Question 1

MATCHING
Match the following drugs with their classes.
-Nonpolarizing neuromuscular drugs

Accepted Answer

A) Neostigmine 
B) Rocuronium 
C) Succinylcholine 
A) Neostigmine 
B) Rocuronium 
C) Succinylcholine B

Question 2

Drugs that decrease ACh release or deplete the neuron of ACh will also cause _____ of muscles.

Accepted Answer

A) contraction 
B) stiffening 
C) relaxation 
D) tremor 
A) contraction 
B) stiffening 
C) relaxation 
D) tremor C

Question 3

The process of neuromuscular transmission begins with the release of _____ from vesicles located in the motor neuron endplate.

Accepted Answer

A) acetylcholine (ACh) 
B) dopamine (D
A)  
C) norepinephrine (N
E)  
D) g-aminobutyric acid (GAB
A)  
A) acetylcholine (ACh) 
B) dopamine (D
A)  
C) norepinephrine (N
E)  
D) g-aminobutyric acid (GAB
A)  A

Question 4

How do neuromuscular blocking drugs work to cause muscle relaxation?

Accepted Answer

A) They block calcium channels,increasing the amount of ACh produced,which causes relaxation. 
B) They increase the amount of inhibitory neurotransmitters. 
C) They block all transmissions of excitement. 
D) They increase the amount of inactivated ACh receptor sites. 
A) They block calcium channels,increasing the amount of ACh produced,which causes relaxation. 
B) They increase the amount of inhibitory neurotransmitters. 
C) They block all transmissions of excitement. 
D) They increase the amount of inactivated ACh receptor sites.

Question 5

After dilution,succinylcholine is stable at room temperature for _____ day(s).

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
A) 1 
B) 2 
C) 3 
D) 4

Question 6

_____ is the only drug in the depolarizing blocker class.

Accepted Answer

A) Ethosuximide 
B) Succinylcholine 
C) Acetylcholine 
D) Vecuronium 
A) Ethosuximide 
B) Succinylcholine 
C) Acetylcholine 
D) Vecuronium

Question 7

With the exception of mivacurium,neuromuscular blocking agents should be stored _____.

Accepted Answer

A) at room temperature 
B) in the refrigerator 
C) in the freezer 
D) in a warmer 
A) at room temperature 
B) in the refrigerator 
C) in the freezer 
D) in a warmer

Question 8

Most neuromuscular blocking drugs are poorly absorbed from the gastrointestinal tract;therefore,they are administered _____.

Accepted Answer

A) topically 
B) parenterally 
C) transdermally 
D) orally 
A) topically 
B) parenterally 
C) transdermally 
D) orally

Question 9

MATCHING
Match the following drugs with their classes.
-Drug used to reverse the effects of neuromuscular blocking drugs

Accepted Answer

A) Neostigmine 
B) Rocuronium 
C) Succinylcholine 
A) Neostigmine 
B) Rocuronium 
C) Succinylcholine

Question 10

MATCHING
Match the following drugs with their classes.
-Depolarizing neuromuscular blocking drugs

Accepted Answer

A) Neostigmine 
B) Rocuronium 
C) Succinylcholine 
A) Neostigmine 
B) Rocuronium 
C) Succinylcholine

Question 11

After dilution,atracurium should be infused within _____ hours.

Accepted Answer

A) 4 
B) 8 
C) 12 
D) 24 
A) 4 
B) 8 
C) 12 
D) 24

Question 12

Which of the following uses of onabotulinumtoxin A is not U.S.Food and Drug Administration (FDA)approved?

Accepted Answer

A) Spasticity 
B) Treatment of excessive sweating 
C) Treatment of uncontrollable blinking 
D) Occasional migraines 
A) Spasticity 
B) Treatment of excessive sweating 
C) Treatment of uncontrollable blinking 
D) Occasional migraines

Question 13

How does blocking calcium channels cause muscle relaxation?

Accepted Answer

A) Permits the blockage of nerve transmissions between the motor endplate and skeletal muscle receptors 
B) Blocks the release of ACh 
C) Promotes the binding of GABA at the neuromuscular junction,decreasing excitatory messages 
D) Allows for nerve transmissions to be blocked between the spinal cord and muscles 
A) Permits the blockage of nerve transmissions between the motor endplate and skeletal muscle receptors 
B) Blocks the release of ACh 
C) Promotes the binding of GABA at the neuromuscular junction,decreasing excitatory messages 
D) Allows for nerve transmissions to be blocked between the spinal cord and muscles

Question 14

Which of the following is a nondepolarizing neuromuscular blocker?

Accepted Answer

A) Edrophonium 
B) Pyridostigmine 
C) Succinylcholine 
D) Vecuronium 
A) Edrophonium 
B) Pyridostigmine 
C) Succinylcholine 
D) Vecuronium

Question 15

Depolarizing neuromuscular drugs are _____ at _____ receptors.

Accepted Answer

A) agonists,nicotinic 
B) adrenergic antagonists,muscarinic 
C) adrenergic agonists,muscarinic 
D) antagonists,nicotinic 
A) agonists,nicotinic 
B) adrenergic antagonists,muscarinic 
C) adrenergic agonists,muscarinic 
D) antagonists,nicotinic

Question 16

Which of the following is not an adverse reaction of administration of botulinum toxin type A injections?

Accepted Answer

A) Blepharoptosis 
B) Muscle weakness 
C) Blepharospasms 
D) Headache 
A) Blepharoptosis 
B) Muscle weakness 
C) Blepharospasms 
D) Headache

Question 17

An example of a drug or substance that decreases ACh release is _____.

Accepted Answer

A) potassium 
B) sodium 
C) calcium 
D) magnesium 
A) potassium 
B) sodium 
C) calcium 
D) magnesium

Question 18

Which of the following can inhibit the action of ACh at the neuromuscular junction to reverse neuromuscular blockade?

Accepted Answer

A) Rocuronium 
B) Succinylcholine 
C) Pancuronium 
D) Edrophonium 
A) Rocuronium 
B) Succinylcholine 
C) Pancuronium 
D) Edrophonium

Question 19

What drugs should be administered with neuromuscular blocking drugs during surgery?

Accepted Answer

A) Antianxiety 
B) Analgesics 
C) Central nervous system depressants 
D) Beta blockers 
A) Antianxiety 
B) Analgesics 
C) Central nervous system depressants 
D) Beta blockers

Question 20

Why do nondepolarizing drugs have a longer duration of action than depolarizing drugs?

Accepted Answer

A) Nondepolarizing drugs have a higher affinity to ACh receptors. 
B) The half-life is longer for nondepolarizing drugs. 
C) Nondepolarizing drugs are not broken down by acetylcholinesterase. 
D) Depolarizing drugs are not as easily absorbed as nondepolarizing drugs. 
A) Nondepolarizing drugs have a higher affinity to ACh receptors. 
B) The half-life is longer for nondepolarizing drugs. 
C) Nondepolarizing drugs are not broken down by acetylcholinesterase. 
D) Depolarizing drugs are not as easily absorbed as nondepolarizing drugs.

Exam 13: Neuromuscular Blockade

MATCHING Match the following drugs with their classes. -Nonpolarizing neuromuscular drugs

Drugs that decrease ACh release or deplete the neuron of ACh will also cause _____ of muscles.

The process of neuromuscular transmission begins with the release of _____ from vesicles located in the motor neuron endplate.

How do neuromuscular blocking drugs work to cause muscle relaxation?

After dilution,succinylcholine is stable at room temperature for _____ day(s).

_____ is the only drug in the depolarizing blocker class.

With the exception of mivacurium,neuromuscular blocking agents should be stored _____.

Most neuromuscular blocking drugs are poorly absorbed from the gastrointestinal tract;therefore,they are administered _____.

MATCHING Match the following drugs with their classes. -Drug used to reverse the effects of neuromuscular blocking drugs

MATCHING Match the following drugs with their classes. -Depolarizing neuromuscular blocking drugs

After dilution,atracurium should be infused within _____ hours.

Which of the following uses of onabotulinumtoxin A is not U.S.Food and Drug Administration (FDA)approved?

How does blocking calcium channels cause muscle relaxation?

Which of the following is a nondepolarizing neuromuscular blocker?

Depolarizing neuromuscular drugs are _____ at _____ receptors.

Which of the following is not an adverse reaction of administration of botulinum toxin type A injections?

An example of a drug or substance that decreases ACh release is _____.

Which of the following can inhibit the action of ACh at the neuromuscular junction to reverse neuromuscular blockade?

What drugs should be administered with neuromuscular blocking drugs during surgery?

Why do nondepolarizing drugs have a longer duration of action than depolarizing drugs?

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Psychoses

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Seizure Disorders

Treatment of Pain and Migraine Headache

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Filters

Depolarizing neuromuscular drugs are _ at _ receptors.