Exam 20: Carboxylic Acids

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Propose a reasonable synthetic route to prepare butanal from butanoic acid.

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Which of the following is the strongest acid?

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2-Phenylethanol yields what acid upon treatment with hot chromic acid or permanganate?

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Provide the major organic product of the reaction shown below. Provide the major organic product of the reaction shown below.

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Provide the major organic product of the reaction shown below. Provide the major organic product of the reaction shown below.

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Which of the following reagents can be used to convert a carboxylic acid directly into its corresponding acid chloride derivative?

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Which of the following compounds is the strongest acid?

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The methyl ester of a carboxylic acid can be synthesized directly using ________.

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Lithium aluminum hydride reduces carboxylic acids to primary alcohols via what intermediate?

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Provide the structure of 3,3-dimethylheptanoic acid.

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Which of the following must be converted into a carboxylic acid through nitrile hydrolysis rather than through a Grignard synthesis with Mg/ether followed with dry CO2 and work-up with H3O+? Which of the following must be converted into a carboxylic acid through nitrile hydrolysis rather than through a Grignard synthesis with Mg/ether followed with dry CO<sub>2</sub> and work-up with H<sub>3</sub>O<sup>+</sup>?

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The combination of a carbonyl group and a hydroxyl group on the same carbon atom is called a ________ group.

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How does the O-H stretch in the IR spectrum of a carboxylic acid differ from the O-H stretch of an alcohol?

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Provide the major organic product of the reaction shown below. Provide the major organic product of the reaction shown below.

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Which of the following would be the preferred reagents used in the following synthesis? Which of the following would be the preferred reagents used in the following synthesis?

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Provide the structure of zinc undecanoate, a major component in several athlete's foot medications.

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What is the common name for the following compound? What is the common name for the following compound?

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Provide the major organic product of the reaction shown below. Provide the major organic product of the reaction shown below.

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Provide the major organic product of the following reaction. Provide the major organic product of the following reaction.

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Provide a detailed, stepwise mechanism for the methylation of a carboxylic acid with diazomethane.

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