Question 1

Within the ribosome during translation, the growing polypeptide chain is always attached to

Accepted Answer

A)  tRNAmet 
B)  the tRNA held in the E site after translocation 
C)  the tRNA held in the E site before translocation 
D)  the tRNA held in the P site after translocation 
E)  the tRNA held in the A site after translocation 
A)  tRNAmet 
B)  the tRNA held in the E site after translocation 
C)  the tRNA held in the E site before translocation 
D)  the tRNA held in the P site after translocation 
E)  the tRNA held in the A site after translocation

Question 2

Given the following anticodon, which mRNA codon would pair with it?
5'-IGC-3'

Accepted Answer

A)  '-UCA-3' 
B)  5'-UCG-3' 
C)  5'-ACU-3' 
D)  5'-GUA-3' 
E)  5'-GCU-3' 
A)  '-UCA-3' 
B)  5'-UCG-3' 
C)  5'-ACU-3' 
D)  5'-GUA-3' 
E)  5'-GCU-3'

Question 3

In the ribosome, interactions among the varied RNA molecules include

Accepted Answer

A)  mRNA and rRNA 
B)  tRNA and mRNA 
C)  tRNA and rRNA 
D)  all of the above 
E)  none of the above 
A)  mRNA and rRNA 
B)  tRNA and mRNA 
C)  tRNA and rRNA 
D)  all of the above 
E)  none of the above

Question 4

Which protein(s) important to translation can be considered guanine nucleotide exchange factors?
I. eIF2
II. eIF3
III. EF-G
IV. EF-Tu

Accepted Answer

A)  I and II 
B)  III and IV 
C)  I, III and IV 
D)  II and III 
E)  IV only 
A)  I and II 
B)  III and IV 
C)  I, III and IV 
D)  II and III 
E)  IV only

Question 5

Approximately what fraction of the mass of a ribosome is due to protein?

Accepted Answer

A)  1/2 
B)  1/3 
C)  1/4 
D)  1/5 
E)  1/6 
A)  1/2 
B)  1/3 
C)  1/4 
D)  1/5 
E)  1/6

Question 6

How is the initiation codon found in eukaryotic translation?

Accepted Answer

A)  a sequence similar to the Shine-Dalgarno sequence is located 
B)  the 5'cap binds just beyond the P site of the ribosome 
C)  the fMet-tRNA is able to locate the initiation codon before binding to the ribosome 
D)  when the mRNA circularizes, the poly(
A)  tail enables location of the initiation codon 
E)  the first AUG codon is found when the 40S subunit scans the mRNA from the 5' end 
A)  a sequence similar to the Shine-Dalgarno sequence is located 
B)  the 5'cap binds just beyond the P site of the ribosome 
C)  the fMet-tRNA is able to locate the initiation codon before binding to the ribosome 
D)  when the mRNA circularizes, the poly(
A)  tail enables location of the initiation codon 
E)  the first AUG codon is found when the 40S subunit scans the mRNA from the 5' end

Question 7

Which of the following antibiotics mimics an aminoacyl-tRNA?

Accepted Answer

A)  chloramphenicol 
B)  erythromycin 
C)  penicillin 
D)  puromycin 
E)  streptomycin 
A)  chloramphenicol 
B)  erythromycin 
C)  penicillin 
D)  puromycin 
E)  streptomycin

Question 8

Which is NOT true of lectins such as ricin?

Accepted Answer

A)  They are naturally occurring, commonly from plants 
B)  They are proteins that bind carbohydrates 
C)  They block protein synthesis in prokaryotes by binding to the 16S subunit of the ribosome 
D)  They depurinate ribosomal RNAs in prokaryotes 
E)  They are endoglycosylases that target ribosomal adenines 
A)  They are naturally occurring, commonly from plants 
B)  They are proteins that bind carbohydrates 
C)  They block protein synthesis in prokaryotes by binding to the 16S subunit of the ribosome 
D)  They depurinate ribosomal RNAs in prokaryotes 
E)  They are endoglycosylases that target ribosomal adenines

Question 9

Use the structure below to answer the following questions  
-The D loop is represented by

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
E)  5 
A)  1 
B)  2 
C)  3 
D)  4 
E)  5

Question 10

The start codon is usually ______.

Accepted Answer

The answer of The start codon is usually ______....

Question 11

Which diagram depicts correctly a ribosome engaged in translation?

Accepted Answer

A)  a 
B)  b 
C)  c 
D)  d 
A)  a 
B)  b 
C)  c 
D)  d

Question 12

Translation termination requires ______ that recognize Stop codons.

Accepted Answer

The answer of Translation termination requires ______ that recognize Stop...

Question 13

Use the structure below to answer the following questions  
-Where is the anticodon in the following structure?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
E)  5 
A)  1 
B)  2 
C)  3 
D)  4 
E)  5

Question 14

EF-G is required for _____ as it binds to the ribosome in a manner similar to _____.

Accepted Answer

A)  translocation; the EF-Tu-tRNA complex 
B)  transpeptidation; the EF-Tu-GDP complex 
C)  transferase; an uncharged tRNA 
D)  transduction; an aminoacyl-tRNA 
E)  none of the above 
A)  translocation; the EF-Tu-tRNA complex 
B)  transpeptidation; the EF-Tu-GDP complex 
C)  transferase; an uncharged tRNA 
D)  transduction; an aminoacyl-tRNA 
E)  none of the above

Question 15

An open reading frame is defined by _____.

Accepted Answer

A)  a start and stop codon 
B)  homology with other species 
C)  placement on a genome map 
D)  presence of transposable elements 
E)  absence of highly repetitive sequences 
A)  a start and stop codon 
B)  homology with other species 
C)  placement on a genome map 
D)  presence of transposable elements 
E)  absence of highly repetitive sequences

Question 16

What type of bond connects the tRNA with its amino acid (AA)?

Accepted Answer

A)  ester between AA carboxylate and tRNA 3' hydroxyl 
B)  mixed anhydride of AA carboxylate and tRNA 3'phosphate 
C)  phosphoramide of AA amine and tRNA 3'phosphate 
D)  mixed anhydride of AA carboxylate and tRNA 5' phosphate 
E)  phosphoramide of AA amine and tRNA 5' phosphate 
A)  ester between AA carboxylate and tRNA 3' hydroxyl 
B)  mixed anhydride of AA carboxylate and tRNA 3'phosphate 
C)  phosphoramide of AA amine and tRNA 3'phosphate 
D)  mixed anhydride of AA carboxylate and tRNA 5' phosphate 
E)  phosphoramide of AA amine and tRNA 5' phosphate

Question 17

Which is true of codon wobble?
I. It occurs at codon position 2
II. It can lead to incorrect reading frame
III. It speeds protein synthesis
IV. It can result in weaker H bonding between codon and anticodon

Accepted Answer

A)  I only 
B)  II and III 
C)  III only 
D)  I and II 
E)  III and IV 
A)  I only 
B)  II and III 
C)  III only 
D)  I and II 
E)  III and IV

Question 18

Which amino acid is the first incorporated into a prokaryotic protein?

Accepted Answer

A)  N-formylthreonine 
B)  N-formylmethionine 
C)  N-formylaspartate 
D)  N-formylglutamine 
E)  N-formylcysteine 
A)  N-formylthreonine 
B)  N-formylmethionine 
C)  N-formylaspartate 
D)  N-formylglutamine 
E)  N-formylcysteine

Question 19

Which of the following explains why the aminoacyl-tRNA synthetase for isoleucine rarely incorporates valine despite the similar structure of these two amino acids?

Accepted Answer

A)  valine does not fit into the binding site for isoleucine 
B)  only leucine and isoleucine can fit in the active site of the enzyme 
C)  before incorporation, the enzyme methylates valine to make it into an isoleucine 
D)  the enzyme contains a proofreading site that removes valine from the tRNA 
E)  none of the above 
A)  valine does not fit into the binding site for isoleucine 
B)  only leucine and isoleucine can fit in the active site of the enzyme 
C)  before incorporation, the enzyme methylates valine to make it into an isoleucine 
D)  the enzyme contains a proofreading site that removes valine from the tRNA 
E)  none of the above

Question 20

Based on the structure shown below, which of the following correctly represents the sequence that would be present at the "XYZ"
Position?

Accepted Answer

A)  UGG 
B)  TGG 
C)  CCA 
D)  Cannot be determined from the given data. 
E)  None of the above is the correct sequence. 
A)  UGG 
B)  TGG 
C)  CCA 
D)  Cannot be determined from the given data. 
E)  None of the above is the correct sequence.

Exam 16: Protein

Within the ribosome during translation, the growing polypeptide chain is always attached to

Given the following anticodon, which mRNA codon would pair with it? 5'-IGC-3'

In the ribosome, interactions among the varied RNA molecules include

Which protein(s) important to translation can be considered guanine nucleotide exchange factors? I. eIF2 II. eIF3 III. EF-G IV. EF-Tu

Approximately what fraction of the mass of a ribosome is due to protein?

How is the initiation codon found in eukaryotic translation?

Which of the following antibiotics mimics an aminoacyl-tRNA?

Which is NOT true of lectins such as ricin?

Use the structure below to answer the following questions -The D loop is represented by

The start codon is usually ______.

Which diagram depicts correctly a ribosome engaged in translation?

Translation termination requires ______ that recognize Stop codons.

Use the structure below to answer the following questions -Where is the anticodon in the following structure?

EF-G is required for _____ as it binds to the ribosome in a manner similar to _____.

An open reading frame is defined by _____.

What type of bond connects the tRNA with its amino acid (AA)?

Which is true of codon wobble? I. It occurs at codon position 2 II. It can lead to incorrect reading frame III. It speeds protein synthesis IV. It can result in weaker H bonding between codon and anticodon

Which amino acid is the first incorporated into a prokaryotic protein?

Which of the following explains why the aminoacyl-tRNA synthetase for isoleucine rarely incorporates valine despite the similar structure of these two amino acids?

Based on the structure shown below, which of the following correctly represents the sequence that would be present at the "XYZ" Position?

The Chemical Foundations of Biochemistry

Nucleic Acids

Proteins I

Proteins Iienzymes

Membranes and an Introduction to Signal Transduction

Carbohydrates I

The Common Catabolic Pathway

Carbohydrates II

Lipids I

Lipids II

Amine Metabolism

Metabolism Integration

Nucleotide Deoxynucleotide Metabolism

Dna Replication, Damage and Repair

Rna Synthesis

Control of Gene

Determination of Macromolecular Structure

Allosterism and Receptor-Ligand

Designer Proteins and Protein Folding

Biomolecule Purification

Bioinformatics and Omics

Signal

Protein Trafficking

Photosynthesis Nitrogen

Filters

EF-G is required for _ as it binds to the ribosome in a manner similar to _.