Exam 15: Liver, Gallbladder, and Biliary Tract

A 55-year-old man known to have drunk a half liter of gin daily for the past 15 years died due to ruptured esophageal varices and massive bleeding. At autopsy, the liver was nodular and

Ascending cholangitis is most often caused by

HELLP syndrome (hemolysis, elevated liver enzymes, low platelets) occurs typically in

Centrolobular necrosis is typical of intoxication with

This liver tumor nodule, measuring 6 cm in diameter, was seen on a computerized tomography (CT) scan of a 40-year-old man. Initially, the nodule was considered to be benign, but when it became painful, the patient decided to have it removed. Histologically, it was composed of well-differentiated hepatocytes, whereas the central scar and the fibrous septa contained proliferating bile ducts. This nodule is most likely

Which of the following drugs causes microvesicular fatty change of the liver?

These gallstones surgically removed along with the gallbladder of a 50-year-old obese woman are composed predominantly of

Antibodies to mitochondrial dihydrolipoamide acetyltransferase are typically found in 90% of patients who have

Copper accumulates in the liver in Wilson disease but stainable copper also can be seen in liver biopsies of patients who have

Which of the following types of hepatocellular carcinoma occurs in young adults, is unrelated to cirrhosis, and has a much better prognosis (i.e., a 60% 5-year survival rate)?

The most common cause of cirrhosis unrelated to alcohol, viral hepatitis, or metabolic diseases (i.e., the so-called "cryptogenic cirrhosis") is

Transplacental infection of the fetus will most often occur in women who have been infected with which hepatotropic virus?

An obese 50-year-old woman, whose height is 5 ft 4 in (160 cm) and weight is 220 lb (100 kg), decided to lose weight. She lost 45 lb (approximately 20 kg) over a period of 6 months, and then had an attack of biliary colic and required a cholecystectomy. The gallbladder stones identified by the pathologist were most likely

Cryoglobulinemia is found in chronic hepatitis caused by which hepatotropic virus?

What is the most common cause of neonatal cholestasis?

A mutation of the gene encoding the hepatic enzyme bilirubin uridine diphosphate-glucuronyltransferase (UGT1A1) associated with congenital jaundice and a complete absence of UGT1A1 is called

Peliosis hepatis is a form of primary hepatic sinusoidal dilatation and intrasinusoidal blood stagnation most often caused by

Which genetic liver disease results from the mutation of multidrug resistance protein 2 (MRP2) and is characterized by massive accumulation of pigmentary granules in hepatocytes and dark discoloration of the liver?