Exam 11: Gene Expression: From Transcription to Translation

What difference between sickle cell and normal hemoglobin is apparently responsible for all of the symptoms associated with sickle cell anemia?

What are the three distinct activities of protein synthesis in the correct order?

What is probably responsible for driving the conformational shift that is required for the release of the IF2-GDP initiation factor from the initiation complex?

Where is the pre-miRNA converted to miRNA by Dicer?

Which of the following binds to the TATA box?

What is the supposed function of the loops in tRNAs?

A cluster of genes coding for tRNAs is often referred to as ______.

The promoter for tRNA genes (tDNA)is located ________.

What amino acid is converted to selenocysteine after its attachment to its tRNA?

What features set pre-rRNAs apart from other RNA transcripts?

The genetic code has 64 codons,while there are only 20 amino acids.Thus,some amino acids are coded for by more than one codon.As a result,the genetic code is said to be ________.

What is always the first amino acid incorporated at the N-terminus of a nascent polypeptide chain?

What kind of DNA is the DNA that codes for rRNA?

With what protein does the double-stranded miRNA become associated? The RNA duplex then is disassembled and one of the single strands is incorporated into a RISC complex.

Why has the One Gene - One Polypeptide hypothesis had to be modified?

Which enzyme,also responsible for siRNA formation,carves miRNAs from their double-stranded,fold-back RNA precursor (pre-miRNA)?

Most of the cellular RNA is in what form?

A small RNA encoded by the lin-4 gene was found in the nematode C.elegans.It was nearly complementary to segments in ________.These small RNAs were able to bind to the complementary mRNA blocking its translation,which apparently triggers a transition to the next developmental stage.

In mammalian cells,radiolabeled methyl groups appear first in what size RNA molecule that is a precursor to rRNA?

The chromosome regions containing rDNA are called ________.