Question 1

The mRNA for which of the following proteins lacks a poly(A)tail?

Accepted Answer

A) glutamine 
B) catalase 
C) collagen 
D) histones 
E) non-histone acidic proteins 
A) glutamine 
B) catalase 
C) collagen 
D) histones 
E) non-histone acidic proteins

Question 2

RNAi or dsRNA-mediated RNA interference is an example of a broader phenomenon that occurs widely in eukaryotes called __________.

Accepted Answer

A) RNA activation 
B) RNA ascension 
C) RNA silencing 
D) RNA sussuration 
E) RNA quieting 
A) RNA activation 
B) RNA ascension 
C) RNA silencing 
D) RNA sussuration 
E) RNA quieting

Question 3

What molecule is TFIIH known to phosphorylate?

Accepted Answer

A) a G protein 
B) RNA polymerase II 
C) RNA polymerase IV 
D) peptidyltransferase 
E) DNA helicase 
A) a G protein 
B) RNA polymerase II 
C) RNA polymerase IV 
D) peptidyltransferase 
E) DNA helicase

Question 4

A larger S value for an RNA specifically indicates that the RNA __________.

Accepted Answer

A) migrates more rapidly through a field of force during centrifugation 
B) migrates less rapidly through a field of force during centrifugation 
C) migrates more rapidly through a field of force during gel filtration 
D) migrates more rapidly through a field of force during SDS polyacrylamide gel electrophoresis 
E) migrates less rapidly through a field of force during SDS polyacrylamide gel electrophoresis 
A) migrates more rapidly through a field of force during centrifugation 
B) migrates less rapidly through a field of force during centrifugation 
C) migrates more rapidly through a field of force during gel filtration 
D) migrates more rapidly through a field of force during SDS polyacrylamide gel electrophoresis 
E) migrates less rapidly through a field of force during SDS polyacrylamide gel electrophoresis

Question 5

You incubate eukaryotic cells for 30 minutes in 3H-uridine and then immediately kill the cells and extract the RNA.Where does the radiolabel appear after this experiment?

Accepted Answer

A) in larger RNAs in the cytoplasm 
B) in smaller RNAs in the mitochondria 
C) in smaller RNAs in the cytoplasm 
D) in larger RNAs in the mitochondria 
E) in moderately sized RNAs in the Golgi complex 
A) in larger RNAs in the cytoplasm 
B) in smaller RNAs in the mitochondria 
C) in smaller RNAs in the cytoplasm 
D) in larger RNAs in the mitochondria 
E) in moderately sized RNAs in the Golgi complex

Question 6

The snoRNA genes are found in the ______ of genes coding for polypeptides involved in _______.

Accepted Answer

A) exons,structural genes 
B) introns,ribosome assembly and function 
C) exons,ribosome assembly and function 
D) introns,structural genes 
E) introns,RNA synthesis 
A) exons,structural genes 
B) introns,ribosome assembly and function 
C) exons,ribosome assembly and function 
D) introns,structural genes 
E) introns,RNA synthesis

Question 7

It has been discovered that some mRNAs have a signal that causes the ribosome to change its reading frame by backing up or moving ahead one base.This can,in some cases,defend against a frameshift mutation.Such a sequence is called a(n)_________.

Accepted Answer

A) recentering signal 
B) recoding signal 
C) acentric signal 
D) acentric sequence 
E) allopatric sequence 
A) recentering signal 
B) recoding signal 
C) acentric signal 
D) acentric sequence 
E) allopatric sequence

Question 8

In what direction is mRNA produced?

Accepted Answer

A) 3' to 5' direction 
B) 5' to 3' direction 
C) N-terminal to C-terminal direction 
D) C-terminal to N-terminal direction 
E) N-terminal to 3' direction 
A) 3' to 5' direction 
B) 5' to 3' direction 
C) N-terminal to C-terminal direction 
D) C-terminal to N-terminal direction 
E) N-terminal to 3' direction

Question 9

Which strand of the double-stranded siRNA is cut in two and then dissociates from the pre-RISC?

Accepted Answer

A) the active strand 
B) the passenger strand 
C) the siRNA strand 
D) the pedestrian strand 
E) the silencer strand 
A) the active strand 
B) the passenger strand 
C) the siRNA strand 
D) the pedestrian strand 
E) the silencer strand

Question 10

The _______ is located about 10 bases upstream from the initiation site.It has the consensus sequence ______ and is responsible for identifying the precise nucleotide at which ________ begins.

Accepted Answer

A) Pribnow box,TATAAT,transcription 
B) Pribnow box,TTGACA,transcription 
C) Pribnow box,TATAAT,translation 
D) Portnoy box,TATAAT,transcription 
E) Portnoy box,TATAAT,translation 
A) Pribnow box,TATAAT,transcription 
B) Pribnow box,TTGACA,transcription 
C) Pribnow box,TATAAT,translation 
D) Portnoy box,TATAAT,transcription 
E) Portnoy box,TATAAT,translation

Question 11

Where are the snoRNAs encoded?

Accepted Answer

A) within their own genes 
B) within the exons of other genes 
C) within the telomeres 
D) within the intervening sequences of other genes 
E) within the intervening sequences of their own genes 
A) within their own genes 
B) within the exons of other genes 
C) within the telomeres 
D) within the intervening sequences of other genes 
E) within the intervening sequences of their own genes

Question 12

A person suffers from a genetic disease similar to those described by Archibald Garrod.A substance D builds up in his bloodstream and spills into his urine.Look at the metabolic pathway below.At which step in the pathway does the inborn error of metabolism in this person occur?

Accepted Answer

Enzyme 4 (E4)is not working pr

Question 13

Another name for protein synthesis is _________.

Accepted Answer

A) transcription 
B) transition 
C) transubstantiation 
D) translation 
E) transition state 
A) transcription 
B) transition 
C) transubstantiation 
D) translation 
E) transition state

Question 14

Which of the phenomena below is responsible for the ability of one gene to code for more than one polypeptide?

Accepted Answer

A) transcription 
B) alternative splicing 
C) transposition 
D) hybridization 
E) exon shuffling 
A) transcription 
B) alternative splicing 
C) transposition 
D) hybridization 
E) exon shuffling

Question 15

The site on DNA to which RNA polymerases bind before initiating transcription is called the ______.

Accepted Answer

A) terminator 
B) operator 
C) promoter 
D) enhancer 
E) silencer 
A) terminator 
B) operator 
C) promoter 
D) enhancer 
E) silencer

Question 16

In an experiment,you purify a cysteine-charged tRNA and chemically alter the amino acid attached to it converting it to alanine.You place this charged tRNA in a cell-free protein-synthesizing system with all of the other charged tRNAs,mRNA and other substances needed for the synthesis of proteins.What,if anything,will be different from the normal protein coded for by the mRNA in the mixture?

Accepted Answer

The protein will be identical

Question 17

Which scientist is best known for his work on sickle cell anemia and proving the mechanism that causes the disease?

Accepted Answer

A) Charles Darwin 
B) Archibald Garrod 
C) George Beadle 
D) Vernon Ingram 
E) James Watson 
A) Charles Darwin 
B) Archibald Garrod 
C) George Beadle 
D) Vernon Ingram 
E) James Watson

Question 18

Who was the first to report that certain rare inherited diseases were caused by the absence of specific enzymes?

Accepted Answer

A) Charles Darwin 
B) Archibald Garrod 
C) George Beadle 
D) Vernon Ingram 
E) James Watson 
A) Charles Darwin 
B) Archibald Garrod 
C) George Beadle 
D) Vernon Ingram 
E) James Watson

Question 19

How is the RISC directed to the target mRNA that it is destined to destroy?

Accepted Answer

A) The ribonuclease slicer directs the RISC to the cleavage site. 
B) The single-stranded siRNA is complementary to the target mRNA and directs the RISC to it. 
C) The passenger strand acts like a guide to direct the RISC to the target. 
D) The siRNA is complementary to the slicer ribonuclease. 
E) The siRNA is magnetically attracted to the target mRNA. 
A) The ribonuclease slicer directs the RISC to the cleavage site. 
B) The single-stranded siRNA is complementary to the target mRNA and directs the RISC to it. 
C) The passenger strand acts like a guide to direct the RISC to the target. 
D) The siRNA is complementary to the slicer ribonuclease. 
E) The siRNA is magnetically attracted to the target mRNA.

Question 20

Heterogeneous nuclear RNAs are _________.

Accepted Answer

A) tRNA precursors 
B) mRNA precursors 
C) rRNA precursors 
D) snoRNA precursors 
E) mature snRNAs 
A) tRNA precursors 
B) mRNA precursors 
C) rRNA precursors 
D) snoRNA precursors 
E) mature snRNAs

The mRNA for which of the following proteins lacks a poly(A)tail?

RNAi or dsRNA-mediated RNA interference is an example of a broader phenomenon that occurs widely in eukaryotes called __________.

What molecule is TFIIH known to phosphorylate?

A larger S value for an RNA specifically indicates that the RNA __________.

You incubate eukaryotic cells for 30 minutes in 3H-uridine and then immediately kill the cells and extract the RNA.Where does the radiolabel appear after this experiment?

The snoRNA genes are found in the of genes coding for polypeptides involved in _.

It has been discovered that some mRNAs have a signal that causes the ribosome to change its reading frame by backing up or moving ahead one base.This can,in some cases,defend against a frameshift mutation.Such a sequence is called a(n)_________.

In what direction is mRNA produced?

Which strand of the double-stranded siRNA is cut in two and then dissociates from the pre-RISC?

The _ is located about 10 bases upstream from the initiation site.It has the consensus sequence and is responsible for identifying the precise nucleotide at which ____ begins.

Where are the snoRNAs encoded?

A person suffers from a genetic disease similar to those described by Archibald Garrod.A substance D builds up in his bloodstream and spills into his urine.Look at the metabolic pathway below.At which step in the pathway does the inborn error of metabolism in this person occur?

Another name for protein synthesis is _________.

Which of the phenomena below is responsible for the ability of one gene to code for more than one polypeptide?

The site on DNA to which RNA polymerases bind before initiating transcription is called the ______.

Which scientist is best known for his work on sickle cell anemia and proving the mechanism that causes the disease?

Who was the first to report that certain rare inherited diseases were caused by the absence of specific enzymes?

How is the RISC directed to the target mRNA that it is destined to destroy?

Heterogeneous nuclear RNAs are _________.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics, Enzymes, and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Exam 11: Gene Expression: From Transcription to Translation

The mRNA for which of the following proteins lacks a poly(A)tail?

RNAi or dsRNA-mediated RNA interference is an example of a broader phenomenon that occurs widely in eukaryotes called __________.

What molecule is TFIIH known to phosphorylate?

A larger S value for an RNA specifically indicates that the RNA __________.

You incubate eukaryotic cells for 30 minutes in 3H-uridine and then immediately kill the cells and extract the RNA.Where does the radiolabel appear after this experiment?

The snoRNA genes are found in the ______ of genes coding for polypeptides involved in _______.

It has been discovered that some mRNAs have a signal that causes the ribosome to change its reading frame by backing up or moving ahead one base.This can,in some cases,defend against a frameshift mutation.Such a sequence is called a(n)_________.

In what direction is mRNA produced?

Which strand of the double-stranded siRNA is cut in two and then dissociates from the pre-RISC?

The _______ is located about 10 bases upstream from the initiation site.It has the consensus sequence ______ and is responsible for identifying the precise nucleotide at which ________ begins.

Where are the snoRNAs encoded?

A person suffers from a genetic disease similar to those described by Archibald Garrod.A substance D builds up in his bloodstream and spills into his urine.Look at the metabolic pathway below.At which step in the pathway does the inborn error of metabolism in this person occur?

Another name for protein synthesis is _________.

Which of the phenomena below is responsible for the ability of one gene to code for more than one polypeptide?

The site on DNA to which RNA polymerases bind before initiating transcription is called the ______.

Which scientist is best known for his work on sickle cell anemia and proving the mechanism that causes the disease?

Who was the first to report that certain rare inherited diseases were caused by the absence of specific enzymes?

How is the RISC directed to the target mRNA that it is destined to destroy?

Heterogeneous nuclear RNAs are _________.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics, Enzymes, and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, Function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

The Immune Response

Techniques in Cell and Molecular Biology

Filters

The snoRNA genes are found in the of genes coding for polypeptides involved in _.

The _ is located about 10 bases upstream from the initiation site.It has the consensus sequence and is responsible for identifying the precise nucleotide at which ____ begins.