Question 1

Which of the following is NOT a stop codon?

Accepted Answer

A)  UGA 
B)  UUA 
C)  UAG 
D)  UAA 
A)  UGA 
B)  UUA 
C)  UAG 
D)  UAA

Question 2

Which two things act together to terminate translation? (Choose two.)

Accepted Answer

A)  Rho factor 
B)  release factor 
C)  stop codon 
D)  Met codon 
E)  filled P site 
A)  Rho factor 
B)  release factor 
C)  stop codon 
D)  Met codon 
E)  filled P site

Question 3

What is the least number of tRNAs needed to carry isoleucine,and what is/are the anticodon(s)?

Accepted Answer

A)  one-5′IAU3′ 
B)  one-5′UAU3′ 
C)  two-5′GAU3′ and 5′UAU3′ 
D)  two-5′AUA3′ and 5′UAI3′ 
A)  one-5′IAU3′ 
B)  one-5′UAU3′ 
C)  two-5′GAU3′ and 5′UAU3′ 
D)  two-5′AUA3′ and 5′UAI3′

Question 4

A polyribosome can be found in which of the following types of cells?

Accepted Answer

A)  prokaryotic 
B)  eukaryotic 
C)  both 
A)  prokaryotic 
B)  eukaryotic 
C)  both

Question 5

The peptidyltransferase complex is a component of which of the following?

Accepted Answer

A)  DNA 
B)  tRNA 
C)  The ribosome 
D)  The growing polypeptide 
E)  mRNA 
A)  DNA 
B)  tRNA 
C)  The ribosome 
D)  The growing polypeptide 
E)  mRNA

Question 6

Transcription and translation may occur simultaneously in prokaryotic cells.

Accepted Answer

A) True 
 B)False

Question 7

Kozak's rules for translation are similar to those for transcription in prokaryotes in that they both contain consensus sequences.In prokaryotes,the promoter consensus sequences are at −35 and −10.Where is the consensus sequence for translational initiation according to Kozak's rules?

Accepted Answer

A)  −6 to +4 
B)  −12 to −2 
C)  +1 to +10 
D)  −35 to −10 
A)  −6 to +4 
B)  −12 to −2 
C)  +1 to +10 
D)  −35 to −10

Question 8

The anticodon on the mRNA recognizes the codon on the tRNA.

Accepted Answer

A) True 
 B)False

Question 9

You perform a cell free translation experiment like Nirenberg and Matthaei.You start with 60% C and 40% A.What relative amount of radiolabeled proline do you expect in the translated polypeptides?

Accepted Answer

A)  36% 
B)  22% 
C)  14% 
D)  28% 
A)  36% 
B)  22% 
C)  14% 
D)  28%

Question 10

A tRNA that has an amino acid attached is called ________.

Accepted Answer

A)  rRNA 
B)  degenerate tRNA 
C)  coding tRNA 
D)  charged tRNA 
E)  None of the answers are correct. 
A)  rRNA 
B)  degenerate tRNA 
C)  coding tRNA 
D)  charged tRNA 
E)  None of the answers are correct.

Question 11

Mitochondria import their ribosomes from the pool of ribosomes in the cytoplasm.

Accepted Answer

A) True 
 B)False

Question 12

A tRNA's anticodon is 5′GGC3′.What amino acid is attached to it?

Accepted Answer

A)  Glycine 
B)  Proline 
C)  Alanine 
D)  Arginine 
A)  Glycine 
B)  Proline 
C)  Alanine 
D)  Arginine

Question 13

A tRNA's anticodon is 5′GGC3′.What amino acid is attached to it?

Accepted Answer

A)  glycine 
B)  proline 
C)  alanine 
D)  arginine 
A)  glycine 
B)  proline 
C)  alanine 
D)  arginine

Question 14

Which of the following are true regarding the experiments of Beadle and Tatum?

Accepted Answer

A)  They were able to create loss-of-function mutations in any enzyme they chose. 
B)  They used the mold Neurospora as a model organism. 
C)  They isolated strains that could not grow on minimal media. 
D)  They established the link between a gene and an enzyme or protein. 
A)  They were able to create loss-of-function mutations in any enzyme they chose. 
B)  They used the mold Neurospora as a model organism. 
C)  They isolated strains that could not grow on minimal media. 
D)  They established the link between a gene and an enzyme or protein.

Question 15

What site does the initiator tRNA bind to on the ribosome?

Accepted Answer

A)  A 
B)  E 
C)  P 
A)  A 
B)  E 
C)  P

Question 16

The scientist(s)________ studied Neurospora mutants that were altered in their nutritional requirements and hypothesized that one gene encodes one enzyme.

Accepted Answer

A)  Garrod 
B)  Nirenberg and Matthaei 
C)  Khorana and colleagues 
D)  Nirenberg and Leder 
E)  Beadle and Tatum 
A)  Garrod 
B)  Nirenberg and Matthaei 
C)  Khorana and colleagues 
D)  Nirenberg and Leder 
E)  Beadle and Tatum

Question 17

RF1 and RF2 are active during ________.

Accepted Answer

A)  initiation 
B)  elongation 
C)  termination 
D)  cotranslational import 
A)  initiation 
B)  elongation 
C)  termination 
D)  cotranslational import

Question 18

A protein called actin consists of 376 amino acids. The mRNA for actin must be longer than

Accepted Answer

A)  125 nucleotides. 
B)  376 nucleotides. 
C)  1128 nucleotides. 
D)  3384 nucleotides. 
A)  125 nucleotides. 
B)  376 nucleotides. 
C)  1128 nucleotides. 
D)  3384 nucleotides.

Question 19

What does eIF5 act to recruit during the initiation stage?

Accepted Answer

A)  the mRNA 
B)  the polypeptide 
C)  the large ribosomal subunit 
D)  termination GTPases 
E)  the 7-methylguanosine cap 
A)  the mRNA 
B)  the polypeptide 
C)  the large ribosomal subunit 
D)  termination GTPases 
E)  the 7-methylguanosine cap

Question 20

The C-terminus of a polypeptide always contains

Accepted Answer

A)  a stop codon. 
B)  a carboxyl group. 
C)  an amino group. 
D)  carbon dioxide. 
E)  a stop amino acid. 
A)  a stop codon. 
B)  a carboxyl group. 
C)  an amino group. 
D)  carbon dioxide. 
E)  a stop amino acid.

Exam 15: Translation of MRNA

Which of the following is NOT a stop codon?

Which two things act together to terminate translation? (Choose two.)

What is the least number of tRNAs needed to carry isoleucine,and what is/are the anticodon(s)?

A polyribosome can be found in which of the following types of cells?

The peptidyltransferase complex is a component of which of the following?

Transcription and translation may occur simultaneously in prokaryotic cells.

Kozak's rules for translation are similar to those for transcription in prokaryotes in that they both contain consensus sequences.In prokaryotes,the promoter consensus sequences are at −35 and −10.Where is the consensus sequence for translational initiation according to Kozak's rules?

The anticodon on the mRNA recognizes the codon on the tRNA.

You perform a cell free translation experiment like Nirenberg and Matthaei.You start with 60% C and 40% A.What relative amount of radiolabeled proline do you expect in the translated polypeptides?

A tRNA that has an amino acid attached is called ________.

Mitochondria import their ribosomes from the pool of ribosomes in the cytoplasm.

A tRNA's anticodon is 5′GGC3′.What amino acid is attached to it?

A tRNA's anticodon is 5′GGC3′.What amino acid is attached to it?

Which of the following are true regarding the experiments of Beadle and Tatum?

What site does the initiator tRNA bind to on the ribosome?

The scientist(s)________ studied Neurospora mutants that were altered in their nutritional requirements and hypothesized that one gene encodes one enzyme.

RF1 and RF2 are active during ________.

A protein called actin consists of 376 amino acids. The mRNA for actin must be longer than

What does eIF5 act to recruit during the initiation stage?

The C-terminus of a polypeptide always contains

Overview of Genetics

Reproduction and Chromosome Transmission

Mendelian Inheritance

Sex Determination and Sex Chromosomes

Extensions of Mendelian Inheritance

Extranuclear Inheritance, Imprinting, and Maternal Effect

Genetic Linkage and Mapping in Eukaryotes

Variation in Chromosome Structure and Number

Genetics in Bacteria

Genetics of Viruses

Molecular Structure of DNA and RNA

Molecular Structure of Chromosomes and Transposition

Dna Replication and Recombination

Gene Transcription and RNA Modification

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes

Non-Coding Rnas

Gene Mutation and DNA Repair

Molecular Technologies

Genomics

Medical Genetics and Cancer

Population Genetics

Quantitative Genetics

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