Question 1

If a new drug is developed that is a potent CB1 antagonist, one would expect this drug to

Accepted Answer

A)  produce a "high" similar to that of marijuana. 
B)  repair memory in elderly dementia patients. 
C)  impair the reinforcing actions of drugs such as nicotine, cocaine and alcohol. 
D)  suppress D2 receptors. 
E)  produce conditioned aversion for the areas in which the drug is experienced. 
A)  produce a "high" similar to that of marijuana. 
B)  repair memory in elderly dementia patients. 
C)  impair the reinforcing actions of drugs such as nicotine, cocaine and alcohol. 
D)  suppress D2 receptors. 
E)  produce conditioned aversion for the areas in which the drug is experienced.

Question 2

Early changes in the brain during exposure to addictive drugs involves the insertion of ________ receptors into neuron membranes located within the ________.

Accepted Answer

A)  GABA; hippocampus 
B)  D2; nucleus accumbens 
C)  AMPA; VTA 
D)  glycine; VTA 
E)  AMPA; amygdala 
A)  GABA; hippocampus 
B)  D2; nucleus accumbens 
C)  AMPA; VTA 
D)  glycine; VTA 
E)  AMPA; amygdala

Question 3

Administration of haloperidol to a person before he or she consumed alcohol would be expected to

Accepted Answer

A)  decrease his or her alcohol consumption. 
B)  increase his or her alcohol consumption. 
C)  reduce the sedating effect of alcohol. 
D)  increase the reinforcing effect of alcohol. 
E)  intensify the magnitude of their hangover the following day. 
A)  decrease his or her alcohol consumption. 
B)  increase his or her alcohol consumption. 
C)  reduce the sedating effect of alcohol. 
D)  increase the reinforcing effect of alcohol. 
E)  intensify the magnitude of their hangover the following day.

Question 4

________________ cause a release of dopamine by running dopamine transporters in reverse.

Accepted Answer

The answer of ________________ cause a release of dopamine by...

Question 5

Activation of neurons within the ________ appears to play a key role in the early reinforcing actions of drugs.

Accepted Answer

A)  thalamus 
B)  nucleus accumbens 
C)  amygdala 
D)  dorsal striatum 
E)  hippocampus 
A)  thalamus 
B)  nucleus accumbens 
C)  amygdala 
D)  dorsal striatum 
E)  hippocampus

Question 6

The harmful effects of alcohol on learning and memory may reflect

Accepted Answer

A)  the release of GABA within the cerebellum. 
B)  damage to cholinergic cells in the hippocampus. 
C)  interference with NMDA receptors and long-term potentiation. 
D)  an upregulation of GABA transmission in brain. 
E)  loss of glial cells in layers 4-6 of the cortex. 
A)  the release of GABA within the cerebellum. 
B)  damage to cholinergic cells in the hippocampus. 
C)  interference with NMDA receptors and long-term potentiation. 
D)  an upregulation of GABA transmission in brain. 
E)  loss of glial cells in layers 4-6 of the cortex.

Question 7

Opiate receptors in the periaqueductal gray matter (PAG) are responsible for the ________ caused by opiate drugs.

Accepted Answer

The answer of Opiate receptors in the periaqueductal gray matter...

Question 8

Which of the following factors is a predictor of your risk for hospitalization for schizophrenia?

Accepted Answer

A)  your religious preference 
B)  smoking more than 10 cigarettes per day 
C)  whether you had served in the military 
D)  consuming at least 10 diet drinks per day 
E)  having a friend who developed schizophrenia 
A)  your religious preference 
B)  smoking more than 10 cigarettes per day 
C)  whether you had served in the military 
D)  consuming at least 10 diet drinks per day 
E)  having a friend who developed schizophrenia

Question 9

Which of the following illustrates the concept of punishment?

Accepted Answer

A)  A man ingests an aspirin to rid himself of a strong headache. 
B)  A hungry rat presses a lever to obtain a food pellet. 
C)  A rat presses a lever that results in delivery of a shock through the floor of the chamber. 
D)  A woman injects heroin into her veins to obtain a "rush." 
E)  A child is given a cookie after screaming at the dinner table. 
A)  A man ingests an aspirin to rid himself of a strong headache. 
B)  A hungry rat presses a lever to obtain a food pellet. 
C)  A rat presses a lever that results in delivery of a shock through the floor of the chamber. 
D)  A woman injects heroin into her veins to obtain a "rush." 
E)  A child is given a cookie after screaming at the dinner table.

Question 10

You would expect that an injection of an opiate drug into the ________ would activate dopamine neurons in the nucleus accumbens.

Accepted Answer

A)  ventral tegmental area 
B)  medial septal region 
C)  periaqueductal gray matter 
D)  preoptic area 
E)  cingulate cortex 
A)  ventral tegmental area 
B)  medial septal region 
C)  periaqueductal gray matter 
D)  preoptic area 
E)  cingulate cortex

Question 11

Rats that self-injected ________ were more likely to die from an overdose than rats that self-injected ________.

Accepted Answer

The answer of Rats that self-injected ________ were more likely...

Question 12

Cocaine and amphetamine both increase dopamine action. Cocaine specifically _______________ and amphetamine __________________.

Accepted Answer

A)  blocks the dopamine transporter; stimulates the autoreceptor 
B)  stimulates the release of dopamine; stimulates the autoreceptor 
C)  blocks the dopamine transporter; stimulates the release of dopamine 
D)  stimulates the release of dopamine; blocks the dopamine transporter 
E)  stimulates the autoreceptor; blocks the dopamine transporter 
A)  blocks the dopamine transporter; stimulates the autoreceptor 
B)  stimulates the release of dopamine; stimulates the autoreceptor 
C)  blocks the dopamine transporter; stimulates the release of dopamine 
D)  stimulates the release of dopamine; blocks the dopamine transporter 
E)  stimulates the autoreceptor; blocks the dopamine transporter

Question 13

The ________ plays a key role in producing opiate withdrawal symptoms.

Accepted Answer

The answer of The ________ plays a key role in...

Question 14

The common aspect of all natural reinforcers relates to

Accepted Answer

A)  the release of dopamine within the nucleus accumbens. 
B)  the release of norepinephrine within the locus coeruleus. 
C)  the release of dopamine within the lateral hypothalamus. 
D)  inactivation of the frontal cortex. 
E)  activation of the medulla. 
A)  the release of dopamine within the nucleus accumbens. 
B)  the release of norepinephrine within the locus coeruleus. 
C)  the release of dopamine within the lateral hypothalamus. 
D)  inactivation of the frontal cortex. 
E)  activation of the medulla.

Question 15

Explain how drugs of abuse may act via the same substrate engaged by natural rewards.

Accepted Answer

The mesolimbic dopamine system terminate

Question 16

The common aspect of all natural reinforcers relates to the release of ________ within the nucleus accumbens.

Accepted Answer

The answer of The common aspect of all natural reinforcers...

Question 17

The release of endogenous cannabinoids facilitates the activity of CA1 pyramidal cells and ____________ long-term potentiation, which ___________________.

Accepted Answer

A)  facilitates; enhances memory 
B)  facilitates; produces memory deficits 
C)  inhibits; enhances memory 
D)  inhibits; produces memory deficits 
E)  reduces; enhances memory 
A)  facilitates; enhances memory 
B)  facilitates; produces memory deficits 
C)  inhibits; enhances memory 
D)  inhibits; produces memory deficits 
E)  reduces; enhances memory

Question 18

During abstinence, the activity of the ___________ prefrontal cortex of people who abused cocaine was lower than that of non-cocaine-using participants.

Accepted Answer

A)  dorsal 
B)  ventromedial 
C)  dorsolateral 
D)  medial 
E)  rostral 
A)  dorsal 
B)  ventromedial 
C)  dorsolateral 
D)  medial 
E)  rostral

Question 19

Explain how the "reinstatement" procedure is used to model drug craving.

Accepted Answer

Extended experience with a drug results

Question 20

Summarize the association between schizophrenia and drug abuse.

Accepted Answer

There is a comorbidity between schizophr

If a new drug is developed that is a potent CB1 antagonist, one would expect this drug to

Early changes in the brain during exposure to addictive drugs involves the insertion of receptors into neuron membranes located within the .

Administration of haloperidol to a person before he or she consumed alcohol would be expected to

________________ cause a release of dopamine by running dopamine transporters in reverse.

Activation of neurons within the ________ appears to play a key role in the early reinforcing actions of drugs.

The harmful effects of alcohol on learning and memory may reflect

Opiate receptors in the periaqueductal gray matter (PAG) are responsible for the ________ caused by opiate drugs.

Which of the following factors is a predictor of your risk for hospitalization for schizophrenia?

Which of the following illustrates the concept of punishment?

You would expect that an injection of an opiate drug into the ________ would activate dopamine neurons in the nucleus accumbens.

Rats that self-injected were more likely to die from an overdose than rats that self-injected .

Cocaine and amphetamine both increase dopamine action. Cocaine specifically _ and amphetamine ____.

The ________ plays a key role in producing opiate withdrawal symptoms.

The common aspect of all natural reinforcers relates to

Explain how drugs of abuse may act via the same substrate engaged by natural rewards.

The common aspect of all natural reinforcers relates to the release of ________ within the nucleus accumbens.

The release of endogenous cannabinoids facilitates the activity of CA1 pyramidal cells and long-term potentiation, which _______.

During abstinence, the activity of the ___________ prefrontal cortex of people who abused cocaine was lower than that of non-cocaine-using participants.

Explain how the "reinstatement" procedure is used to model drug craving.

Summarize the association between schizophrenia and drug abuse.

Introduction

Structure and Function of Cells of the Nervous System

Structure of the Nervous System

Psychopharmacology

Methods and Strategies of Research

Vision

Audition, the Body Senses, and the Chemical Senses

Control of Movement

Sleep and Biological Rhythms

Reproductive Behavior

Emotion

Ingestive Behavior

Learning and Memory

Human Communication

Neurological Disorders

Schizophrenia and the Affective Disorders

Anxiety Disorders, Autistic Disorder, attention-Deficithyperactivity Disorder, and Stress Disorders

Filters

Exam 18: Substance Abuse

If a new drug is developed that is a potent CB1 antagonist, one would expect this drug to

Early changes in the brain during exposure to addictive drugs involves the insertion of ________ receptors into neuron membranes located within the ________.

Administration of haloperidol to a person before he or she consumed alcohol would be expected to

________________ cause a release of dopamine by running dopamine transporters in reverse.

Activation of neurons within the ________ appears to play a key role in the early reinforcing actions of drugs.

The harmful effects of alcohol on learning and memory may reflect

Opiate receptors in the periaqueductal gray matter (PAG) are responsible for the ________ caused by opiate drugs.

Which of the following factors is a predictor of your risk for hospitalization for schizophrenia?

Which of the following illustrates the concept of punishment?

You would expect that an injection of an opiate drug into the ________ would activate dopamine neurons in the nucleus accumbens.

Rats that self-injected ________ were more likely to die from an overdose than rats that self-injected ________.

Cocaine and amphetamine both increase dopamine action. Cocaine specifically _______________ and amphetamine __________________.

The ________ plays a key role in producing opiate withdrawal symptoms.

The common aspect of all natural reinforcers relates to

Explain how drugs of abuse may act via the same substrate engaged by natural rewards.

The common aspect of all natural reinforcers relates to the release of ________ within the nucleus accumbens.

The release of endogenous cannabinoids facilitates the activity of CA1 pyramidal cells and ____________ long-term potentiation, which ___________________.

During abstinence, the activity of the ___________ prefrontal cortex of people who abused cocaine was lower than that of non-cocaine-using participants.

Explain how the "reinstatement" procedure is used to model drug craving.

Summarize the association between schizophrenia and drug abuse.

Introduction

Structure and Function of Cells of the Nervous System

Structure of the Nervous System

Psychopharmacology

Methods and Strategies of Research

Vision

Audition, the Body Senses, and the Chemical Senses

Control of Movement

Sleep and Biological Rhythms

Reproductive Behavior

Emotion

Ingestive Behavior

Learning and Memory

Human Communication

Neurological Disorders

Schizophrenia and the Affective Disorders

Anxiety Disorders, Autistic Disorder, attention-Deficithyperactivity Disorder, and Stress Disorders

Filters

Early changes in the brain during exposure to addictive drugs involves the insertion of receptors into neuron membranes located within the .

Rats that self-injected were more likely to die from an overdose than rats that self-injected .

Cocaine and amphetamine both increase dopamine action. Cocaine specifically _ and amphetamine ____.

The release of endogenous cannabinoids facilitates the activity of CA1 pyramidal cells and long-term potentiation, which _______.