Question 1

Why would Levodopa be administered instead of oral DA to help treat Parkinson's disease?

Accepted Answer

A) Bioavailability of oral DA is limited because it does not cross the blood-brain barrier. 
B) DA would be rapidly metabolized by catechol-O-methyltransferase (COMT)in the gastrointestinal (GI)tract,reducing bioavailability. 
C) Levodopa causes less adverse effects than oral DA would. 
D) Levodopa and oral DA are typically prescribed equally to treat Parkinson's disease. 
A) Bioavailability of oral DA is limited because it does not cross the blood-brain barrier. 
B) DA would be rapidly metabolized by catechol-O-methyltransferase (COMT)in the gastrointestinal (GI)tract,reducing bioavailability. 
C) Levodopa causes less adverse effects than oral DA would. 
D) Levodopa and oral DA are typically prescribed equally to treat Parkinson's disease.

Question 2

Which of the following would be used to block DA receptors?

Accepted Answer

A) Benztropine 
B) Selegiline 
C) Haloperidol 
D) Pramipexole 
A) Benztropine 
B) Selegiline 
C) Haloperidol 
D) Pramipexole

Question 3

What is thought to be a rare cause of Parkinson's disease in person's under 40 years old?

Accepted Answer

A) Inheritance of the chromosome 4 gene 
B) Use of illegal synthesized drugs 
C) Exposure to pesticides 
D) Contraction of syphilis 
A) Inheritance of the chromosome 4 gene 
B) Use of illegal synthesized drugs 
C) Exposure to pesticides 
D) Contraction of syphilis

Question 4

_____ can be administered to lessen drug-induced extrapyramidal symptoms.

Accepted Answer

A) Anticholinergics 
B) Dopaminergics 
C) DA antagonists 
D) Cholinergics 
A) Anticholinergics 
B) Dopaminergics 
C) DA antagonists 
D) Cholinergics

Question 5

While taking Selegiline,which of the following food/beverage should be avoided?

Accepted Answer

A) Yogurt 
B) Grapefruit juice 
C) Cottage cheese 
D) Oranges 
A) Yogurt 
B) Grapefruit juice 
C) Cottage cheese 
D) Oranges

Question 6

Which of the following would be used to reduce cholinergic activity?

Accepted Answer

A) Entacapone 
B) Bromocriptine 
C) Ropinirole 
D) Trihexyphenidyl 
A) Entacapone 
B) Bromocriptine 
C) Ropinirole 
D) Trihexyphenidyl

Question 7

Why would the efficacy of levodopa decrease over time?

Accepted Answer

A) Long-term use of levodopa creates a tolerance to the drug,decreasing its efficacy. 
B) Progressive desensitization of DA receptors requires an increased amount of DA to produce therapeutic effects. 
C) The mechanism by which levodopa is metabolized eventually becomes compromised because its constant levels in the brain decrease its efficacy. 
D) Levodopa eventually causes liver damage and is unable to be completely metabolized in the body decreasing its efficacy. 
A) Long-term use of levodopa creates a tolerance to the drug,decreasing its efficacy. 
B) Progressive desensitization of DA receptors requires an increased amount of DA to produce therapeutic effects. 
C) The mechanism by which levodopa is metabolized eventually becomes compromised because its constant levels in the brain decrease its efficacy. 
D) Levodopa eventually causes liver damage and is unable to be completely metabolized in the body decreasing its efficacy.

Question 8

Huntington's disease is primarily treated with drugs that decrease excessive _____ activity.

Accepted Answer

A) cholinergic 
B) AChE 
C) dopaminergic 
D) GABA enzyme 
A) cholinergic 
B) AChE 
C) dopaminergic 
D) GABA enzyme

Question 9

Which of the following would be used to block acetylcholine receptors?

Accepted Answer

A) Trihexyphenidyl 
B) Rasagiline 
C) Tolcapone 
D) Rotigotine 
A) Trihexyphenidyl 
B) Rasagiline 
C) Tolcapone 
D) Rotigotine

Question 10

Which of the following would be used to enhance DA activity?

Accepted Answer

A) Carbidopa 
B) Haloperidol 
C) Tetrabenazine 
D) Trihexyphenidyl 
A) Carbidopa 
B) Haloperidol 
C) Tetrabenazine 
D) Trihexyphenidyl

Question 11

Which of the following would be used to treat Huntington's disease?

Accepted Answer

A) Benztropine 
B) Selegiline 
C) Haloperidol 
D) Pramipexole 
A) Benztropine 
B) Selegiline 
C) Haloperidol 
D) Pramipexole

Exam 8: Treatment of Parkinsons Disease and Huntingtons Disease

Why would Levodopa be administered instead of oral DA to help treat Parkinson's disease?

Which of the following would be used to block DA receptors?

What is thought to be a rare cause of Parkinson's disease in person's under 40 years old?

_____ can be administered to lessen drug-induced extrapyramidal symptoms.

While taking Selegiline,which of the following food/beverage should be avoided?

Which of the following would be used to reduce cholinergic activity?

Why would the efficacy of levodopa decrease over time?

Huntington's disease is primarily treated with drugs that decrease excessive _____ activity.

Which of the following would be used to block acetylcholine receptors?

Which of the following would be used to enhance DA activity?

Which of the following would be used to treat Huntington's disease?

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

Treatment of Anxiety

Treatment of Depression

Treatment of Schizophrenia and Psychoses

Treatment of Seizure Disorders

Treatment of Pain and Migraine Headache

Treatment of Alzheimers Disease

Treatment of Sleep Disorders and Attention-Deficit Hyperactivity Disorder

Neuromuscular Blockade

Treatment of Muscle Spasms

Treatment of Autoimmune Diseases That Affect the Musculoskeletal System

Treatment of Osteoporosis and Pagets Disease of the Bone

Treatment of Hyperuricemia and Gout

Treatment of Glaucoma

Treatment of Disorders of the Ear

Treatment of Ophthalmic and Otic Infections

Treatment of Angina

Treatment of Hypertension

Treatment of Heart Failure

Treatment of Myocardial Infarction and Stroke

Treatment of Arrhythmia

Treatment of Gastroesophageal Reflux Disease, Laryngopharyngeal Reflux, and Peptic Ulcer Disease

Treatment of Irritable Bowel Syndrome, ulcerative Colitis, and Crohns Disease

Treatment of Asthma and Chronic Obstructive Pulmonary Disease

Treatment of Allergies

Treatment of Prostate Disease and Erectile Dysfunction

Treatment of Fluid and Electrolyte Disorders

Treatment of Thyroid Disorders

Treatment of Diabetes Mellitus

Drugs That Affect the Reproductive System

Treatment of Bacterial Infection

Treatment of Viral Infections

Treatment of Cancers

Vaccines, Immunomodulators, and Immunosuppressants

Treatment of Fungal Infections

Treatment of Decubitus Ulcers and Burns

Treatment of Acne

Treatment of Eczema and Psoriasis

Treatment of Lice and Scabies

Filters