Exam 9: Transcriptional Regulation and Epigenetics
Exam 1: An Overview of Cells and Cell Research124 Questions
Exam 2: Molecules and Membranes133 Questions
Exam 3: Bioenergetics and Metabolism138 Questions
Exam 4: Fundamentals of Molecular Biology117 Questions
Exam 5: Genomics, Proteomics, and Systems Biology108 Questions
Exam 6: Genes and Genomes101 Questions
Exam 7: Replication, Maintenance, and Rearrangements of Genomic Dna103 Questions
Exam 8: RNA Synthesis and Processing104 Questions
Exam 9: Transcriptional Regulation and Epigenetics115 Questions
Exam 10: Protein Synthesis, Processing, and Regulation98 Questions
Exam 11: The Nucleus128 Questions
Exam 12: Protein Sorting and Transport110 Questions
Exam 13: Mitochondria, Chloroplasts, and Peroxisomes106 Questions
Exam 14: The Cytoskeleton and Cell Movement106 Questions
Exam 15: The Plasma Membrane109 Questions
Exam 16: Cell Walls, the Extracellular Matrix, and Cell Interactions101 Questions
Exam 17: Cell Signaling114 Questions
Exam 18: The Cell Cycle101 Questions
Exam 19: Cell Death and Cell Renewal107 Questions
Exam 20: Cancer102 Questions
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Polycomb proteins are important in repressing gene transcription during development and differentiation. They act by _______ lysine residues in histones.
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The diagram below illustrates how two _______-acting elements are positioned near the gene that they regulate.

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DNA methylation patterns in parental cells are established and maintained in progeny cells by which of the following mechanisms?
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Suppose a mutation renders a cell incapable of producing functional P-TEFb. What effect would the mutation have on this cell?
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The lac operator consists of approximately 20 base pairs of DNA located
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What is the role of the transcription factor c-Myc in human embryonic stem cells?
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How can epigenetic changes explain why identical twins develop different physical characteristics later in life?
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Which characteristic of chromatin would you expect to see increase when incubated with histone acetyltransferase enzymes?
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Some bacterial promoter regions are regulated by _______ that stimulate RNA polymerase binding and by _______ that block RNA polymerase binding.
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If you had genomic DNA and a purified transcription factor, how might you use that to determine the DNA sequence to which the transcription factor binds?
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The nucleus of a mature mouse skin cell is transplanted into an enucleated mouse embryo. The embryo develops into a blastocyst but then stalls at this stage. How can epigenetics explain this?
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A student made the following table to summarize what he had learned about bacterial transcriptional control mechanisms. A fellow classmate pointed out that the table is not accurate. Which statement describes the problem? Type of regulatory protein Operon transcriptional response to wild- type regulatory protein Operon transcriptional response to mutated regulatory protein (rendered nonfunctional) Positive control Activator On Off Negative control Repressor Off Off
(Multiple Choice)
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P-TEFb contains a _______ that phosphorylates NELF, DSIF, and serine 2 in the C-terminal domain of RNA polymerase, all of which lead to re-activation of RNA polymerase and transcriptional elongation.
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Eukaryotic gene repressor proteins are thought to act by binding to
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