Question 1

If the pH of a protein solution becomes very low, the protein molecules will become polyanions.

Accepted Answer

A) True 
 B)False

Question 2

Which of the following correctly matches the amino acid with its three-letter abbreviation?

Accepted Answer

A) tryptophan: try 
B) asparagine: asp 
C) cysteine: cys 
D) isoleucine: iso 
E) valine: van 
A) tryptophan: try 
B) asparagine: asp 
C) cysteine: cys 
D) isoleucine: iso 
E) valine: van

Question 3

What determines the primary structure of a protein?

Accepted Answer

A) α-helix 
B) hydrogen bonding between amide hydrogens and carboxyl oxygens 
C) amino acid sequence of the chain 
D) ionic bonds between the R group of oppositely charged amino acids 
E) None of the choices are correct. 
A) α-helix 
B) hydrogen bonding between amide hydrogens and carboxyl oxygens 
C) amino acid sequence of the chain 
D) ionic bonds between the R group of oppositely charged amino acids 
E) None of the choices are correct.

Question 4

What two functional groups characterize the amino acids found in human proteins?

Accepted Answer

A) a carboxylate group and an amino group 
B) an amide group and an amino group 
C) a primary amine group and an aldehyde group 
D) a primary amine group and a ketone group 
E) an amino group and an aldehyde group 
A) a carboxylate group and an amino group 
B) an amide group and an amino group 
C) a primary amine group and an aldehyde group 
D) a primary amine group and a ketone group 
E) an amino group and an aldehyde group

Question 5

What disease results from a deficiency of vitamin C?

Accepted Answer

A) diabetes 
B) sickle cell 
C) scurvy 
D) Alzheimer?s 
E) lactose intolerance 
A) diabetes 
B) sickle cell 
C) scurvy 
D) Alzheimer?s 
E) lactose intolerance

Question 6

Which of the following properly represents the dipeptide with the primary structure Ala-Cys?

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 7

How do the primary structures of normal hemoglobin and sickle cell hemoglobin differ?

Accepted Answer

A) A glutamic acid residue in normal hemoglobin is replaced by a valine residue in sickle cell hemoglobin. 
B) A valine acid residue in normal hemoglobin is replaced by a glutamic acid residue in sickle cell hemoglobin. 
C) There are four heme groups in normal hemoglobin whereas there are only three heme groups in sickle cell hemoglobin. 
D) There are three heme groups in normal hemoglobin whereas there are 4 heme groups in sickle cell hemoglobin. 
E) Both A and C are correct. 
A) A glutamic acid residue in normal hemoglobin is replaced by a valine residue in sickle cell hemoglobin. 
B) A valine acid residue in normal hemoglobin is replaced by a glutamic acid residue in sickle cell hemoglobin. 
C) There are four heme groups in normal hemoglobin whereas there are only three heme groups in sickle cell hemoglobin. 
D) There are three heme groups in normal hemoglobin whereas there are 4 heme groups in sickle cell hemoglobin. 
E) Both A and C are correct.

Question 8

What essential type of reaction of collagen requires the presence of vitamin C before it will occur?

Accepted Answer

A) hydration 
B) hydrolysis 
C) hydrogenation 
D) hydroxylation 
E) peptidation 
A) hydration 
B) hydrolysis 
C) hydrogenation 
D) hydroxylation 
E) peptidation

Question 9

Which term best describes the relationship between L-alanine and D-alanine?

Accepted Answer

A) enantiomers 
B) constitutional isomers 
C) meso 
D) diastereomer 
E) identical 
A) enantiomers 
B) constitutional isomers 
C) meso 
D) diastereomer 
E) identical

Question 10

When a protein undergoes hydrolysis, which of the following things occur?

Accepted Answer

A) Peptide bonds are broken, and individual amino acids are released. 
B) The protein folds into its functional, three-dimensional shape. 
C) Water adds across each double bond that is present to give an alcohol. 
D) New amino acids are joined to the growing protein chain. 
E) Unsaturation in the side chain R groups is removed. 
A) Peptide bonds are broken, and individual amino acids are released. 
B) The protein folds into its functional, three-dimensional shape. 
C) Water adds across each double bond that is present to give an alcohol. 
D) New amino acids are joined to the growing protein chain. 
E) Unsaturation in the side chain R groups is removed.

Question 11

What two types of secondary structure are depicted in the ribbon diagram of the protein shown below?

Accepted Answer

A) β-spirals and α-turns 
B) double stranded helices and β-arrays 
C) random coils and β-arrays 
D) α-helices and β-pleated sheets 
E) α-spirals and β-turns 
A) β-spirals and α-turns 
B) double stranded helices and β-arrays 
C) random coils and β-arrays 
D) α-helices and β-pleated sheets 
E) α-spirals and β-turns

Question 12

What is the most common type of secondary structure in a protein?

Accepted Answer

A) random coil 
B) β-pleated sheet 
C) double helix 
D) α-helix 
E) globular 
A) random coil 
B) β-pleated sheet 
C) double helix 
D) α-helix 
E) globular

Question 13

Hydroxyapatite is a polymer of collagen and minerals.

Accepted Answer

A) True 
 B)False

Question 14

What is the term for the state of a protein when its organized structure has become completely disorganized?

Accepted Answer

A) hydrolyzed 
B) isomerized 
C) globular 
D) denatured 
E) fibrous 
A) hydrolyzed 
B) isomerized 
C) globular 
D) denatured 
E) fibrous

Question 15

What level(s) of protein structure is/are created in part by disulfide bridges?

Accepted Answer

A) primary 
B) secondary 
C) tertiary 
D) quaternary 
E) All of the choices are correct. 
A) primary 
B) secondary 
C) tertiary 
D) quaternary 
E) All of the choices are correct.

Question 16

Which statement is FALSE?

Accepted Answer

A) Hydrophobic amino acids have nonpolar side chains. 
B) Hydrophobic amino acids are usually positively or negatively charged. 
C) Hydrophobic amino acids are found in the interior of proteins. 
D) Hydrophilic amino acids can be subdivided into categories based upon their charge at pH of 7. 
E) Hydrophilic amino acids have polar side chains. 
A) Hydrophobic amino acids have nonpolar side chains. 
B) Hydrophobic amino acids are usually positively or negatively charged. 
C) Hydrophobic amino acids are found in the interior of proteins. 
D) Hydrophilic amino acids can be subdivided into categories based upon their charge at pH of 7. 
E) Hydrophilic amino acids have polar side chains.

Question 17

Coagulation occurs when a protein unfolds and becomes entangled.

Accepted Answer

A) True 
 B)False

Question 18

What protein is the oxygen storage protein of the skeletal muscles?

Accepted Answer

A) insulin 
B) collagen 
C) myoglobin 
D) albumin 
E) hemoglobin 
A) insulin 
B) collagen 
C) myoglobin 
D) albumin 
E) hemoglobin

Question 19

How many different amino acids make up the proteins found in the human body?

Accepted Answer

A) 4 
B) 16 
C) 20 
D) 125 
E) This has not yet been determined. 
A) 4 
B) 16 
C) 20 
D) 125 
E) This has not yet been determined.

Question 20

Which structural protein is found in bone, tendon, and skin?

Accepted Answer

A) collagen 
B) fibrinogen 
C) albumin 
D) keratin 
E) insulin 
A) collagen 
B) fibrinogen 
C) albumin 
D) keratin 
E) insulin

Exam 18: Protein Structure and Function

If the pH of a protein solution becomes very low, the protein molecules will become polyanions.

Which of the following correctly matches the amino acid with its three-letter abbreviation?

What determines the primary structure of a protein?

What two functional groups characterize the amino acids found in human proteins?

What disease results from a deficiency of vitamin C?

Which of the following properly represents the dipeptide with the primary structure Ala-Cys?

How do the primary structures of normal hemoglobin and sickle cell hemoglobin differ?

What essential type of reaction of collagen requires the presence of vitamin C before it will occur?

Which term best describes the relationship between L-alanine and D-alanine?

When a protein undergoes hydrolysis, which of the following things occur?

What two types of secondary structure are depicted in the ribbon diagram of the protein shown below?

What is the most common type of secondary structure in a protein?

Hydroxyapatite is a polymer of collagen and minerals.

What is the term for the state of a protein when its organized structure has become completely disorganized?

What level(s) of protein structure is/are created in part by disulfide bridges?

Which statement is FALSE?

Coagulation occurs when a protein unfolds and becomes entangled.

What protein is the oxygen storage protein of the skeletal muscles?

How many different amino acids make up the proteins found in the human body?

Which structural protein is found in bone, tendon, and skin?

Chemistry:methods and Measurement

The Structure of the Atom and the Periodic Table

Structure and Properties of Ionic and Covalent Compounds

Calculations, Chemical Changes, and the Chemical Equation

States of Matter- Gases, Liquids, and Solids

Solutions

Energy, Rate and Equilibrium

Acids and Bases

The Nucleus, Radioactivity, and Nuclear Medicine

An Introduction to Organic Chemistry- the Saturated Hydrocarbons

The Unsaturated Hydrocarbons- Alkenes, Alkynes, and Aromatics

Alcohols, Phenols, Thiols, and Ethers

Aldehydes and Ketones

Carboxylic Acids and Carboxylic Acid Derivatives

Amines and Amides

Carbohydrates

Lipids and Their Functions in Biochemical Systems

Enzymes

Introduction to Molecular Genetics

Carbohydrate Metabolism

Aerobic Respiration and Energy Production

Fatty Acid Metabolism

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