Question 1

Which of the antibiotics inhibit protein synthesis in susceptible bacteria?

Accepted Answer

A) Amikacin 
B) Tyrothricin 
C) Vancomycin 
D) Cephalexin 
A) Amikacin 
B) Tyrothricin 
C) Vancomycin 
D) Cephalexin A

Question 2

Selective toxicity:

Accepted Answer

A) harms the microbes without significantly harming the host. 
B) causes host damage without causing significant damage to the microbe. 
C) is the maximum tolerable dose of a drug per kilogram of body weight. 
D) is the same as the spectrum of activity for any given drug. 
A) harms the microbes without significantly harming the host. 
B) causes host damage without causing significant damage to the microbe. 
C) is the maximum tolerable dose of a drug per kilogram of body weight. 
D) is the same as the spectrum of activity for any given drug. A

Question 3

Which of following is not a way to limit the ability of microorganisms to acquire drug resistance?

Accepted Answer

A) High levels of antimicrobial agent in the patient 
B) Inhibiting growth of invading microbes so immune defenses can kill them 
C) Taking antibiotics until the patient feels better 
D) Taking two antibiotics synergistically 
A) High levels of antimicrobial agent in the patient 
B) Inhibiting growth of invading microbes so immune defenses can kill them 
C) Taking antibiotics until the patient feels better 
D) Taking two antibiotics synergistically C

Question 4

Any chemical substance used in medical practice is known as a/an:

Accepted Answer

A) antibiotic 
B) antimicrobial agent 
C) semi-synthetic drug 
D) chemotherapeutic agent 
A) antibiotic 
B) antimicrobial agent 
C) semi-synthetic drug 
D) chemotherapeutic agent

Question 5

Imidazoles and triazoles are antimicrobial agents that are effective:

Accepted Answer

A) bacteriostatic agents 
B) bactericidal agents 
C) antifungal agents 
D) antiviral agents 
A) bacteriostatic agents 
B) bactericidal agents 
C) antifungal agents 
D) antiviral agents

Question 6

Which of the following is not considered a mode of action by antimicrobial agents?

Accepted Answer

A) Inhibition of protein synthesis. 
B) Inhibition of cell wall synthesis. 
C) Inhibition of membrane permeability. 
D) Disruption of selective toxicity. 
A) Inhibition of protein synthesis. 
B) Inhibition of cell wall synthesis. 
C) Inhibition of membrane permeability. 
D) Disruption of selective toxicity.

Question 7

Paul Ehrlich:

Accepted Answer

A) coined the term chemotherapy 
B) discovered salvarsan in 1910 
C) discovered the antibiotic streptomycin 
D) accomplished two of the above. 
A) coined the term chemotherapy 
B) discovered salvarsan in 1910 
C) discovered the antibiotic streptomycin 
D) accomplished two of the above.

Question 8

Rimantadine is an effective antimicrobial agent against:

Accepted Answer

A) viruses 
B) protozoa 
C) bacteria 
D) fungi 
A) viruses 
B) protozoa 
C) bacteria 
D) fungi

Question 9

A special group of chemical substances that are used to treat diseases caused by microbes are called _____.

Accepted Answer

A) antibiotics 
B) synthetic drugs 
C) semi-synthetic drugs 
D) antimicrobial agents 
A) antibiotics 
B) synthetic drugs 
C) semi-synthetic drugs 
D) antimicrobial agents

Question 10

Describe the targets or action for three of the following: antifungal agents,antiviral agents,antiprotozoan agents and antihelminthic agents.

Accepted Answer

(i)Antifungal agents either increase pla

Question 11

The development of second-line and third-line antimicrobial agents demonstrates:

Accepted Answer

A) cross-resistance 
B) the effectiveness of first-line drugs 
C) an effective method to limit drug resistance 
D) the increasingly difficultly of treating drug resistant bacteria 
A) cross-resistance 
B) the effectiveness of first-line drugs 
C) an effective method to limit drug resistance 
D) the increasingly difficultly of treating drug resistant bacteria

Question 12

Rifampin:

Accepted Answer

A) inhibits RNA synthesis 
B) inhibits all nucleic acid synthesis 
C) disrupts of cell membrane function 
D) acts as an antimetabolite 
A) inhibits RNA synthesis 
B) inhibits all nucleic acid synthesis 
C) disrupts of cell membrane function 
D) acts as an antimetabolite

Question 13

A Candida albicans infection of the intestine,vagina or oral cavity is commonly treated with _____.

Accepted Answer

A) cefotaxime 
B) rifampin 
C) streptomycin 
D) nystatin 
A) cefotaxime 
B) rifampin 
C) streptomycin 
D) nystatin

Question 14

Antimetabolites include all of the following except:

Accepted Answer

A) trimethoprin 
B) isoniazid 
C) nitrofurantoin 
D) sulfanilamide 
A) trimethoprin 
B) isoniazid 
C) nitrofurantoin 
D) sulfanilamide

Question 15

Antibiotics that contain a beta-lactam ring:

Accepted Answer

A) interfere with peptidoglycan synthesis 
B) act as an antimetabolite 
C) bind to a bacterial RNA polymerase 
D) are erroneously incorporated into nucleic acids 
A) interfere with peptidoglycan synthesis 
B) act as an antimetabolite 
C) bind to a bacterial RNA polymerase 
D) are erroneously incorporated into nucleic acids

Question 16

Resistance of a microorganism to an antibiotic:

Accepted Answer

A) means that the microorganism is susceptible to the antibiotic 
B) can be acquired by genetic changes 
C) leads to a disruption of cell membrane function 
D) leads to a disruption of normal microflora 
A) means that the microorganism is susceptible to the antibiotic 
B) can be acquired by genetic changes 
C) leads to a disruption of cell membrane function 
D) leads to a disruption of normal microflora

Question 17

Which one of the following antimicrobial agents is an inhibitor of cell wall synthesis?

Accepted Answer

A) Tetracycline 
B) Carbapenems 
C) Chloramphenicol 
D) Erythromycin 
A) Tetracycline 
B) Carbapenems 
C) Chloramphenicol 
D) Erythromycin

Question 18

Examples of antiviral agents include all of the following agents except:

Accepted Answer

A) acyclovir 
B) ribavirin 
C) quinine 
D) zidovudine (AZT) 
A) acyclovir 
B) ribavirin 
C) quinine 
D) zidovudine (AZT)

Question 19

Mechanisms of bacterial resistance to antimicrobial agents include all of the following except:

Accepted Answer

A) alteration of ribosomes 
B) alteration of an enzyme 
C) development of enzymes 
D) alteration of normal microflora 
A) alteration of ribosomes 
B) alteration of an enzyme 
C) development of enzymes 
D) alteration of normal microflora

Question 20

Select the incorrect statement.

Accepted Answer

A) Chloramphenicol is responsible for the staining of these teeth. 
B) One can expect the baby teeth and adult teeth to be affected by the antibiotic taken by this individual if consumed by their pregnant mother during the last trimester. 
C) Tetracycline leads to abnormal bone formation as observed in this image. 
D) All of these statements are correct. 
A) Chloramphenicol is responsible for the staining of these teeth. 
B) One can expect the baby teeth and adult teeth to be affected by the antibiotic taken by this individual if consumed by their pregnant mother during the last trimester. 
C) Tetracycline leads to abnormal bone formation as observed in this image. 
D) All of these statements are correct.

Exam 13: Antimicrobial Therapy

Which of the antibiotics inhibit protein synthesis in susceptible bacteria?

Selective toxicity:

Which of following is not a way to limit the ability of microorganisms to acquire drug resistance?

Any chemical substance used in medical practice is known as a/an:

Imidazoles and triazoles are antimicrobial agents that are effective:

Which of the following is not considered a mode of action by antimicrobial agents?

Paul Ehrlich:

Rimantadine is an effective antimicrobial agent against:

A special group of chemical substances that are used to treat diseases caused by microbes are called _____.

Describe the targets or action for three of the following: antifungal agents,antiviral agents,antiprotozoan agents and antihelminthic agents.

The development of second-line and third-line antimicrobial agents demonstrates:

Rifampin:

A Candida albicans infection of the intestine,vagina or oral cavity is commonly treated with _____.

Antimetabolites include all of the following except:

Antibiotics that contain a beta-lactam ring:

Resistance of a microorganism to an antibiotic:

Which one of the following antimicrobial agents is an inhibitor of cell wall synthesis?

Examples of antiviral agents include all of the following agents except:

Mechanisms of bacterial resistance to antimicrobial agents include all of the following except:

Select the incorrect statement.

Scope and History of Microbiology

Fundamentals of Chemistry

Microscopy and Staining

Characteristics of Prokaryotic and Eukaryotic Cells

Essential Concepts of Metabolism

Growth and Culturing of Bacteria

Microbial Genetics

Gene Transfer and Genetic Engineering

An Introduction to Taxonomy: the Bacteria

Viruses

Eukaryotic Microorganisms and Parasites

Sterilization and Disinfection

Host-Microbe Relationships and Disease Processes

Epidemiology and Nosocomial Infections

Innate Host Defenses

Immunology I: Basic Principles of Adaptive Immunity and Immunization

Immunology Ii: Immunological Disorders and Tests

Diseases of the Skin and Eyes; Wounds and Bites

Urogenital and Sexually Transmitted Diseases

Diseases of the Respiratory System

Oral and Gastrointestinal Diseases

Cardiovascular, lymphatic and Systemic Disease

Diseases of the Nervous System

Environmental Microbiology

Applied Microbiology

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