Exam 5: Neoplasia

Which is the most common radiation-induced cancer in humans?

Pseudomyxoma peritonei is a complication of which tumor?

Germ line mutation of the Von Hippel-Lindau (VHL) gene is associated with formation of retinal angiomas and

Matrix metalloproteinases secreted by tumor cells are important for which feature of malignant tumors?

Which of the following tumors occurs most often in the ovary?

Clubbing of the digits, periosteal new bone formation on the metatarsals, metacarpals, and proximal phalanges, and arthritis of adjacent joints is a paraneoplastic syndrome most often associated with carcinoma of the

Homogeneous staining regions (HSR) of chromosome 2p, the site of the N-mycgene, are adverse prognostic signs if found in neuroblastoma cells. HRS are evidence of gene

In which cell function is BRCA1, a gene mutated in women with familial breast carcinoma, involved?

Which mechanism affecting the genes or chromosomes accounts for the activation of the c-myc protooncogene in Burkitt lymphoma cells?

Microsatellite instability, a marker of DNA mismatch repair, is typically found in

Helicobacter pylori infection predisposes to formation of gastric tumors, but the association between the bacterial infection and a gastric tumor is the strongest for

Which enzymes in the liver account for the activation of most procarcinogens into carcinogens?

Germ line mutation of E-cadherin is found in familial cases of

Which one of the following carcinomas is locally invasive but rarely forms metastases in lymph nodes and distant sites?