Question 1

Cells that are able to differentiate into a limited number of cell types are

Accepted Answer

A)  totipotent 
B)  pluripotent 
C)  terminally potent 
D)  chromosomally active 
E)  inducible 
A)  totipotent 
B)  pluripotent 
C)  terminally potent 
D)  chromosomally active 
E)  inducible A

Question 2

What sugar is metabolized by the enzymes under the control of the lac operon?

Accepted Answer

A)  sucrose 
B)  mannose 
C)  galactose 
D)  lactose 
E)  maltose 
A)  sucrose 
B)  mannose 
C)  galactose 
D)  lactose 
E)  maltose D

Question 3

The mechanism of action of drugs such as thiazolidine diones that treat diabetes, and some cholesterol lower drugs is binding and inactivation of transcripton factors such as

Accepted Answer

A)  PPARs 
B)  HOX gene proteins 
C)  CREBs 
D)  SREBPs 
E)  C/EBPs 
A)  PPARs 
B)  HOX gene proteins 
C)  CREBs 
D)  SREBPs 
E)  C/EBPs A

Question 4

Eukaryotic posttranscriptional control of gene expression does NOT include

Accepted Answer

A)  differential degradation of mRNA. 
B)  attenuation. 
C)  interference by RNA sequences. 
D)  splicing. 
E)  nuclear transport 
A)  differential degradation of mRNA. 
B)  attenuation. 
C)  interference by RNA sequences. 
D)  splicing. 
E)  nuclear transport

Question 5

Humans have about the same number of genes as

Accepted Answer

A)  E. coli 
B)  yeast 
C)  flatworm 
D)  colonial amoeba 
E)  none of the above 
A)  E. coli 
B)  yeast 
C)  flatworm 
D)  colonial amoeba 
E)  none of the above

Question 6

cAMP, highly conserved throughout evolution,

Accepted Answer

A)  indicates cellular energy state 
B)  is involved in eukaryotic cell signaling pathways 
C)  activate energy mobilization pathways 
D)  is high in prokaryotes when glucose is absent 
E)  all of the above 
A)  indicates cellular energy state 
B)  is involved in eukaryotic cell signaling pathways 
C)  activate energy mobilization pathways 
D)  is high in prokaryotes when glucose is absent 
E)  all of the above

Question 7

A gene that undergoes positive regulation is called ___.

Accepted Answer

The answer of A gene that undergoes positive regulation is...

Question 8

To induce expression of the lac operon, _______ can be added to the cell medium.

Accepted Answer

lactose or

Question 9

The ______ proteins can undergo posttranslational modification by acetylation, 
phosphorylation, methylation, and ubiquitination.

Accepted Answer

The answer of The ______ proteins can undergo posttranslational modification...

Question 10

PPAR transcription factors

Accepted Answer

A)  are mostly important to nervous system development 
B)  are of the leucine zipper type 
C)  in their inactive state can reside in the cytosol or nucleus 
D)  commonly forms homodimers 
E)  recognizes the DNA sequence 5' - TAAT - 3' 
A)  are mostly important to nervous system development 
B)  are of the leucine zipper type 
C)  in their inactive state can reside in the cytosol or nucleus 
D)  commonly forms homodimers 
E)  recognizes the DNA sequence 5' - TAAT - 3'

Question 11

Expression of specific genes in particular cells are regulated through the interaction of the genome with proteins. Both the regulatory regions of the genome and the primary structure of the regulatory proteins is conserved evolutionarily over many species.

Accepted Answer

A)  Both sentences are true 
B)  Both sentences are false 
C)  The first sentence is true and the second sentence is false 
D)  The first sentence is false and the second sentence is true 
A)  Both sentences are true 
B)  Both sentences are false 
C)  The first sentence is true and the second sentence is false 
D)  The first sentence is false and the second sentence is true

Question 12

G-protein coupled receptor signaling pathways are important to

Accepted Answer

A)  PPARs 
B)  SREBPs 
C)  CREBs 
D)  HOX gene proteins 
E)  C/EBPs 
A)  PPARs 
B)  SREBPs 
C)  CREBs 
D)  HOX gene proteins 
E)  C/EBPs

Question 13

What is common among the following: arg, his, lys?

Accepted Answer

A)  all are basic amino acids 
B)  histones are enriched in these amino acids 
C)  all can interact with DNA through ionic and other weak interactions 
D)  both (
A)  and (
B)  are correct 
E)  all of the above 
A)  all are basic amino acids 
B)  histones are enriched in these amino acids 
C)  all can interact with DNA through ionic and other weak interactions 
D)  both (
A)  and (
B)  are correct 
E)  all of the above

Question 14

What does allolactose bind?

Accepted Answer

A)  lac operon 
B)  lac repressor 
C)  operator 
D)  promoter 
E)  all of the above 
A)  lac operon 
B)  lac repressor 
C)  operator 
D)  promoter 
E)  all of the above

Question 15

Which is NOT true of HOX genes?

Accepted Answer

A)  They give rise to transcription factors containing a homeodomain 
B)  They were identified in Drosophila, and found to be highly conserved 
C)  Their binding motif is a zinc finger 
D)  Small mutations in HOX gene promoters have been found to significantly affect basic phenotype 
E)  Their position in the genome regulates their expression 
A)  They give rise to transcription factors containing a homeodomain 
B)  They were identified in Drosophila, and found to be highly conserved 
C)  Their binding motif is a zinc finger 
D)  Small mutations in HOX gene promoters have been found to significantly affect basic phenotype 
E)  Their position in the genome regulates their expression

Question 16

Which is NOT true of the helix-turn-helix motif?

Accepted Answer

A)  It contains a complexed divalent cation 
B)  It is similar in structure to helix-loop-helix motif 
C)  It is one of the most common regulatory protein motifs 
D)  Its helices interact with DNA 
E)  It binds DNA through hydrogen bonding 
A)  It contains a complexed divalent cation 
B)  It is similar in structure to helix-loop-helix motif 
C)  It is one of the most common regulatory protein motifs 
D)  Its helices interact with DNA 
E)  It binds DNA through hydrogen bonding

Question 17

Tight control of tryptophan synthesis is advantageous evolutionarily in prokaryotes because

Accepted Answer

A)  trp synthesis requires several enzymes 
B)  trp synthesis requires several different genes 
C)  trp serves as a precursor to prokaryotic coenzymes 
D)  trp is not always available to the organism 
E)  all of the above 
A)  trp synthesis requires several enzymes 
B)  trp synthesis requires several different genes 
C)  trp serves as a precursor to prokaryotic coenzymes 
D)  trp is not always available to the organism 
E)  all of the above

Question 18

Post-translational histone modifications commonly

Accepted Answer

A)  occur on histone tails 
B)  involve lys and arg residues 
C)  modulate histone/DNA interactions 
D)  both (
A)  and (
B)  
E)  all of the above 
A)  occur on histone tails 
B)  involve lys and arg residues 
C)  modulate histone/DNA interactions 
D)  both (
A)  and (
B)  
E)  all of the above

Question 19

RNAi is useful to experimental and therapeutic biochemistry because

Accepted Answer

A)  it uses the cell's own machinery 
B)  it can affect many different genes 
C)  it can specifically silence a particular gene or a family of genes 
D)  it is relatively inexpensive and adaptable to varied experimental conditions 
E)  all of the above 
A)  it uses the cell's own machinery 
B)  it can affect many different genes 
C)  it can specifically silence a particular gene or a family of genes 
D)  it is relatively inexpensive and adaptable to varied experimental conditions 
E)  all of the above

Question 20

Genes that are not often transcribed in the presence of a specific metabolite are _____ and are called ____.

Accepted Answer

A)  upregulated; repressible 
B)  upregulated; trans elements 
C)  downregulated; cis elements 
D)  downregulated; repressible 
E)  downregulated; inducible 
A)  upregulated; repressible 
B)  upregulated; trans elements 
C)  downregulated; cis elements 
D)  downregulated; repressible 
E)  downregulated; inducible

Exam 17: Control of Gene

Cells that are able to differentiate into a limited number of cell types are

What sugar is metabolized by the enzymes under the control of the lac operon?

The mechanism of action of drugs such as thiazolidine diones that treat diabetes, and some cholesterol lower drugs is binding and inactivation of transcripton factors such as

Eukaryotic posttranscriptional control of gene expression does NOT include

Humans have about the same number of genes as

cAMP, highly conserved throughout evolution,

A gene that undergoes positive regulation is called ___.

To induce expression of the lac operon, _______ can be added to the cell medium.

The ______ proteins can undergo posttranslational modification by acetylation, phosphorylation, methylation, and ubiquitination.

PPAR transcription factors

Expression of specific genes in particular cells are regulated through the interaction of the genome with proteins. Both the regulatory regions of the genome and the primary structure of the regulatory proteins is conserved evolutionarily over many species.

G-protein coupled receptor signaling pathways are important to

What is common among the following: arg, his, lys?

What does allolactose bind?

Which is NOT true of HOX genes?

Which is NOT true of the helix-turn-helix motif?

Tight control of tryptophan synthesis is advantageous evolutionarily in prokaryotes because

Post-translational histone modifications commonly

RNAi is useful to experimental and therapeutic biochemistry because

Genes that are not often transcribed in the presence of a specific metabolite are _____ and are called ____.

The Chemical Foundations of Biochemistry

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Amine Metabolism

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Rna Synthesis

Protein

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Bioinformatics and Omics

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

Genes that are not often transcribed in the presence of a specific metabolite are _ and are called .