Exam 19: Diseases of the Hematological System

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Case Study
 BD is a 15 yo female who is seen by her physician for her yearly check up. The physician determines that BD has microcytic anemia. Her diet recall is as follows:
 B- bagel with cream cheese  D- 1 cup of pasta
 6 oz milk  ½ cup tomato sauce
 L- turkey sandwich on whole-wheat bread  2 pieces garlic bread
 lettuce  8 oz iced tea
 mayonnaise  S- apple
 potato chips  
 8 oz iced tea  
-What substance in this food inhibits iron absorption?

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Correct Answer:
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C

Which of the following groups are at the least risk of developing iron-deficiency anemia?

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B

As the RBC die, the iron is recycled and stored in the liver as:

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Correct Answer:
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B

A serious complication of BMT that occurs in 30-50% of patients is:

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Which of the following foods is highest in bioavailable Fe?

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In Fe-deficiency anemia, it would be common to find an increased level of which of the following laboratory values?

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Which of the following statements is not true?

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The mechanism by which anemia frequently occurs in those patients with alcoholic liver disease is best described as:

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If folate is administered orally to a patient who presents with anemia that is actually a B12-deficient anemia, the result is which of the following?

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Which of the following is a good source of vitamin B12?

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PS is an 87 yo M admitted to the hospital for failure to thrive.While hospitalized, a physician has determined that PS also has megaloblastic anemia. -Given PS's history, what is a likely cause of the megaloblastic anemia?

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Which of the following is a potential concern for the MD prescribing folate in this case?

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Immature erythrocytes are called:

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Case Study
 BD is a 15 yo female who is seen by her physician for her yearly check up. The physician determines that BD has microcytic anemia. Her diet recall is as follows:
 B- bagel with cream cheese  D- 1 cup of pasta
 6 oz milk  ½ cup tomato sauce
 L- turkey sandwich on whole-wheat bread  2 pieces garlic bread
 lettuce  8 oz iced tea
 mayonnaise  S- apple
 potato chips  
 8 oz iced tea  
-The registered dietitian recommends iron supplements for BD She should also educate BD on _____, given it is a common complaint when using iron supplements

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What is the etiology of pernicious anemia?

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Matching
hemophilia
an anemia brought on by the rapid, premature destruction of red blood cells in circulation, which may be precipitated by vitamin E deficiency
porphyria
an antigen-induced hemolytic anemia of the newborn or premature infant, as a result of incompatibility of maternal Rh factors with the neonate
thalassemia
atrophy of the lining of the stomach
Correct Answer:
Verified
Premises:
Responses:
hemophilia
an anemia brought on by the rapid, premature destruction of red blood cells in circulation, which may be precipitated by vitamin E deficiency
porphyria
an antigen-induced hemolytic anemia of the newborn or premature infant, as a result of incompatibility of maternal Rh factors with the neonate
thalassemia
atrophy of the lining of the stomach
erythroblastosis fetalis
a symptom that is often a result of the decrement in blood constituents
hemoglobinuria
a cluster of blood-related disorders characterized by abnormal porphyrin synthesis or metabolism
hypochromic
an autoimmune, chronic inflammatory disease that affects the connective tissue
aplastic anemia
iron overload
microcytic
a hereditary disease of genetically altered red blood cells that have a sickled shape, carry abnormally formed hemoglobin, and have abnormal transport capabilities for oxygen
SLE
refers to an immature, large red blood cell that is oval in shape and abnormal
megaloblastic
a group of related blood disorders involving abnormal globin subunits in the hemoglobin molecule
pica
a reduction in the numbers of all the blood elements
macrocytic
scar tissue formation with calcification or hardening of the connective tissue used in repair of tissue damage
pancytopenia
refers to abnormally large cell size
pernicious anemia
excess free hemoglobin build-up in circulation
cicatrix
the anemia associated with B12 deficiency
hemoglobinemia
a form of anemia characterized by the appearance of immature ferritin-containing blast marrow cells in circulation
kernicterus
an inherited disorder of blood clotting, with pronounced bleeding upon tissue injury
hemochromatosis
long-term hyperplasia of hematological tissues, with concomitant overproduction of abnormal cells, growth factors, chemokines, cytokines, and hormones involved in hematopoiesis
sickle cell anemia
refers to abnormally small cell size
atrophic gastritis
excessive free hemoglobin spillage into the urine
anemia
eating of abnormal items, or non-nutritive substances
chronic myeloproliferative disease
abnormally pale in color upon visual inspection under a microscope
hemolytic anemia
infiltration of excessive amounts of bilirubin into the neurons of the spinal cord and brain
sideroblastic anemia
idiopathic anemia from abnormal, deficient, or absent red cell production due to bone marrow disorders
(Matching)
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Deficiencies of protein, vitamin C, or iron or impaired heme synthesis generally would result in which type of anemia?

(Multiple Choice)
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Which of the following is a good source of folate?

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Which of the following accurately describes the effect on iron absorption?

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Case Study
 BD is a 15 yo female who is seen by her physician for her yearly check up. The physician determines that BD has microcytic anemia. Her diet recall is as follows:
 B- bagel with cream cheese  D- 1 cup of pasta
 6 oz milk  ½ cup tomato sauce
 L- turkey sandwich on whole-wheat bread  2 pieces garlic bread
 lettuce  8 oz iced tea
 mayonnaise  S- apple
 potato chips  
 8 oz iced tea  
-Aside from the above, which of the following could be ruled out as a potential cause of BD's anemia?

(Multiple Choice)
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