Question 1

Inversions are contained within what percent of the human population?

Accepted Answer

A)  less than 1% 
B)  approximately 2% 
C)  approximately 5% 
D)  greater than 10% 
A)  less than 1% 
B)  approximately 2% 
C)  approximately 5% 
D)  greater than 10% B

Question 2

Select the pairs that correctly match an aneuploid condition to its genotype.

Accepted Answer

A)  Edward syndrome - trisomy 18 
B)  Down syndrome - trisomy 21 
C)  Jacobs syndrome - XYY 
D)  Turner syndrome - XXY 
E)  Klinefelter - XO 
A)  Edward syndrome - trisomy 18 
B)  Down syndrome - trisomy 21 
C)  Jacobs syndrome - XYY 
D)  Turner syndrome - XXY 
E)  Klinefelter - XO A,B,C

Question 3

Inversion loops can occur in which of the following?

Accepted Answer

A)  paracentric inversions 
B)  pericentric inversions 
C)  gene duplications 
D)  reciprocal translocations 
E)  both paracentric inversions and pericentric inversions 
A)  paracentric inversions 
B)  pericentric inversions 
C)  gene duplications 
D)  reciprocal translocations 
E)  both paracentric inversions and pericentric inversions E

Question 4

Due to the formation of an inversion loop,sections of DNA may either be duplicated or deleted.

Accepted Answer

A) True 
 B)False

Question 5

A loss of an internal portion of a chromosome is called a(n)________.

Accepted Answer

A)  reciprocal translocation 
B)  terminal deficiency 
C)  interstitial deletion 
D)  gene duplication 
A)  reciprocal translocation 
B)  terminal deficiency 
C)  interstitial deletion 
D)  gene duplication

Question 6

Which of following expressions denotes a trisomic organism?

Accepted Answer

A)  3n 
B)  2n-1 
C)  2n+1 
D)  2n+2 
A)  3n 
B)  2n-1 
C)  2n+1 
D)  2n+2

Question 7

Given the following sequence of genes on a chromosome,determine what change in chromosome structure occurred.The asterisk (*)indicates the centromere.
Before:A B C D * E F G H
After:A B C D * E F E F G H

Accepted Answer

A)  terminal deficiency 
B)  interstitial deficiency 
C)  inversion 
D)  gene duplication 
A)  terminal deficiency 
B)  interstitial deficiency 
C)  inversion 
D)  gene duplication

Question 8

Which human cells exhibit endopolyploidy?

Accepted Answer

A)  sex cells 
B)  nerve cells 
C)  all somatic cells 
D)  liver cells 
E)  red blood cells 
A)  sex cells 
B)  nerve cells 
C)  all somatic cells 
D)  liver cells 
E)  red blood cells

Question 9

Describe endopolyploidy,and how it might benefit an organism.

Accepted Answer

A)  Portions of the organism have extra copies of all chromosomes, for producing additional gene products. 
B)  The entire organism has extra copies of certain chromosomes, for producing additional gene products. 
C)  The entire organism has extra copies of all chromosomes, to act as backup in case of DNA damage. 
D)  Portions of the organism have extra copies of certain genes, for the functions of specialized cell types. 
A)  Portions of the organism have extra copies of all chromosomes, for producing additional gene products. 
B)  The entire organism has extra copies of certain chromosomes, for producing additional gene products. 
C)  The entire organism has extra copies of all chromosomes, to act as backup in case of DNA damage. 
D)  Portions of the organism have extra copies of certain genes, for the functions of specialized cell types.

Question 10

Examples of euploidy include

Accepted Answer

A)  diploidy. 
B)  triploidy. 
C)  tetraploidy. 
D)  polyploidy. 
E)  aneuploidy. 
A)  diploidy. 
B)  triploidy. 
C)  tetraploidy. 
D)  polyploidy. 
E)  aneuploidy.

Question 11

The ends of chromosomes have areas of repeated DNA called centromeres.

Accepted Answer

A) True 
 B)False

Question 12

Homologous genes within a species are called paralogs.

Accepted Answer

A) True 
 B)False

Question 13

Edward and Patau syndromes are examples of ________.

Accepted Answer

A)  aneuploidy 
B)  allopolyploidy 
C)  autopolyploidy 
D)  translocations 
A)  aneuploidy 
B)  allopolyploidy 
C)  autopolyploidy 
D)  translocations

Question 14

The short arm of a chromosome is denoted by the letter ________ and the long arm by the letter ________.

Accepted Answer

A)  p; q 
B)  s; l 
C)  q; p 
D)  c; d 
A)  p; q 
B)  s; l 
C)  q; p 
D)  c; d

Question 15

If a disease is associated with copy number variation,that suggests that it is caused by the presence of

Accepted Answer

A)  mRNA transcripts missing the translation STOP sequence. 
B)  a much longer version of a gene. 
C)  a duplicated or deleted copy of a gene. 
D)  extra telomeres. 
A)  mRNA transcripts missing the translation STOP sequence. 
B)  a much longer version of a gene. 
C)  a duplicated or deleted copy of a gene. 
D)  extra telomeres.

Question 16

Which of the following describes an organism with two complete sets of chromosomes from two different species?

Accepted Answer

A)  tetraploid 
B)  aneuploid 
C)  allodiploid 
D)  allotetraploid 
A)  tetraploid 
B)  aneuploid 
C)  allodiploid 
D)  allotetraploid

Question 17

Inversions represent a change in the total genetic material of a chromosome.

Accepted Answer

A) True 
 B)False

Question 18

What process is the cause of human genetic diseases such a cri-du-chat (or Lejeune)syndrome?

Accepted Answer

A)  translocation 
B)  duplication 
C)  deletion 
D)  inversion 
A)  translocation 
B)  duplication 
C)  deletion 
D)  inversion

Question 19

Genetic abnormalities that occur after fertilization may result in some tissues of the body differing in their genetic composition.This is called ________.

Accepted Answer

A)  mosaicism 
B)  polyploidy 
C)  polypheny 
D)  genetic variation 
A)  mosaicism 
B)  polyploidy 
C)  polypheny 
D)  genetic variation

Question 20

What causes gene duplications?

Accepted Answer

A)  the crossing over of misaligned chromosomes 
B)  deletion of important genetic information 
C)  reciprocal translocations 
D)  position effect 
E)  None of these choices are correct. 
A)  the crossing over of misaligned chromosomes 
B)  deletion of important genetic information 
C)  reciprocal translocations 
D)  position effect 
E)  None of these choices are correct.

Exam 8: Variation in Chromosome Structure and Number

Inversions are contained within what percent of the human population?

Select the pairs that correctly match an aneuploid condition to its genotype.

Inversion loops can occur in which of the following?

Due to the formation of an inversion loop,sections of DNA may either be duplicated or deleted.

A loss of an internal portion of a chromosome is called a(n)________.

Which of following expressions denotes a trisomic organism?

Given the following sequence of genes on a chromosome,determine what change in chromosome structure occurred.The asterisk (*)indicates the centromere. Before:A B C D * E F G H After:A B C D * E F E F G H

Which human cells exhibit endopolyploidy?

Describe endopolyploidy,and how it might benefit an organism.

Examples of euploidy include

The ends of chromosomes have areas of repeated DNA called centromeres.

Homologous genes within a species are called paralogs.

Edward and Patau syndromes are examples of ________.

The short arm of a chromosome is denoted by the letter ________ and the long arm by the letter ________.

If a disease is associated with copy number variation,that suggests that it is caused by the presence of

Which of the following describes an organism with two complete sets of chromosomes from two different species?

Inversions represent a change in the total genetic material of a chromosome.

What process is the cause of human genetic diseases such a cri-du-chat (or Lejeune)syndrome?

Genetic abnormalities that occur after fertilization may result in some tissues of the body differing in their genetic composition.This is called ________.

What causes gene duplications?

Overview of Genetics

Reproduction and Chromosome Transmission

Mendelian Inheritance

Sex Determination and Sex Chromosomes

Extensions of Mendelian Inheritance

Extranuclear Inheritance, Imprinting, and Maternal Effect

Genetic Linkage and Mapping in Eukaryotes

Genetics in Bacteria

Genetics of Viruses

Molecular Structure of DNA and RNA

Molecular Structure of Chromosomes and Transposition

Dna Replication and Recombination

Gene Transcription and RNA Modification

Translation of MRNA

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes

Non-Coding Rnas

Gene Mutation and DNA Repair

Molecular Technologies

Genomics

Medical Genetics and Cancer

Population Genetics

Quantitative Genetics

Filters

Given the following sequence of genes on a chromosome,determine what change in chromosome structure occurred.The asterisk ()indicates the centromere. Before:A B C D E F G H After:A B C D * E F E F G H

The short arm of a chromosome is denoted by the letter and the long arm by the letter .