Question 1

Antagonizing which receptors is useful in the treatment of negative symptoms of schizophrenia?

Accepted Answer

A) DA 
B) Glutamate 
C) 5-HT 
D) Neurotensin 
A) DA 
B) Glutamate 
C) 5-HT 
D) Neurotensin C

Question 2

Persons diagnosed with schizophrenia often see visions or hear voices that cannot be seen or heard by others.

Accepted Answer

A) True 
 B)False  True

Question 3

Why would a slow-release depot formulation be preferred when treating schizophrenia?

Accepted Answer

A) Eliminates the side effects associated with schizophrenia 
B) Does not interfere with the metabolism of other drugs 
C) Allows for once-a-day dosing because of its slow-release formulation 
D) To allow for infrequent administration of the medication for maintenance therapy 
A) Eliminates the side effects associated with schizophrenia 
B) Does not interfere with the metabolism of other drugs 
C) Allows for once-a-day dosing because of its slow-release formulation 
D) To allow for infrequent administration of the medication for maintenance therapy D

Question 4

What neurotransmitter is not associated with schizophrenia?

Accepted Answer

A) Acetylcholine 
B) Glutamate 
C) Cholecystokinin 
D) Serotonin (5-hydroxytryptamine [5-HT]) 
A) Acetylcholine 
B) Glutamate 
C) Cholecystokinin 
D) Serotonin (5-hydroxytryptamine [5-HT])

Question 5

MATCHING
Match the following generic drug names with their brand name.
-Risperidone

Accepted Answer

A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril 
A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril

Question 6

Traditional neuroleptics block DA at postsynaptic receptor sites.

Accepted Answer

A) True 
 B)False

Question 7

Which of the following is thought to influence the development of schizophrenia?

Accepted Answer

A) Parkinson's disease 
B) Drug abuse 
C) Dementia 
D) Bipolar disorder 
A) Parkinson's disease 
B) Drug abuse 
C) Dementia 
D) Bipolar disorder

Question 8

_____ is the most significant neurotransmitter target when treating schizophrenia.

Accepted Answer

A) GABA 
B) 5-HT 
C) Glutamate 
D) DA 
A) GABA 
B) 5-HT 
C) Glutamate 
D) DA

Question 9

Not all neuroleptic agents bind to dopamine (DA)receptors.

Accepted Answer

A) True 
 B)False

Question 10

MATCHING
Match the following generic drug names with their brand name.
-Quetiapine

Accepted Answer

A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril 
A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril

Question 11

Neuroleptic malignant syndrome (NMS)is a life-threatening side effect of neuroleptic administration.

Accepted Answer

A) True 
 B)False

Question 12

Onset of schizophrenia typically occurs _____.

Accepted Answer

A) after age 45 
B) before age 10 
C) in the late teens 
D) in the late 30s 
A) after age 45 
B) before age 10 
C) in the late teens 
D) in the late 30s

Question 13

Which of the following is not used in the treatment and management of schizophrenia and bipolar disorder?

Accepted Answer

A) Thienobenzodiazepines 
B) Tranylcypromine 
C) Risperidone 
D) Quetiapine 
A) Thienobenzodiazepines 
B) Tranylcypromine 
C) Risperidone 
D) Quetiapine

Question 14

People diagnosed with schizophrenia often exhibit these types of symptoms except _____.

Accepted Answer

A) negative 
B) positive 
C) cognitive 
D) neutral 
A) negative 
B) positive 
C) cognitive 
D) neutral

Question 15

____ is classified as the prototype for low-potency neuroleptics.

Accepted Answer

A) Promethazine 
B) Perphenazine 
C) Chlorpromazine 
D) Compazine 
A) Promethazine 
B) Perphenazine 
C) Chlorpromazine 
D) Compazine

Question 16

Schizophrenia does not run in families.

Accepted Answer

A) True 
 B)False

Question 17

Which of the following is a side effect due to histaminergic (H₁)blockade caused by neuroleptic treatment?

Accepted Answer

A) Sedation 
B) Weight loss 
C) Urinary retention 
D) Postural hypotension 
A) Sedation 
B) Weight loss 
C) Urinary retention 
D) Postural hypotension

Question 18

MATCHING
Match the following generic drug names with their brand name.
-Ziprasidone

Accepted Answer

A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril 
A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril

Question 19

MATCHING
Match the following generic drug names with their brand name.
-Clozapine

Accepted Answer

A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril 
A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril

Question 20

MATCHING
Match the following generic drug names with their brand name.
-Loxapine

Accepted Answer

A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril 
A) Risperdal 
B) Seroquel 
C) Geodon 
D) Loxitane 
E) Clozaril

Exam 7: Treatment of Schizophrenia and Psychoses

Antagonizing which receptors is useful in the treatment of negative symptoms of schizophrenia?

Persons diagnosed with schizophrenia often see visions or hear voices that cannot be seen or heard by others.

Why would a slow-release depot formulation be preferred when treating schizophrenia?

What neurotransmitter is not associated with schizophrenia?

MATCHING Match the following generic drug names with their brand name. -Risperidone

Traditional neuroleptics block DA at postsynaptic receptor sites.

Which of the following is thought to influence the development of schizophrenia?

_____ is the most significant neurotransmitter target when treating schizophrenia.

Not all neuroleptic agents bind to dopamine (DA)receptors.

MATCHING Match the following generic drug names with their brand name. -Quetiapine

Neuroleptic malignant syndrome (NMS)is a life-threatening side effect of neuroleptic administration.

Onset of schizophrenia typically occurs _____.

Which of the following is not used in the treatment and management of schizophrenia and bipolar disorder?

People diagnosed with schizophrenia often exhibit these types of symptoms except _____.

____ is classified as the prototype for low-potency neuroleptics.

Schizophrenia does not run in families.

Which of the following is a side effect due to histaminergic (H₁)blockade caused by neuroleptic treatment?

MATCHING Match the following generic drug names with their brand name. -Ziprasidone

MATCHING Match the following generic drug names with their brand name. -Clozapine

MATCHING Match the following generic drug names with their brand name. -Loxapine

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Seizure Disorders

Treatment of Pain and Migraine Headache

Treatment of Alzheimers Disease

Treatment of Sleep Disorders and Attention-Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

Treatment of Autoimmune Diseases That Affect the Musculoskeletal System

Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

Treatment of Glaucoma

Treatment of Disorders of the Ear

Treatment of Ophthalmic and Otic Infections

Treatment of Angina

Treatment of Hypertension

Treatment of Heart Failure

Treatment of Myocardial Infarction and Stroke

Treatment of Arrhythmia

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Treatment of Asthma and Chronic Obstructive Pulmonary Disease

Treatment of Allergies

Treatment of Prostate Disease and Erectile Dysfunction

Treatment of Fluid and Electrolyte Disorders

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Drugs That Affect the Reproductive System

Treatment of Bacterial Infection

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Vaccines, Immunomodulators, and Immunosuppressants

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