Exam 19: Amines

Devise an efficient method for preparing 4-bromobenzonitrile from benzene.

The final product is a derivative of Amonafide, a drug used to treat breast cancer (J. Med. Chem. 2007, 4122). Complete each step of the synthesis by filling in the necessary reagents.

When a 1° amine reacts with an alkyl sulfonyl chloride, the major organic product is ________.

Devise an efficient method for preparing ethylisopropylamine from ethylamine.

Devise an efficient method for preparing 1-pentanamine from 1-chloropentane.

Provide the major organic product of the following reaction.

Provide the structure of the major organic product in the reaction below.

Provide the structure of the major organic product in the reaction below.

When CH₃CH₂CHO reacts with PhNHNH₂ under conditions of acid catalysis, the major organic product is ________.

Which of the following chloropyridines readily undergo nucleophilic substitution upon treatment with NaCN?

Provide the structure of the major organic product in the reaction below.

Complete the short synthesis below by providing the necessary reagents.

Provide the major organic product of the following reaction.

What common names for 1,4-butanediamine and 1,5-pentanediamine are derived from their characteristic pungent odors?

Name the compound shown below.

A three-carbon, nitrogen-containing compound exhibits 3 ¹³C NMR peaks (d 11.2, 27.3, and 44.9). Which of the following compounds best matches this spectral data?

Sec-Butylamine is the common name of what compound?

Which of the following amines is most soluble in water?

Provide the structure of the major organic product in the reaction below.

Provide the name of the compound shown below.