Question 1

Eukaryotic rRNA genes are transcribed and processed in the ______.

Accepted Answer

The answer of Eukaryotic rRNA genes are transcribed and processed...

Question 2

What is the purpose of the poly(A) tail on eukaryotic mRNA?

Accepted Answer

A)  binds to short poly(U) molecules forming duplex RNA that resists degradation 
B)  forms a stem loop to aid in transport to the cytosol 
C)  aids in transport to the lysosome for degradation once the ribosome is finished with it 
D)  binds to the poly(
A)  binding protein to prevent exonuclease activity 
E)  none of the above 
A)  binds to short poly(U) molecules forming duplex RNA that resists degradation 
B)  forms a stem loop to aid in transport to the cytosol 
C)  aids in transport to the lysosome for degradation once the ribosome is finished with it 
D)  binds to the poly(
A)  binding protein to prevent exonuclease activity 
E)  none of the above

Question 3

Coactivators, corepressors and some transcription factors can bind up to ___ base pairs from the transcriptional start site.

Accepted Answer

A)  25 
B)  60 
C)  100 
D)  500 
E)  1000 
A)  25 
B)  60 
C)  100 
D)  500 
E)  1000

Question 4

Which transcription factor is required to aid RNA polymerase in the removal of an incorrect nucleotide incorporated into the growing RNA?

Accepted Answer

A)  TFIIP 
B)  TFIIS 
C)  TFIIT 
D)  TFIIX 
E)  TFIIZ 
A)  TFIIP 
B)  TFIIS 
C)  TFIIT 
D)  TFIIX 
E)  TFIIZ

Question 5

Which class of RNA is transported through several mechanisms, requiring varied protein adaptors?

Accepted Answer

A)  tRNA 
B)  rRNA 
C)  mRNA 
D)  miRNA 
E)  snRNA 
A)  tRNA 
B)  rRNA 
C)  mRNA 
D)  miRNA 
E)  snRNA

Question 6

Which of the following eukaryotic RNA polymerase is correctly paired with the type of RNA that it produces?

Accepted Answer

A)  RNA polymerase III: tRNA 
B)  RNA polymerase I: rRNA 
C)  RNA polymerase II: mRNA from protein-coding genes 
D)  RNA polymerase III: small RNAs such as miRNA and snRNA 
E)  all of the above 
A)  RNA polymerase III: tRNA 
B)  RNA polymerase I: rRNA 
C)  RNA polymerase II: mRNA from protein-coding genes 
D)  RNA polymerase III: small RNAs such as miRNA and snRNA 
E)  all of the above

Question 7

What are the two metal ions found in the active site of RNA polymerase?

Accepted Answer

A)  two Ca2+ 
B)  a Ca2+ and a Zn2+ 
C)  two Zn2+ 
D)  a Zn2+ and a Mg2+ 
E)  two Mg2+ 
A)  two Ca2+ 
B)  a Ca2+ and a Zn2+ 
C)  two Zn2+ 
D)  a Zn2+ and a Mg2+ 
E)  two Mg2+

Question 8

An AT-rich region found in eukaryotic promoters is called the ______ box.

Accepted Answer

The answer of An AT-rich region found in eukaryotic promoters...

Question 9

During termination, Rho acts as a _____.

Accepted Answer

A)  polymerase 
B)  ligase 
C)  NTP hydrolase 
D)  single-strand binding protein 
E)  helicase 
A)  polymerase 
B)  ligase 
C)  NTP hydrolase 
D)  single-strand binding protein 
E)  helicase

Question 10

TFIIH is a transcription factor that is responsible for forming the transcription bubble. For this reason, TFIIH is best described as a _____.

Accepted Answer

A)  gyrase 
B)  ligase 
C)  helicase 
D)  endonuclease 
E)  single-strand binding protein 
A)  gyrase 
B)  ligase 
C)  helicase 
D)  endonuclease 
E)  single-strand binding protein

Question 11

How do the NTPs enter RNA polymerase?

Accepted Answer

A)  base-paired with the incoming (downstream) DNA 
B)  with the incoming DNA but not base-paired with it 
C)  from the exit site, as the DNA leaves the enzymes, the NTPs move in the opposite
Direction 
D)  through a funnel-like channel sized just for NTPs 
E)  there is no specific way, any of the above routes are used 
A)  base-paired with the incoming (downstream) DNA 
B)  with the incoming DNA but not base-paired with it 
C)  from the exit site, as the DNA leaves the enzymes, the NTPs move in the opposite
Direction 
D)  through a funnel-like channel sized just for NTPs 
E)  there is no specific way, any of the above routes are used

Question 12

The drawing below is needed to answer the following two questions  
-This molecule is

Accepted Answer

A)  pseudouridine 
B)  uridine 
C)  5-methyl uridine 
D)  inosine 
E)  carboxymethylaminomethyl-2-thiouridine 
A)  pseudouridine 
B)  uridine 
C)  5-methyl uridine 
D)  inosine 
E)  carboxymethylaminomethyl-2-thiouridine

Question 13

RNA polymerases have an error rate of about 1 in ____ bases incorporated, which is much ___ than DNA polymerases.

Accepted Answer

A)  100,000; higher 
B)  100,000; lower 
C)  108; higher 
D)  10-8; higher 
E)  none of the above 
A)  100,000; higher 
B)  100,000; lower 
C)  108; higher 
D)  10-8; higher 
E)  none of the above

Question 14

NPC nucleoproteins are conserved between
I. membrane-associated pore-forming structures
II. clathrin proteins
III. tubulin proteins
IV. adaptin proteins

Accepted Answer

A)  I only 
B)  II and IV 
C)  III only 
D)  I, II and III 
E)  I, II and IV 
A)  I only 
B)  II and IV 
C)  III only 
D)  I, II and III 
E)  I, II and IV

Question 15

What is the approximate size of the DNA-RNA hybrid present inside the RNA polymerase?

Accepted Answer

A)  3 base pairs 
B)  6 base pairs 
C)  9 base pairs 
D)  12 base pairs 
E)  15 base pairs 
A)  3 base pairs 
B)  6 base pairs 
C)  9 base pairs 
D)  12 base pairs 
E)  15 base pairs

Question 16

Which of the following is the major factor in determining how quickly an mRNA is degraded?

Accepted Answer

A)  overall length of the mRNA 
B)  degree of intron removal 
C)  how quickly the cap is removed 
D)  length of poly(
A)  tail 
E)  all of the above play a role 
A)  overall length of the mRNA 
B)  degree of intron removal 
C)  how quickly the cap is removed 
D)  length of poly(
A)  tail 
E)  all of the above play a role

Question 17

Termination of some bacterial transcription requires the ______ factor.

Accepted Answer

The answer of Termination of some bacterial transcription requires the...

Question 18

Genomic DNA that encodes proteins undergoes the process of _____ to produce _____.

Accepted Answer

A)  transcription; mRNA 
B)  transcription; tRNA 
C)  translation; rRNA 
D)  translation; proteins 
E)  transcription; proteins 
A)  transcription; mRNA 
B)  transcription; tRNA 
C)  translation; rRNA 
D)  translation; proteins 
E)  transcription; proteins

Question 19

Reactions occurring within the spliceosome seem to be similar in various ways to

Accepted Answer

A)  self-splicing class II introns 
B)  restriction endonucleases 
C)  DNA polymerase III proofreading 
D)  base excision repair 
E)  Both (
A)  and (
B)  
A)  self-splicing class II introns 
B)  restriction endonucleases 
C)  DNA polymerase III proofreading 
D)  base excision repair 
E)  Both (
A)  and (
B)

Question 20

Which is NOT allowed through the nuclear pore complex (NPC)?

Accepted Answer

A)  DNA 
B)  mRNA 
C)  tRNA 
D)  rRNA 
E)  deoxynucleotides 
A)  DNA 
B)  mRNA 
C)  tRNA 
D)  rRNA 
E)  deoxynucleotides

Exam 15: Rna Synthesis

Eukaryotic rRNA genes are transcribed and processed in the ______.

What is the purpose of the poly(A) tail on eukaryotic mRNA?

Coactivators, corepressors and some transcription factors can bind up to ___ base pairs from the transcriptional start site.

Which transcription factor is required to aid RNA polymerase in the removal of an incorrect nucleotide incorporated into the growing RNA?

Which class of RNA is transported through several mechanisms, requiring varied protein adaptors?

Which of the following eukaryotic RNA polymerase is correctly paired with the type of RNA that it produces?

What are the two metal ions found in the active site of RNA polymerase?

An AT-rich region found in eukaryotic promoters is called the ______ box.

During termination, Rho acts as a _____.

TFIIH is a transcription factor that is responsible for forming the transcription bubble. For this reason, TFIIH is best described as a _____.

How do the NTPs enter RNA polymerase?

The drawing below is needed to answer the following two questions -This molecule is

RNA polymerases have an error rate of about 1 in ____ bases incorporated, which is much ___ than DNA polymerases.

NPC nucleoproteins are conserved between I. membrane-associated pore-forming structures II. clathrin proteins III. tubulin proteins IV. adaptin proteins

What is the approximate size of the DNA-RNA hybrid present inside the RNA polymerase?

Which of the following is the major factor in determining how quickly an mRNA is degraded?

Termination of some bacterial transcription requires the ______ factor.

Genomic DNA that encodes proteins undergoes the process of _____ to produce _____.

Reactions occurring within the spliceosome seem to be similar in various ways to

Which is NOT allowed through the nuclear pore complex (NPC)?

The Chemical Foundations of Biochemistry

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Amine Metabolism

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Protein

Control of Gene

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Bioinformatics and Omics

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

RNA polymerases have an error rate of about 1 in __ bases incorporated, which is much _ than DNA polymerases.

Genomic DNA that encodes proteins undergoes the process of _ to produce _.