Question 1

What is the conjugate acid of H2PO4-?

Accepted Answer

A)  HPO42- 
B)  H2PO4 
C)  H3PO4 
D)  PO43- 
E)  none of the above 
A)  HPO42- 
B)  H2PO4 
C)  H3PO4 
D)  PO43- 
E)  none of the above C

Question 2

Of the following amino acids, which contains an alcohol?

Accepted Answer

A)  A 
B)  B 
C)  C 
D)  D 
E)  all of the above 
A)  A 
B)  B 
C)  C 
D)  D 
E)  all of the above A

Question 3

What is the [H+] of an aqueous solution with a pH of 6.2?

Accepted Answer

A)  6.2 × 10-6 
B)  1.6 × 10-8 
C)  6.3 × 10-7 
D)  3. 3 × 10-5 
E)  none of the above 
A)  6.2 × 10-6 
B)  1.6 × 10-8 
C)  6.3 × 10-7 
D)  3. 3 × 10-5 
E)  none of the above C

Question 4

In an aqueous solution, if the [OH-] is 3.0 × 10-5 M, what is the [H+]?

Accepted Answer

A)  7.0 × 10-9 
B)  7.0 × 10-2 
C)  3.3 × 10-3 
D)  3.3 × 10-10 
E)  none of the above 
A)  7.0 × 10-9 
B)  7.0 × 10-2 
C)  3.3 × 10-3 
D)  3.3 × 10-10 
E)  none of the above

Question 5

If a reaction at 37$\degree$C has a $\Delta$H of 23 kJ/mol and a $\Delta$S of 337 J/K.mol, what is the $\Delta$G for the reaction?

Accepted Answer

A)  65 kJ/mol 
B)  -42 kJ/mol 
C)  18 kJ/mol 
D)  -19 kJ/mol 
E)  none of the above 
A)  65 kJ/mol 
B)  -42 kJ/mol 
C)  18 kJ/mol 
D)  -19 kJ/mol 
E)  none of the above

Question 6

What functional groups are present in the following molecule?

Accepted Answer

A)  amine and carboxylic acid 
B)  amine, ketone, and carboxylic acid 
C)  amine, amide, and carboxylic acid 
D)  alcohol, amine, amide, and carboxylic acid 
E)  none of the above are correct 
A)  amine and carboxylic acid 
B)  amine, ketone, and carboxylic acid 
C)  amine, amide, and carboxylic acid 
D)  alcohol, amine, amide, and carboxylic acid 
E)  none of the above are correct

Question 7

Urea is a water-soluble product of nitrogen metabolism. How many hydrogen bonds can one urea molecule donate to surrounding water molecules?

Accepted Answer

A)  2 
B)  3 
C)  4 
D)  5 
E)  6 
A)  2 
B)  3 
C)  4 
D)  5 
E)  6

Question 8

Metabolic acidosis often causes increased respiratory rates. What portion of the bloodstream buffer is lost through increased respiration?

Accepted Answer

A)  H+ 
B)  HCO3- 
C)  H2CO3 
D)  CO2 
E)  H2O 
A)  H+ 
B)  HCO3- 
C)  H2CO3 
D)  CO2 
E)  H2O

Question 9

Which of the following is a physical property of water that results from hydrogen bonding?

Accepted Answer

A)  a high boiling point relative to molecular weight 
B)  a solid state that is less dense than the liquid state 
C)  high surface tension 
D)  the ability to solubilize polar molecules 
E)  all of the above 
A)  a high boiling point relative to molecular weight 
B)  a solid state that is less dense than the liquid state 
C)  high surface tension 
D)  the ability to solubilize polar molecules 
E)  all of the above

Question 10

Keq can be determined from the change in standard free energy using the equation ______.

Accepted Answer

A)  Keq = e-$\Delta$G°/RT 
B)  Keq = ln e-$\Delta$G°/T$\Delta$S 
C)  Keq = e-$\Delta$H/RT 
D)  Keq = e-$\Delta$G°/T$\Delta$S 
E)  Keq = log e-$\Delta$G°/RT 
A)  Keq = e-$\Delta$G°/RT 
B)  Keq = ln e-$\Delta$G°/T$\Delta$S 
C)  Keq = e-$\Delta$H/RT 
D)  Keq = e-$\Delta$G°/T$\Delta$S 
E)  Keq = log e-$\Delta$G°/RT

Question 11

Consider the isomerization reaction R $\rightleftarrows$P, in which R is converted to P. The $\Delta$G°' for this reaction is -10. kJ/mol. Calculate the [P]/[R] at equilibrium at 25°C.

Accepted Answer

At equilibrium [P]/[R] = K_eq

Question 12

What would be the resulting pH if one ml of 1.0 M NaOH was added to one liter of pure water (assume pH 7.0)?

Accepted Answer

A)  1 
B)  3 
C)  7.3 
D)  11 
E)  13 
A)  1 
B)  3 
C)  7.3 
D)  11 
E)  13

Question 13

-In a water molecule, hydrogens are partially _____; oxygens are partially _____.

Accepted Answer

A)  negative; negative 
B)  negative; positive 
C)  positive; positive 
D)  positive; negative 
E)  none of the above 
A)  negative; negative 
B)  negative; positive 
C)  positive; positive 
D)  positive; negative 
E)  none of the above

Question 14

Which of the following shows the buffer that is found in the bloodstream?

Accepted Answer

A)  H3PO4 $ \rightleftharpoons $H2PO42- + H+ 
B)  H2PO4- $ \rightleftharpoons $ HPO42- + H+ 
C)  HPO42- $ \rightleftharpoons $ PO43- + H+ 
D)  H2CO3 $ \rightleftharpoons $ HCO3- + H+ 
E)  HCO3-  $ \rightleftharpoons $ CO32- + H+ 
A)  H3PO4 $ \rightleftharpoons $H2PO42- + H+ 
B)  H2PO4- $ \rightleftharpoons $ HPO42- + H+ 
C)  HPO42- $ \rightleftharpoons $ PO43- + H+ 
D)  H2CO3 $ \rightleftharpoons $ HCO3- + H+ 
E)  HCO3-  $ \rightleftharpoons $ CO32- + H+

Question 15

-Which arrow points at an amide bond?

Accepted Answer

A)  A 
B)  B 
C)  C 
D)  D 
E)  E 
A)  A 
B)  B 
C)  C 
D)  D 
E)  E

Question 16

-Which arrow points at a phosphoester bond?

Accepted Answer

A)  A 
B)  B 
C)  C 
D)  D 
E)  E 
A)  A 
B)  B 
C)  C 
D)  D 
E)  E

Question 17

If a phosphate buffer (pK = 6.82) was formulated such that its pH was 7.3, it would be best suited to buffer against _____. If instead, it was formulated such that its pH was 6.3, it would be best suited to buffer against _____.

Accepted Answer

A)  acid; base 
B)  acid; acid 
C)  base; acid 
D)  base; base 
E)  a buffer with a pH that far from the pK would not be an effective buffer 
A)  acid; base 
B)  acid; acid 
C)  base; acid 
D)  base; base 
E)  a buffer with a pH that far from the pK would not be an effective buffer

Question 18

Due to the formation of hydrogen bonds, _____ is highly soluble in water.

Accepted Answer

A)  carbon dioxide 
B)  sodium chloride 
C)  methanol 
D)  octane 
E)  cholesterol 
A)  carbon dioxide 
B)  sodium chloride 
C)  methanol 
D)  octane 
E)  cholesterol

Question 19

Consider a reaction in which $\Delta$H = -20. kJ/mol and $\Delta$S = 10. J/mol · K.

Accepted Answer

a. @#LAT-DLM&G = @#LAT-DLM&H - @#LAT-DLM&S @#LAT-DLM&@#LAT-DLM&G = -20,000 J/mol

Question 20

Which of the following would be the strongest acid?

Accepted Answer

A)  formic acid, pK = 3.75 
B)  succinic acid, a diprotic acid with pK = 4.21 and 5.64 
C)  acetic acid, pK = 4.76 
D)  ammonium ion, pK = 9.25 
E)  cannot be determined from the given information 
A)  formic acid, pK = 3.75 
B)  succinic acid, a diprotic acid with pK = 4.21 and 5.64 
C)  acetic acid, pK = 4.76 
D)  ammonium ion, pK = 9.25 
E)  cannot be determined from the given information

Exam 1: The Chemical Foundations of Biochemistry

What is the conjugate acid of H2PO4-?

Of the following amino acids, which contains an alcohol?

What is the [H+] of an aqueous solution with a pH of 6.2?

In an aqueous solution, if the [OH-] is 3.0 × 10-5 M, what is the [H+]?

If a reaction at 37 °\degree° C has a Δ\DeltaΔ H of 23 kJ/mol and a Δ\DeltaΔ S of 337 J/K.mol, what is the Δ\DeltaΔ G for the reaction?

What functional groups are present in the following molecule?

Urea is a water-soluble product of nitrogen metabolism. How many hydrogen bonds can one urea molecule donate to surrounding water molecules?

Metabolic acidosis often causes increased respiratory rates. What portion of the bloodstream buffer is lost through increased respiration?

Which of the following is a physical property of water that results from hydrogen bonding?

Keq can be determined from the change in standard free energy using the equation ______.

Consider the isomerization reaction R ⇄\rightleftarrows⇄ P, in which R is converted to P. The Δ\DeltaΔ G°' for this reaction is -10. kJ/mol. Calculate the [P]/[R] at equilibrium at 25°C.

What would be the resulting pH if one ml of 1.0 M NaOH was added to one liter of pure water (assume pH 7.0)?

-In a water molecule, hydrogens are partially _____; oxygens are partially _____.

Which of the following shows the buffer that is found in the bloodstream?

-Which arrow points at an amide bond?

-Which arrow points at a phosphoester bond?

If a phosphate buffer (pK = 6.82) was formulated such that its pH was 7.3, it would be best suited to buffer against _____. If instead, it was formulated such that its pH was 6.3, it would be best suited to buffer against _____.

Due to the formation of hydrogen bonds, _____ is highly soluble in water.

Consider a reaction in which Δ\DeltaΔ H = -20. kJ/mol and Δ\DeltaΔ S = 10. J/mol · K.

Which of the following would be the strongest acid?

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Amine Metabolism

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Rna Synthesis

Protein

Control of Gene

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Bioinformatics and Omics

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

What is the conjugate acid of H₂PO₄^-?

What is the [H⁺] of an aqueous solution with a pH of 6.2?

In an aqueous solution, if the [OH^-] is 3.0 × 10^-5 M, what is the [H⁺]?

If a reaction at 37 $\degree$ C has a $\Delta$ H of 23 kJ/mol and a $\Delta$ S of 337 J/K.mol, what is the $\Delta$ G for the reaction?

K_eq can be determined from the change in standard free energy using the equation ______.

Consider the isomerization reaction R $\rightleftarrows$ P, in which R is converted to P. The $\Delta$ G°' for this reaction is -10. kJ/mol. Calculate the [P]/[R] at equilibrium at 25°C.

-In a water molecule, hydrogens are partially _; oxygens are partially _.

If a phosphate buffer (pK = 6.82) was formulated such that its pH was 7.3, it would be best suited to buffer against _. If instead, it was formulated such that its pH was 6.3, it would be best suited to buffer against _.

Consider a reaction in which $\Delta$ H = -20. kJ/mol and $\Delta$ S = 10. J/mol · K.