Question 1

A minimum of six general transcription factors are required for the recruitment of RNA polymerase II.

Accepted Answer

A) True 
 B)False

Question 2

An internal channel between the $\beta$and $\beta$' subunits contains the bacterial RNA polymerase active site.

Accepted Answer

A) True 
 B)False

Question 3

The first step in the formation of a transcription complex for mRNA transcription is the binding of _______ to the TATA box.

Accepted Answer

A)  TFIA 
B)  TFIIA 
C)  TFIIIA 
D)  TFIID 
A)  TFIA 
B)  TFIIA 
C)  TFIIIA 
D)  TFIID

Question 4

Which step is considered the final aspect of processing an RNA molecule?

Accepted Answer

A)  Addition of the 5′ cap 
B)  RNA editing 
C)  Degradation in the cytoplasm 
D)  Splicing 
A)  Addition of the 5′ cap 
B)  RNA editing 
C)  Degradation in the cytoplasm 
D)  Splicing

Question 5

What is the most common form of nuclear RNA editing in mammals?

Accepted Answer

Deamination of adeno

Question 6

Processing of the 5′ end of pre-tRNAs involves cleavage by an enzyme called _______.

Accepted Answer

The answer of Processing of the 5′ end of pre-tRNAs...

Question 7

rRNA modifications are mediated by

Accepted Answer

A)  general transcription factors. 
B)  miRNAs. 
C)  snoRNPs. 
D)  Mediator. 
A)  general transcription factors. 
B)  miRNAs. 
C)  snoRNPs. 
D)  Mediator.

Question 8

Explain the role of Meditator in transcription.

Accepted Answer

Mediator is required for transcription w

Question 9

Termination of transcription in E. coli is signaled by

Accepted Answer

A)  formation of a stem-loop structure in the RNA. 
B)  binding of Rho protein to the end of the mRNA. 
C)  binding of a sigma ($\sigma$) factor to the end of the mRNA. 
D)  an inverted GC-rich sequence followed by seven A residues. 
A)  formation of a stem-loop structure in the RNA. 
B)  binding of Rho protein to the end of the mRNA. 
C)  binding of a sigma ($\sigma$) factor to the end of the mRNA. 
D)  an inverted GC-rich sequence followed by seven A residues.

Question 10

The prokaryotic cells most commonly used to study transcription and translation are from

Accepted Answer

A)  E. coli. 
B)  B. subtilis. 
C)  S. cerevisiae. 
D)  D. discoideum. 
A)  E. coli. 
B)  B. subtilis. 
C)  S. cerevisiae. 
D)  D. discoideum.

Question 11

Which snRNA is responsible for recognition of the 5′ splice site consensus sequence in mRNA splicing?

Accepted Answer

A)  U1 
B)  U4 
C)  U5 
D)  U6 
A)  U1 
B)  U4 
C)  U5 
D)  U6

Question 12

Why are some RNAs considered to be self-splicing?

Accepted Answer

They can catalyze th

Question 13

The subunit of TFIID that is responsible for binding specifically to the TATA box is known as _______.

Accepted Answer

TATA-bindi

Question 14

During splicing, pre-mRNAs go through an intermediate stage when they are shaped like

Accepted Answer

A)  a lariat. 
B)  a circle. 
C)  the Greek letter theta ($\sigma$). 
D)  a cross. 
A)  a lariat. 
B)  a circle. 
C)  the Greek letter theta ($\sigma$). 
D)  a cross.

Question 15

In eukaryotic cells, different mRNAs have different half-lives, and therefore are degraded at different rates. What is the usefulness of this wide range of half-lives?

Accepted Answer

Unstable mRNAs frequently code for regul

Question 16

Which statement about transcription of ribosomal RNA is false?

Accepted Answer

A)  Ribosomal RNA is transcribed by RNA polymerase I. 
B)  A single pre-RNA gives rise to the 18S, 5.8S, and 28S rRNAs. 
C)  TBP binds the TATA sequences in the promoter of the ribosomal gene. 
D)  Two transcription factors, UBF and SL1, bind the RNA gene promoter and recruit polymerase I to form the initiation complex. 
A)  Ribosomal RNA is transcribed by RNA polymerase I. 
B)  A single pre-RNA gives rise to the 18S, 5.8S, and 28S rRNAs. 
C)  TBP binds the TATA sequences in the promoter of the ribosomal gene. 
D)  Two transcription factors, UBF and SL1, bind the RNA gene promoter and recruit polymerase I to form the initiation complex.

Question 17

Which of the following regulates degradation of mRNAs within a cell?

Accepted Answer

A)  Growth factors 
B)  miRNAs 
C)  Hormones 
D)  All of the above 
A)  Growth factors 
B)  miRNAs 
C)  Hormones 
D)  All of the above

Question 18

Explain how the 5′ cap is formed in messenger RNA.

Accepted Answer

The 5′ cap is formed by the addition of

Question 19

A poly-A tail is added to an mRNA by

Accepted Answer

A)  RNA polymerase, which reads a string of complementary dTs at the end of the gene. 
B)  poly-A polymerase, which adds A's sequentially to the end of the transcript. 
C)  poly-A transferase, which adds a pre-made poly-A sequence to the end of the transcript. 
D)  poly-A correctase, which recognizes an AAUAAA signal at the end of the message and changes the U to an A. 
A)  RNA polymerase, which reads a string of complementary dTs at the end of the gene. 
B)  poly-A polymerase, which adds A's sequentially to the end of the transcript. 
C)  poly-A transferase, which adds a pre-made poly-A sequence to the end of the transcript. 
D)  poly-A correctase, which recognizes an AAUAAA signal at the end of the message and changes the U to an A.

Question 20

What feature is often found on rapidly degraded mRNAs?

Accepted Answer

Rapidly degraded mRNAs often c

A minimum of six general transcription factors are required for the recruitment of RNA polymerase II.

An internal channel between the $\beta$ and $\beta$ ' subunits contains the bacterial RNA polymerase active site.

The first step in the formation of a transcription complex for mRNA transcription is the binding of _______ to the TATA box.

Which step is considered the final aspect of processing an RNA molecule?

What is the most common form of nuclear RNA editing in mammals?

Processing of the 5′ end of pre-tRNAs involves cleavage by an enzyme called _______.

rRNA modifications are mediated by

Explain the role of Meditator in transcription.

Termination of transcription in E. coli is signaled by

The prokaryotic cells most commonly used to study transcription and translation are from

Which snRNA is responsible for recognition of the 5′ splice site consensus sequence in mRNA splicing?

Why are some RNAs considered to be self-splicing?

The subunit of TFIID that is responsible for binding specifically to the TATA box is known as _______.

During splicing, pre-mRNAs go through an intermediate stage when they are shaped like

In eukaryotic cells, different mRNAs have different half-lives, and therefore are degraded at different rates. What is the usefulness of this wide range of half-lives?

Which statement about transcription of ribosomal RNA is false?

Which of the following regulates degradation of mRNAs within a cell?

Explain how the 5′ cap is formed in messenger RNA.

A poly-A tail is added to an mRNA by

What feature is often found on rapidly degraded mRNAs?

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

Exam 8: RNA Synthesis and Processing

A minimum of six general transcription factors are required for the recruitment of RNA polymerase II.

An internal channel between the β\betaβ and β\betaβ ' subunits contains the bacterial RNA polymerase active site.

The first step in the formation of a transcription complex for mRNA transcription is the binding of _______ to the TATA box.

Which step is considered the final aspect of processing an RNA molecule?

What is the most common form of nuclear RNA editing in mammals?

Processing of the 5′ end of pre-tRNAs involves cleavage by an enzyme called _______.

rRNA modifications are mediated by

Explain the role of Meditator in transcription.

Termination of transcription in E. coli is signaled by

The prokaryotic cells most commonly used to study transcription and translation are from

Which snRNA is responsible for recognition of the 5′ splice site consensus sequence in mRNA splicing?

Why are some RNAs considered to be self-splicing?

The subunit of TFIID that is responsible for binding specifically to the TATA box is known as _______.

During splicing, pre-mRNAs go through an intermediate stage when they are shaped like

In eukaryotic cells, different mRNAs have different half-lives, and therefore are degraded at different rates. What is the usefulness of this wide range of half-lives?

Which statement about transcription of ribosomal RNA is false?

Which of the following regulates degradation of mRNAs within a cell?

Explain how the 5′ cap is formed in messenger RNA.

A poly-A tail is added to an mRNA by

What feature is often found on rapidly degraded mRNAs?

An Overview of Cells and Cell Research

Molecules and Membranes

Bioenergetics and Metabolism

Fundamentals of Molecular Biology

Genomics, Proteomics, and Systems Biology

Genes and Genomes

Replication, Maintenance, and Rearrangements of Genomic Dna

Transcriptional Regulation and Epigenetics

Protein Synthesis, Processing, and Regulation

The Nucleus

Protein Sorting and Transport

Mitochondria, Chloroplasts, and Peroxisomes

The Cytoskeleton and Cell Movement

The Plasma Membrane

Cell Walls, the Extracellular Matrix, and Cell Interactions

Cell Signaling

The Cell Cycle

Cell Death and Cell Renewal

Cancer

Filters

An internal channel between the $\beta$ and $\beta$ ' subunits contains the bacterial RNA polymerase active site.