Question 1

Why would a long half-life be beneficial yet unfavorable when taking a TCA?

Accepted Answer

A) It would allow for increased chance of elimination,reducing its effects. 
B) The drug would allow for decreased dosing,but side effects would last longer. 
C) A longer half-life increases the chance of the drug being metabolized,decreasing possible side effects. 
D) The drug would allow for decreased dosing but would also decrease its therapeutic effects. 
A) It would allow for increased chance of elimination,reducing its effects. 
B) The drug would allow for decreased dosing,but side effects would last longer. 
C) A longer half-life increases the chance of the drug being metabolized,decreasing possible side effects. 
D) The drug would allow for decreased dosing but would also decrease its therapeutic effects.

Question 2

Serotonin (5-hydroxytryptamine [5-HT])is an inhibitory transmitter.

Accepted Answer

A) True 
 B)False

Question 3

The monoamine neurotransmitters that are depleted in clinical depressions are NE,_____,and dopamine (DA).

Accepted Answer

A) GABA 
B) 5-HT 
C) EPI 
D) glutamate 
A) GABA 
B) 5-HT 
C) EPI 
D) glutamate

Question 4

MATCHING
Match each of the following generic names with its trade name.
-Sinequan

Accepted Answer

A) Tranylcypromine 
B) Imipramine 
C) Citalopram 
D) Doxepin 
E) Escitalopram 
A) Tranylcypromine 
B) Imipramine 
C) Citalopram 
D) Doxepin 
E) Escitalopram

Question 5

Tricyclic antidepressants (TCAs)are used only to treat depression.

Accepted Answer

A) True 
 B)False

Question 6

Which of the following is an example of an MAOI?

Accepted Answer

A) Imipramine 
B) Tranylcypromine 
C) Mirtazapine 
D) Citalopram 
A) Imipramine 
B) Tranylcypromine 
C) Mirtazapine 
D) Citalopram

Question 7

Which of the following is an example of an SSRI?

Accepted Answer

A) Nortriptyline 
B) Phenelzine 
C) Bupropion 
D) Sertraline 
A) Nortriptyline 
B) Phenelzine 
C) Bupropion 
D) Sertraline

Question 8

Why do plasma levels and renal function need to be monitored when taking lithium?

Accepted Answer

A) To make sure sodium levels are increased to allow for resorption of lithium 
B) To ensure lithium is not being reabsorbed through the kidneys,causing lithium toxicity 
C) To make sure sodium is allowing for resorption of lithium to increase lithium levels in the body 
D) To ensure lithium is being reabsorbed through the liver and remaining in the body to produce its effects 
A) To make sure sodium levels are increased to allow for resorption of lithium 
B) To ensure lithium is not being reabsorbed through the kidneys,causing lithium toxicity 
C) To make sure sodium is allowing for resorption of lithium to increase lithium levels in the body 
D) To ensure lithium is being reabsorbed through the liver and remaining in the body to produce its effects

Question 9

Dysthymia symptoms are more severe than those of major depression.

Accepted Answer

A) True 
 B)False

Question 10

Which statement is not true about lithium?

Accepted Answer

A) It has a narrow therapeutic index. 
B) It absorbed in the gastrointestinal (GI)tract. 
C) It has a slow onset of action. 
D) It has a t 1/2 of 24 hours. 
A) It has a narrow therapeutic index. 
B) It absorbed in the gastrointestinal (GI)tract. 
C) It has a slow onset of action. 
D) It has a t 1/2 of 24 hours.

Question 11

Venlafaxine belongs to which class of drugs?

Accepted Answer

A) MAOI 
B) SSRI 
C) Serotonin-noradrenaline reuptake inhibitor (SNRI) 
D) TCA 
A) MAOI 
B) SSRI 
C) Serotonin-noradrenaline reuptake inhibitor (SNRI) 
D) TCA

Exam 6: Treatment of Depression

Why would a long half-life be beneficial yet unfavorable when taking a TCA?

Serotonin (5-hydroxytryptamine [5-HT])is an inhibitory transmitter.

The monoamine neurotransmitters that are depleted in clinical depressions are NE,_____,and dopamine (DA).

MATCHING Match each of the following generic names with its trade name. -Sinequan

Tricyclic antidepressants (TCAs)are used only to treat depression.

Which of the following is an example of an MAOI?

Which of the following is an example of an SSRI?

Why do plasma levels and renal function need to be monitored when taking lithium?

Dysthymia symptoms are more severe than those of major depression.

Which statement is not true about lithium?

Venlafaxine belongs to which class of drugs?

Fundamentals of Pharmacology

Principles of Pharmacology

Pharmacodynamics

Drug Interactions and Medication Errors

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