Question 1

How does Alzheimer's disease develop?

Accepted Answer

A) Cholinergic nerve cells die in the brain,decreasing the ability to absorb,process,and use information. 
B) The hypothalamus becomes blocked by beta amyloids and twisted fibers,blocking transmission signals. 
C) Adrenergic nerves become blocked by plaques and tangles,blocking transmission between the neurons. 
D) The frontal cortex begins to shrink,losing its ability to think and function. 
A) Cholinergic nerve cells die in the brain,decreasing the ability to absorb,process,and use information. 
B) The hypothalamus becomes blocked by beta amyloids and twisted fibers,blocking transmission signals. 
C) Adrenergic nerves become blocked by plaques and tangles,blocking transmission between the neurons. 
D) The frontal cortex begins to shrink,losing its ability to think and function. A

Question 2

MATCHING
Match the following trade and generic drug names.
-Aricept

Accepted Answer

A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine 
A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine B

Question 3

How do acetylcholinesterase (AChE)inhibitors help treat Alzheimer's disease?

Accepted Answer

A) They help form a protective lining around muscarinic receptors to only allow binding of ACh. 
B) They increase levels of ACh by inhibiting AChE. 
C) They help protect any remaining cognition and memory by antagonizing the receptors involved in memory. 
D) They decrease levels of ACh by allowing AChE to metabolize ACh,thereby reducing the levels in the brain. 
A) They help form a protective lining around muscarinic receptors to only allow binding of ACh. 
B) They increase levels of ACh by inhibiting AChE. 
C) They help protect any remaining cognition and memory by antagonizing the receptors involved in memory. 
D) They decrease levels of ACh by allowing AChE to metabolize ACh,thereby reducing the levels in the brain. B

Question 4

_____ is a neurodegenerative disease that causes memory loss,behavioral changes,and immobility.

Accepted Answer

A) Dementia 
B) Multiple sclerosis 
C) Cerebrovascular accident 
D) Alzheimer's disease 
A) Dementia 
B) Multiple sclerosis 
C) Cerebrovascular accident 
D) Alzheimer's disease

Question 5

Which of the following is a modifiable risk for Alzheimer's disease?

Accepted Answer

A) Alcohol consumption 
B) Smoking 
C) Obesity 
D) Add weight training to exercise regimen 
A) Alcohol consumption 
B) Smoking 
C) Obesity 
D) Add weight training to exercise regimen

Question 6

Alzheimer's disease causes damage to the _____,the part of the brain that is involved in memory.

Accepted Answer

A) cerebellum 
B) hippocampus 
C) medulla 
D) thalamus 
A) cerebellum 
B) hippocampus 
C) medulla 
D) thalamus

Question 7

Which of the following is not a normal part of the aging process?

Accepted Answer

A) Urinary incontinence 
B) Aching joints 
C) Dementia 
D) Minor forgetfulness 
A) Urinary incontinence 
B) Aching joints 
C) Dementia 
D) Minor forgetfulness

Question 8

Which drug may slow the progression of Alzheimer's disease if administered early enough?

Accepted Answer

A) Memantine 
B) Donepezil 
C) Galantamine 
D) Rivastigmine 
A) Memantine 
B) Donepezil 
C) Galantamine 
D) Rivastigmine

Question 9

MATCHING
Match the following trade and generic drug names.
-Reminyl

Accepted Answer

A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine 
A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine

Question 10

What role do the CLU and CRI genes play in the development of Alzheimer's disease?

Accepted Answer

A) They allow for transmission through tangles in the brain. 
B) They help clear plaques out of the brain. 
C) They allow acetylcholine (Ach)to bind to receptors in the brain. 
D) They prevent the onset of Alzheimer's disease. 
A) They allow for transmission through tangles in the brain. 
B) They help clear plaques out of the brain. 
C) They allow acetylcholine (Ach)to bind to receptors in the brain. 
D) They prevent the onset of Alzheimer's disease.

Question 11

Which drug can be used as an AChE inhibitor and also slightly increase glutamate activity?

Accepted Answer

A) Galantamine 
B) Donepezil 
C) Memantine 
D) Rivastigmine 
A) Galantamine 
B) Donepezil 
C) Memantine 
D) Rivastigmine

Question 12

Reduced function of the _____ receptors is responsible for impaired memory.

Accepted Answer

A) dopamine 
B) adrenergic 
C) muscarinic 
D) nicotinic 
A) dopamine 
B) adrenergic 
C) muscarinic 
D) nicotinic

Question 13

Which of the following is used to block the actions of glutamate to help protect further damage to the neuron?

Accepted Answer

A) Donepezil 
B) Rivastigmine 
C) Galantamine 
D) Memantine 
A) Donepezil 
B) Rivastigmine 
C) Galantamine 
D) Memantine

Question 14

The neurotransmitter that plays a significant role in Alzheimer's disease is _____.

Accepted Answer

A) dopamine 
B) norepinephrine 
C) ACh 
D) serotonin 
A) dopamine 
B) norepinephrine 
C) ACh 
D) serotonin

Question 15

In what stage of Alzheimer's disease may a person become confused and wander,unable to find their way back?

Accepted Answer

A) Pre-Alzheimer's stage 
B) Early stage 
C) Moderate stage 
D) Late stage 
A) Pre-Alzheimer's stage 
B) Early stage 
C) Moderate stage 
D) Late stage

Question 16

In the future,which of the following vitamins could possibly be used to prevent Alzheimer's disease after adequate studies have been completed and it has been proven effective?

Accepted Answer

A) A 
B) B6 
C) D 
D) E 
A) A 
B) B6 
C) D 
D) E

Question 17

MATCHING
Match the following trade and generic drug names.
-Exelon

Accepted Answer

A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine 
A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine

Question 18

MATCHING
Match the following trade and generic drug names.
-Namenda

Accepted Answer

A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine 
A) Memantine 
B) Donepezil 
C) Rivastigmine 
D) Galantamine

Question 19

_____ could be added to the diet of those with Alzheimer's and heart disease to help decrease the progression of Alzheimer's disease.

Accepted Answer

A) Flaxseed 
B) Olive oil 
C) Fiber 
D) St.John's wort 
A) Flaxseed 
B) Olive oil 
C) Fiber 
D) St.John's wort

Question 20

Which of the following conditions is sometimes comorbid with Alzheimer's disease and can speed its progression as a result of its effects on the parasympathetic system?

Accepted Answer

A) High blood pressure 
B) Parkinson's disease 
C) Diabetes 
D) Dementia 
A) High blood pressure 
B) Parkinson's disease 
C) Diabetes 
D) Dementia

Exam 11: Treatment of Alzheimers Disease

How does Alzheimer's disease develop?

MATCHING Match the following trade and generic drug names. -Aricept

How do acetylcholinesterase (AChE)inhibitors help treat Alzheimer's disease?

_____ is a neurodegenerative disease that causes memory loss,behavioral changes,and immobility.

Which of the following is a modifiable risk for Alzheimer's disease?

Alzheimer's disease causes damage to the _____,the part of the brain that is involved in memory.

Which of the following is not a normal part of the aging process?

Which drug may slow the progression of Alzheimer's disease if administered early enough?

MATCHING Match the following trade and generic drug names. -Reminyl

What role do the CLU and CRI genes play in the development of Alzheimer's disease?

Which drug can be used as an AChE inhibitor and also slightly increase glutamate activity?

Reduced function of the _____ receptors is responsible for impaired memory.

Which of the following is used to block the actions of glutamate to help protect further damage to the neuron?

The neurotransmitter that plays a significant role in Alzheimer's disease is _____.

In what stage of Alzheimer's disease may a person become confused and wander,unable to find their way back?

In the future,which of the following vitamins could possibly be used to prevent Alzheimer's disease after adequate studies have been completed and it has been proven effective?

MATCHING Match the following trade and generic drug names. -Exelon

MATCHING Match the following trade and generic drug names. -Namenda

_____ could be added to the diet of those with Alzheimer's and heart disease to help decrease the progression of Alzheimer's disease.

Which of the following conditions is sometimes comorbid with Alzheimer's disease and can speed its progression as a result of its effects on the parasympathetic system?

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Psychoses

Treatment of Parkinsons Disease and Huntingtons Disease

Treatment of Seizure Disorders

Treatment of Pain and Migraine Headache

Treatment of Sleep Disorders and Attention-Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

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Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

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