 
B) electron 
C) proton-gradient 
D) substrate-level 
A) oxidative 
B) electron 
C) proton-gradient 
D) substrate-level

Question 3

Which of the following cytochromes,in the ferric form,do cyanide and azide bind tightly to?

Accepted Answer

A) cyt c 
B) cyt a3 
C) cyt bL 
D) cyt bH 
A) cyt c 
B) cyt a3 
C) cyt bL 
D) cyt bH

Question 4

Which of the following is a property of ATP synthase?

Accepted Answer

A) The F1 subunit is attached to the peripheral membrane protein F0. 
B) The ring of c subunits forms a rotor with respect to the alpha subunits. 
C) The F0 subunit is hydrophilic. 
D) Alpha-subunits have the catalytic site for ATP synthesis. 
A) The F1 subunit is attached to the peripheral membrane protein F0. 
B) The ring of c subunits forms a rotor with respect to the alpha subunits. 
C) The F0 subunit is hydrophilic. 
D) Alpha-subunits have the catalytic site for ATP synthesis.

Question 5

Which of the following is NOT a single-electron carrier?

Accepted Answer

A) UQH₂ 
B) cyt bL 
C) cyt bH 
D) cyt c1 
A) UQH₂ 
B) cyt bL 
C) cyt bH 
D) cyt c1

Question 6

Which of the following statements is a characteristic of the glycerophosphate shuttle?

Accepted Answer

A) It shuttles NADH across the mitochondrial membrane to yield 2.5 ATP/ADH. 
B) It shuttles "NADH electron equivalents" across the mitochondrial membrane to yield 1.5 ATP/NADH. 
C) It operates efficiently only when the [NADH] in the cytoplasm is higher than in the matrix. 
D) The molecule malate is a key component in the shuttle process. 
A) It shuttles NADH across the mitochondrial membrane to yield 2.5 ATP/ADH. 
B) It shuttles "NADH electron equivalents" across the mitochondrial membrane to yield 1.5 ATP/NADH. 
C) It operates efficiently only when the [NADH] in the cytoplasm is higher than in the matrix. 
D) The molecule malate is a key component in the shuttle process.

Question 7

Which of the following percentages of the proton gradient energy to synthesize and transport ATP to the cytosol is involved in ATP-ADP transport?

Accepted Answer

A) 10% 
B) 15% 
C) 25% 
D) 50% 
A) 10% 
B) 15% 
C) 25% 
D) 50%

Question 8

Which of the following is a characteristic of inner mitochondrial membranes?

Accepted Answer

A) They contain specific receptor proteins. 
B) They fold into cristae. 
C) They contain porin in high concentration. 
D) The membrane lipids have mostly saturated fatty acids. 
A) They contain specific receptor proteins. 
B) They fold into cristae. 
C) They contain porin in high concentration. 
D) The membrane lipids have mostly saturated fatty acids.

Question 9

Which of the following is NOT correct regarding the glycerophosphate shuttle?

Accepted Answer

A) Glycerol-3-phosphate is translocated across the inner mitochondrial membrane into the matrix. 
B) There are 2 distinct forms of glycerol-3-phosphate dehydrogenase in cells with this shuttle. 
C) It results in the net transfer of electrons to the electron-transport chain from NADH in the cytosol. 
D) Electrons derived from this shuttle enter the electron-transport chain at UQ. 
A) Glycerol-3-phosphate is translocated across the inner mitochondrial membrane into the matrix. 
B) There are 2 distinct forms of glycerol-3-phosphate dehydrogenase in cells with this shuttle. 
C) It results in the net transfer of electrons to the electron-transport chain from NADH in the cytosol. 
D) Electrons derived from this shuttle enter the electron-transport chain at UQ.

Question 10

Which of the following is an inhibitor of Complex IV?

Accepted Answer

A) rotenone 
B) oligomycin 
C) antimycin 
D) cyanide 
A) rotenone 
B) oligomycin 
C) antimycin 
D) cyanide

Question 11

Which of the following complexes does NOT translocate protons in the inner mitochondrial membrane?

Accepted Answer

A) Complex I 
B) Complex II 
C) Complex III 
D) Complex IV 
A) Complex I 
B) Complex II 
C) Complex III 
D) Complex IV

Question 12

In which of the following tissues does thermogenin (UCPI)create a passive proton channel through which protons flow from the cytosol to the mitochondrial matrix?

Accepted Answer

A) myelin 
B) brown adipose 
C) nerve 
D) cardiac 
A) myelin 
B) brown adipose 
C) nerve 
D) cardiac

Question 13

Which of the following defines the P/O ratio?

Accepted Answer

A) Pi uptake per oxygen atom by mitochondria 
B) molecules of phosphate released from ATP per oxygen utilized by muscle tissue 
C) ratio of atoms of phosphorus to oxygen in phosphate (Pi) 
D) molecules of ATP formed per 2 electrons flowing through electron-transport chain 
A) Pi uptake per oxygen atom by mitochondria 
B) molecules of phosphate released from ATP per oxygen utilized by muscle tissue 
C) ratio of atoms of phosphorus to oxygen in phosphate (Pi) 
D) molecules of ATP formed per 2 electrons flowing through electron-transport chain

Question 14

Which of the following is a characteristic of the malate-aspartate?

Accepted Answer

A) Electrons of cytosolic NADH are translocated to mitochondrial NADH. 
B) OAA is translocated to the inner mitochondrial membrane. 
C) There is only one malate dehydrogenase enzyme. 
D) The reactions are irreversible. 
A) Electrons of cytosolic NADH are translocated to mitochondrial NADH. 
B) OAA is translocated to the inner mitochondrial membrane. 
C) There is only one malate dehydrogenase enzyme. 
D) The reactions are irreversible.

Question 15

Which of the following cytochromes receives the electron transferred from UQH₂ to the Rieske protein?

Accepted Answer

A) cyt c 
B) cyt bH 
C) cyt bL 
D) cyt c1 
A) cyt c 
B) cyt bH 
C) cyt bL 
D) cyt c1

Question 16

Which of the following complexes will be affected if rotenone is added?

Accepted Answer

A) Complex I 
B) Complex II 
C) Complex III 
D) Complex IV 
A) Complex I 
B) Complex II 
C) Complex III 
D) Complex IV

Exam 19: Electron Transport and Oxidative Phosphorylation

Which of the following is included in the model of electron transport?

Which of the following classifies the phosphorylation of ADP that is NADH-dependent?

Which of the following cytochromes,in the ferric form,do cyanide and azide bind tightly to?

Which of the following is a property of ATP synthase?

Which of the following is NOT a single-electron carrier?

Which of the following statements is a characteristic of the glycerophosphate shuttle?

Which of the following percentages of the proton gradient energy to synthesize and transport ATP to the cytosol is involved in ATP-ADP transport?

Which of the following is a characteristic of inner mitochondrial membranes?

Which of the following is NOT correct regarding the glycerophosphate shuttle?

Which of the following is an inhibitor of Complex IV?

Which of the following complexes does NOT translocate protons in the inner mitochondrial membrane?

In which of the following tissues does thermogenin (UCPI)create a passive proton channel through which protons flow from the cytosol to the mitochondrial matrix?

Which of the following defines the P/O ratio?

Which of the following is a characteristic of the malate-aspartate?

Which of the following cytochromes receives the electron transferred from UQH₂ to the Rieske protein?

Which of the following complexes will be affected if rotenone is added?

The Facts of Life: Chemistry Is the Logic of Biological Phenomena

Water: the Medium of Life

Thermodynamics of Biological Systems

Amino Acids

Proteins: Their Primary Structure and Biological Functions

Proteins: Secondary, tertiary, and Quaternary Structure

Carbohydrates and the Glycoconjugates of Cell Surfaces

Lipids

Lipid Biosynthesis

Membranes and Membrane Transport

The Reception and Transmission of Extracellular Information

Enzymes Kinetics and Specificity

Mechanisms of Enzyme Action

Enzyme Regulation

Molecular Motors

Nutrition and the Organization of Metabolism

Glycolysis

The Tricarboxylic Acid Cycle

Photosynthesis

Gluconeogenesis, glycogen Metabolism, and the Pentose Phosphate Pathway

Fatty Acid Catabolism

Nitrogen Acquisition and Amino Acid Metabolism

Nucleotides and Nucleic Acids

Structure of Nucleic Acids

Synthesis and Degradation of Nucleotides

Recombinant Dna: Cloning and Creation of Chimeric Genes

DNA Metabolism: Replication, recombination, and Repair

Transcription and the Regulation of Gene Expression

Protein Synthesis

Post-Transcriptional Regulation of Gene Expression

Completing the Protein Life Cycle: Folding, processing, and Degradation

Metabolic Integration and Organ Specialization

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