Question 1

What species are combined to produce carbamoyl phosphate?

Accepted Answer

A)  NH3, PO43-, HCO3- 
B)  NH4+, PO43-, Ac-CoA, releasing CoA-SH 
C)  glycine and inorganic phosphate, releasing CO2 
D)  acetate and NH4+, releasing CO2 
E)  alanine and inorganic phosphate, releasing acetate 
A)  NH3, PO43-, HCO3- 
B)  NH4+, PO43-, Ac-CoA, releasing CoA-SH 
C)  glycine and inorganic phosphate, releasing CO2 
D)  acetate and NH4+, releasing CO2 
E)  alanine and inorganic phosphate, releasing acetate A

Question 2

Which of the following organisms excrete uric acid?

Accepted Answer

A)  birds 
B)  reptiles 
C)  jellyfish 
D)  A and B 
E)  all of the above 
A)  birds 
B)  reptiles 
C)  jellyfish 
D)  A and B 
E)  all of the above D

Question 3

What do birds excrete as nitrogen waste instead of urea?

Accepted Answer

A)  asparagine 
B)  uric acid 
C)  carbamoyl phosphate 
D)  citrulline 
E)  arginine 
A)  asparagine 
B)  uric acid 
C)  carbamoyl phosphate 
D)  citrulline 
E)  arginine B

Question 4

The cofactor ______ is used to transfer C-1 units such as methyl, formyl, and methenyl groups.

Accepted Answer

The answer of The cofactor ______ is used to transfer...

Question 5

Which urea cycle intermediate reacts with carbamoyl phosphate?

Accepted Answer

A)  citrulline 
B)  aspartate 
C)  argininosuccinate 
D)  arginine 
E)  ornithine 
A)  citrulline 
B)  aspartate 
C)  argininosuccinate 
D)  arginine 
E)  ornithine

Question 6

Which of the following amino acids is exclusively ketogenic?

Accepted Answer

A)  Leu 
B)  Val 
C)  Phe 
D)  Arg 
E)  Thr 
A)  Leu 
B)  Val 
C)  Phe 
D)  Arg 
E)  Thr

Question 7

Which of the following contains the correct sequence of reactants for carbamoyl phosphate synthetase?

Accepted Answer

A)  ATP and ammonia, then bicarbonate, then ATP 
B)  ATP and ammonia, then ATP, then bicarbonate 
C)  ATP and bicarbonate, then ammonia, then ATP 
D)  ATP and bicarbonate, then ATP, then ammonia 
E)  ammonia and bicarbonate, then two ATP molecules 
A)  ATP and ammonia, then bicarbonate, then ATP 
B)  ATP and ammonia, then ATP, then bicarbonate 
C)  ATP and bicarbonate, then ammonia, then ATP 
D)  ATP and bicarbonate, then ATP, then ammonia 
E)  ammonia and bicarbonate, then two ATP molecules

Question 8

The enzyme ______ is critical to regulating nitrogen metabolism.

Accepted Answer

glutamine

Question 9

Glutamate undergoes a(n) _____, catalyzed by glutamate dehydrogenase, to yield $\alpha$-ketoglutarate, NADH, and _____.

Accepted Answer

A)  reductive deamination; water 
B)  oxidative deamination; ammonia 
C)  reductive amination; water 
D)  oxidative amination; ammonia 
E)  none of the above 
A)  reductive deamination; water 
B)  oxidative deamination; ammonia 
C)  reductive amination; water 
D)  oxidative amination; ammonia 
E)  none of the above

Question 10

_____ are involved in the nonselective degradation of milk proteins in neonates.

Accepted Answer

The answer of _____ are involved in the nonselective degradation...

Question 11

In high levels, ammonia is toxic to _____ cells.

Accepted Answer

A)  kidney 
B)  cardiac 
C)  liver 
D)  nerve 
E)  intestinal 
A)  kidney 
B)  cardiac 
C)  liver 
D)  nerve 
E)  intestinal

Question 12

In the mechanism of carbamoyl phosphate synthetase, what undergoes nucleophilic attack by ammonia?

Accepted Answer

A)  the carbonyl group of carboxyphosphate 
B)  the terminal phosphate of ATP 
C)  the middle phosphate of ATP 
D)  the carbonyl group of carbamate 
E)  the phosphate of carboxyphosphate 
A)  the carbonyl group of carboxyphosphate 
B)  the terminal phosphate of ATP 
C)  the middle phosphate of ATP 
D)  the carbonyl group of carbamate 
E)  the phosphate of carboxyphosphate

Question 13

What enzyme associated with the urea cycle enzyme is activated by N-acetylglutamate?

Accepted Answer

A)  carbamoyl phosphate synthetase 
B)  glutamate dehydrogenase 
C)  argininosuccinate synthetase 
D)  arginase 
E)  ornithine transcarbamoylase 
A)  carbamoyl phosphate synthetase 
B)  glutamate dehydrogenase 
C)  argininosuccinate synthetase 
D)  arginase 
E)  ornithine transcarbamoylase

Question 14

Degradation to pyruvate makes an amino acid _____; degradation to acetoacetate makes an amino acid _____.

Accepted Answer

A)  glucogenic; glucogenic 
B)  glucogenic; glucogenic and ketogenic 
C)  glucogenic; ketogenic 
D)  ketogenic; glucogenic 
E)  ketogenic; ketogenic 
A)  glucogenic; glucogenic 
B)  glucogenic; glucogenic and ketogenic 
C)  glucogenic; ketogenic 
D)  ketogenic; glucogenic 
E)  ketogenic; ketogenic

Question 15

What type of reaction is used to deaminate amino acids, resulting in a new amino acid and a new $\alpha$-keto acid?

Accepted Answer

A)  ATP-dependent ligation 
B)  transamination 
C)  oxidation 
D)  condensation 
E)  reduction 
A)  ATP-dependent ligation 
B)  transamination 
C)  oxidation 
D)  condensation 
E)  reduction

Question 16

The amino acid _____ has been thought to act as a transfer system for NH3, safely allowing the toxic molecule to be transported from the liver to the kidneys.

Accepted Answer

Exam 11: Amine Metabolism

What species are combined to produce carbamoyl phosphate?

Which of the following organisms excrete uric acid?

What do birds excrete as nitrogen waste instead of urea?

The cofactor ______ is used to transfer C-1 units such as methyl, formyl, and methenyl groups.

Which urea cycle intermediate reacts with carbamoyl phosphate?

Which of the following amino acids is exclusively ketogenic?

Which of the following contains the correct sequence of reactants for carbamoyl phosphate synthetase?

The enzyme ______ is critical to regulating nitrogen metabolism.

Glutamate undergoes a(n) _____, catalyzed by glutamate dehydrogenase, to yield α\alphaα -ketoglutarate, NADH, and _____.

_____ are involved in the nonselective degradation of milk proteins in neonates.

In high levels, ammonia is toxic to _____ cells.

In the mechanism of carbamoyl phosphate synthetase, what undergoes nucleophilic attack by ammonia?

What enzyme associated with the urea cycle enzyme is activated by N-acetylglutamate?

Degradation to pyruvate makes an amino acid _____; degradation to acetoacetate makes an amino acid _____.

What type of reaction is used to deaminate amino acids, resulting in a new amino acid and a new α\alphaα -keto acid?

The amino acid _____ has been thought to act as a transfer system for NH3, safely allowing the toxic molecule to be transported from the liver to the kidneys.

The Chemical Foundations of Biochemistry

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Rna Synthesis

Protein

Control of Gene

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Bioinformatics and Omics

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

Glutamate undergoes a(n) _, catalyzed by glutamate dehydrogenase, to yield $\alpha$ -ketoglutarate, NADH, and _.

Degradation to pyruvate makes an amino acid _; degradation to acetoacetate makes an amino acid _.

What type of reaction is used to deaminate amino acids, resulting in a new amino acid and a new $\alpha$ -keto acid?

The amino acid _____ has been thought to act as a transfer system for NH₃, safely allowing the toxic molecule to be transported from the liver to the kidneys.