Exam 24: Genetics and Genomics

A multifactorial trait is determined by

In a simple dominant-recessive inheritance pattern, what is the chance of the offspring exhibiting the dominant trait if one parent is heterozygous and the other is homozygous recessive?

Observing a karyotype for a fetus, an obstetrician notices that for the 16ᵗʰ chromosome, there are 3 structures shown. What sort of chromosomal abnormality does this fetus have?

An autosomal condition affects only males.

A pedigree is a chart that aligns chromosome pairs by size.

Variable expressivity and pleiotropy can account for a disease that produces different intensities of symptoms or different symptoms among individuals.

A gene is

An allele that is not expressed in the heterozygous condition is

An inverted bell-shaped curve represents the distribution of phenotypes of a multifactorial trait in a population.

A multifactorial trait is determined by many environmental factors, but not necessarily genetic influences.

Which of the following prenatal tests is non-invasive?

In incomplete dominance,

Janet is homozygous dominant for the wild type allele of the gene that when mutant causes cystic fibrosis. Her brother Henry is a heterozygote. They both do not have the disease cystic fibrosis.

An autosomal dominant condition in a family will disappear if in any generation no one inherits the disease.

Chorionic villus sampling can be performed earlier in pregnancy than amniocentesis.

Studies have indicated a genetic link between a chromosome abnormality and acute myeloid leukemia, a deadly cancer affecting white blood cell production. Many sufferers of the cancer also possess monosomy 7, which is passed along generations in their families and also corresponds with the incidence of cancer in its members. What would you notice on a karyotype taken from a family with a trend of genetic-linked acute myeloid leukemia?

The chemical groups that binds to DNA causing genomic imprinting are

Chromosomes carry genes and genes carry genomes.

A person normally has two alleles of a gene because

A disorder that skips generations, affects both sexes, and is transmitted by parents who either have the condition or carry it is autosomal recessive.