Question 1

MATCHING
Match the following trade and generic drug names.
-Zenapax

Accepted Answer

A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine 
A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine D

Question 2

Which of the following would be the least affected by a breach in the "cold chain"?

Accepted Answer

A) Biological solutions 
B) Vaccines 
C) Dry powders 
D) Biological suspensions 
A) Biological solutions 
B) Vaccines 
C) Dry powders 
D) Biological suspensions C

Question 3

Which of the following macrolide immunosuppressants is indicated to prevent transplant rejections?

Accepted Answer

A) Everolimus 
B) Temsirolimus 
C) Belatacept 
D) Pimecrolimus 
A) Everolimus 
B) Temsirolimus 
C) Belatacept 
D) Pimecrolimus A

Question 4

Which of the following drugs works by suppressing cell destruction in graft-versus-host reactions?

Accepted Answer

A) Tacrolimus 
B) Cyclosporine 
C) Atgam 
D) CellCept 
A) Tacrolimus 
B) Cyclosporine 
C) Atgam 
D) CellCept

Question 5

Antithymocyte globulin (ATG)is administered primarily to _____.

Accepted Answer

A) reduce rejection associated with organ and bone marrow transplantation. 
B) boost the immune system of the immunosuppressed patient 
C) provide protection against infections attacking the immunosuppressed patient 
D) treat eczema 
A) reduce rejection associated with organ and bone marrow transplantation. 
B) boost the immune system of the immunosuppressed patient 
C) provide protection against infections attacking the immunosuppressed patient 
D) treat eczema

Question 6

MATCHING
Match the following trade and generic drug names.
-Prograf

Accepted Answer

A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine 
A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine

Question 7

A person taking belatacept should not receive which of the following vaccines?

Accepted Answer

A) Hepatitis A 
B) Tetanus 
C) Rubella 
D) Meningococcal 
A) Hepatitis A 
B) Tetanus 
C) Rubella 
D) Meningococcal

Question 8

Mycophenolic acid is an immunosuppressive agent that inhibits the enzyme required for synthesis of purines needed for _____.

Accepted Answer

A) T-cell lymphocytes 
B) T-cell and B-cell proliferation 
C) B-cell antibodies 
D) inhibition of CYP450 microsomal pathways 
A) T-cell lymphocytes 
B) T-cell and B-cell proliferation 
C) B-cell antibodies 
D) inhibition of CYP450 microsomal pathways

Question 9

Which of the following is not an example of a live vaccine?

Accepted Answer

A) Polio 
B) Mumps 
C) Tetanus 
D) Rubella 
A) Polio 
B) Mumps 
C) Tetanus 
D) Rubella

Question 10

The flu vaccine must be reformulated every _____.

Accepted Answer

A) 6 months 
B) year 
C) 24 months 
D) 5 years 
A) 6 months 
B) year 
C) 24 months 
D) 5 years

Question 11

MATCHING
Match the following trade and generic drug names.
-CellCept

Accepted Answer

A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine 
A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine

Question 12

MATCHING
Match the following trade and generic drug names.
-Sandimmune

Accepted Answer

A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine 
A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine

Question 13

Tetanus and diphtheria are examples of _____ vaccines.

Accepted Answer

A) conjugated 
B) live,attenuated 
C) toxoid 
D) inactivated,killed 
A) conjugated 
B) live,attenuated 
C) toxoid 
D) inactivated,killed

Question 14

An example of a conjugate vaccine is _____.

Accepted Answer

A) Haemophilus influenzae type B (Hib) 
B) flu 
C) mumps 
D) varicella 
A) Haemophilus influenzae type B (Hib) 
B) flu 
C) mumps 
D) varicella

Question 15

The immunomodulator basiliximab is used to _____.

Accepted Answer

A) treat advanced renal cancer 
B) block transcription of cytokines and interleukins 
C) encourage T-cell proliferation 
D) prolong the life of transplanted organs 
A) treat advanced renal cancer 
B) block transcription of cytokines and interleukins 
C) encourage T-cell proliferation 
D) prolong the life of transplanted organs

Question 16

MATCHING
Match the following trade and generic drug names.
-Elidel

Accepted Answer

A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine 
A) Mycophenolate mofetil 
B) Pimecrolimus 
C) Tacrolimus 
D) Daclizumab 
E) Cyclosporine

Question 17

Which of the following classifications of drugs are not categorized as immunopharmacologicals?

Accepted Answer

A) Corticosteroids 
B) Antineoplastics 
C) Antivirals 
D) Cytokine inhibitors 
A) Corticosteroids 
B) Antineoplastics 
C) Antivirals 
D) Cytokine inhibitors

Question 18

Which of the following entities must keep the cold chain for vaccines and immunologicals unbroken?

Accepted Answer

A) Manufacturer 
B) Pharmacy 
C) Physician's office 
D) All of the above 
A) Manufacturer 
B) Pharmacy 
C) Physician's office 
D) All of the above

Question 19

Sirolimus interferes with a key enzyme that regulates the second phase of T-cell activation and proliferation and decreases levels of all of the following immunoglobulins except _____.

Accepted Answer

A) IgM 
B) IgG 
C) IgD 
D) IgA 
A) IgM 
B) IgG 
C) IgD 
D) IgA

Question 20

The temperature that must be maintained for an uninterrupted cold chain from the manufacturer to its final destination is _____.

Accepted Answer

A) 2° to 6° F 
B) 2° to 8° C 
C) 32° to 59° C 
D) 59° to 86° F 
A) 2° to 6° F 
B) 2° to 8° C 
C) 32° to 59° C 
D) 59° to 86° F

Exam 38: Vaccines, Immunomodulators, and Immunosuppressants

MATCHING Match the following trade and generic drug names. -Zenapax

Which of the following would be the least affected by a breach in the "cold chain"?

Which of the following macrolide immunosuppressants is indicated to prevent transplant rejections?

Which of the following drugs works by suppressing cell destruction in graft-versus-host reactions?

Antithymocyte globulin (ATG)is administered primarily to _____.

MATCHING Match the following trade and generic drug names. -Prograf

A person taking belatacept should not receive which of the following vaccines?

Mycophenolic acid is an immunosuppressive agent that inhibits the enzyme required for synthesis of purines needed for _____.

Which of the following is not an example of a live vaccine?

The flu vaccine must be reformulated every _____.

MATCHING Match the following trade and generic drug names. -CellCept

MATCHING Match the following trade and generic drug names. -Sandimmune

Tetanus and diphtheria are examples of _____ vaccines.

An example of a conjugate vaccine is _____.

The immunomodulator basiliximab is used to _____.

MATCHING Match the following trade and generic drug names. -Elidel

Which of the following classifications of drugs are not categorized as immunopharmacologicals?

Which of the following entities must keep the cold chain for vaccines and immunologicals unbroken?

Sirolimus interferes with a key enzyme that regulates the second phase of T-cell activation and proliferation and decreases levels of all of the following immunoglobulins except _____.

The temperature that must be maintained for an uninterrupted cold chain from the manufacturer to its final destination is _____.

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