Question 1

The ideal antimicrobial agent:

Accepted Answer

A) should be soluble in body fluids 
B) have an unpredictable toxicity 
C) should have interactions with other drugs or foods 
D) criteria are met by most antimicrobial agents 
A) should be soluble in body fluids 
B) have an unpredictable toxicity 
C) should have interactions with other drugs or foods 
D) criteria are met by most antimicrobial agents

Question 2

Purine or pyrimidine analogs:

Accepted Answer

A) act as antimetabolites 
B) inhibit ribosome function 
C) disrupt cell membrane function 
D) inhibit nucleic acid synthesis 
A) act as antimetabolites 
B) inhibit ribosome function 
C) disrupt cell membrane function 
D) inhibit nucleic acid synthesis

Question 3

What antibiotic kills bacteria by disrupting their cell membranes?

Accepted Answer

A) Erythromycin 
B) Rifampin 
C) Tetracycline 
D) Polymyxin B 
A) Erythromycin 
B) Rifampin 
C) Tetracycline 
D) Polymyxin B

Question 4

Cephalosporins are not _____.

Accepted Answer

A) wide spectrum antibiotics 
B) antibiotics with few side effects 
C) disruptors of cell membrane function 
D) used prophylactically in patients undergoing surgery 
A) wide spectrum antibiotics 
B) antibiotics with few side effects 
C) disruptors of cell membrane function 
D) used prophylactically in patients undergoing surgery

Question 5

Side effects due to antimicrobial agents may involve all of the following except:

Accepted Answer

A) allergic reactions 
B) anaphylactic shock 
C) disruption of microbial flora 
D) increased antibiotic susceptibility of replacement microflora 
A) allergic reactions 
B) anaphylactic shock 
C) disruption of microbial flora 
D) increased antibiotic susceptibility of replacement microflora

Question 6

Interferons and immunoenhancers:

Accepted Answer

A) are widely used to treat viruses 
B) cause no side effects 
C) include levamisole and inosiplex 
D) have been thoroughly researched 
A) are widely used to treat viruses 
B) cause no side effects 
C) include levamisole and inosiplex 
D) have been thoroughly researched

Question 7

Polypeptide antibiotics that act as detergents and distort bacterial cellular membranes do so by:

Accepted Answer

A) acting as antimetabolites 
B) inhibition of cell wall synthesis 
C) disruption of cell membrane integrity 
D) inhibition of nucleic acid synthesis 
A) acting as antimetabolites 
B) inhibition of cell wall synthesis 
C) disruption of cell membrane integrity 
D) inhibition of nucleic acid synthesis

Question 8

Antibiotics inhibit bacterial protein synthesis:

Accepted Answer

A) by disrupting cell membrane integrity 
B) by binding to 80S ribosomal subunits 
C) by interfering with the accurate reading of the mRNA message 
D) by binding to a 60S ribosomal subunit 
A) by disrupting cell membrane integrity 
B) by binding to 80S ribosomal subunits 
C) by interfering with the accurate reading of the mRNA message 
D) by binding to a 60S ribosomal subunit

Question 9

Mutation of DNA that produces an altered ribosome is an example of what type of bacterial resistance mechanism?

Accepted Answer

A) Alteration of a metabolic pathway 
B) Alteration of an enzyme 
C) Development of enzymes 
D) Alteration of target 
A) Alteration of a metabolic pathway 
B) Alteration of an enzyme 
C) Development of enzymes 
D) Alteration of target

Question 10

Metronidazole:

Accepted Answer

A) is effective against viruses 
B) has no side effects 
C) prevents overgrowth of Candida yeast infections 
D) is useful in the treatment of amoebas and Giardia 
A) is effective against viruses 
B) has no side effects 
C) prevents overgrowth of Candida yeast infections 
D) is useful in the treatment of amoebas and Giardia

Question 11

The sulfonamide antibiotics kill bacteria by _____.

Accepted Answer

A) interfering with cell wall synthesis 
B) disrupting folic acid metabolism 
C) reacting with bacterial cell membranes 
D) inhibiting bacterial motility 
A) interfering with cell wall synthesis 
B) disrupting folic acid metabolism 
C) reacting with bacterial cell membranes 
D) inhibiting bacterial motility

Question 12

Determining microbial sensitivity to an antimicrobial agent by using a filter paper soaked with the drug on a bacterial lawn on an agar plate is called:

Accepted Answer

A) the dilution method 
B) the disk diffusion method 
C) automated testing 
D) phage typing 
A) the dilution method 
B) the disk diffusion method 
C) automated testing 
D) phage typing

Question 13

Chloramphenicol,a bacteriostatic antimicrobial agent,is an inhibitor of:

Accepted Answer

A) nucleic acid synthesis 
B) cell wall synthesis 
C) cell membrane function 
D) protein synthesis 
A) nucleic acid synthesis 
B) cell wall synthesis 
C) cell membrane function 
D) protein synthesis

Question 14

A test to determine the effectiveness of an antimicrobial agent that uses growth of a test microorganism in patients' blood serum is the:

Accepted Answer

A) disk dilution method 
B) dilution method 
C) disk diffusion method 
D) serum killing power method 
A) disk dilution method 
B) dilution method 
C) disk diffusion method 
D) serum killing power method

Question 15

Tetracyclines interfere with _____.

Accepted Answer

A) the effectiveness of birth control pills 
B) transcription 
C) patients with heart defects 
D) metabolic reactions 
A) the effectiveness of birth control pills 
B) transcription 
C) patients with heart defects 
D) metabolic reactions

Question 16

What is happening in this image?

Accepted Answer

A) The individual is experiencing a side effect from taking an antifungal agent. 
B) The individual is experiencing a side effect from taking an antibiotic. 
C) The individual is experiencing a side effect from taking an antiviral agent. 
D) The individual is experiencing a side effect from taking an antiprotozoan agent. 
E) The individual is experiencing a side effect from taking an antihelminthic agent. 
A) The individual is experiencing a side effect from taking an antifungal agent. 
B) The individual is experiencing a side effect from taking an antibiotic. 
C) The individual is experiencing a side effect from taking an antiviral agent. 
D) The individual is experiencing a side effect from taking an antiprotozoan agent. 
E) The individual is experiencing a side effect from taking an antihelminthic agent.

Exam 13: Antimicrobial Therapy

The ideal antimicrobial agent:

Purine or pyrimidine analogs:

What antibiotic kills bacteria by disrupting their cell membranes?

Cephalosporins are not _____.

Side effects due to antimicrobial agents may involve all of the following except:

Interferons and immunoenhancers:

Polypeptide antibiotics that act as detergents and distort bacterial cellular membranes do so by:

Antibiotics inhibit bacterial protein synthesis:

Mutation of DNA that produces an altered ribosome is an example of what type of bacterial resistance mechanism?

Metronidazole:

The sulfonamide antibiotics kill bacteria by _____.

Determining microbial sensitivity to an antimicrobial agent by using a filter paper soaked with the drug on a bacterial lawn on an agar plate is called:

Chloramphenicol,a bacteriostatic antimicrobial agent,is an inhibitor of:

A test to determine the effectiveness of an antimicrobial agent that uses growth of a test microorganism in patients' blood serum is the:

Tetracyclines interfere with _____.

What is happening in this image?

Scope and History of Microbiology

Fundamentals of Chemistry

Microscopy and Staining

Characteristics of Prokaryotic and Eukaryotic Cells

Essential Concepts of Metabolism

Growth and Culturing of Bacteria

Microbial Genetics

Gene Transfer and Genetic Engineering

An Introduction to Taxonomy: the Bacteria

Viruses

Eukaryotic Microorganisms and Parasites

Sterilization and Disinfection

Host-Microbe Relationships and Disease Processes

Epidemiology and Nosocomial Infections

Innate Host Defenses

Immunology I: Basic Principles of Adaptive Immunity and Immunization

Immunology Ii: Immunological Disorders and Tests

Diseases of the Skin and Eyes; Wounds and Bites

Urogenital and Sexually Transmitted Diseases

Diseases of the Respiratory System

Oral and Gastrointestinal Diseases

Cardiovascular, lymphatic and Systemic Disease

Diseases of the Nervous System

Environmental Microbiology

Applied Microbiology

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