Question 1

Which of the following aryl amines is the strongest base?

Accepted Answer

A) Aniline 
B) p-Trimethylammonium aniline 
C) p-Methoxyaniline 
D) p-Trifluoromethylaniline 
E) p-Chloroaniline 
A) Aniline 
B) p-Trimethylammonium aniline 
C) p-Methoxyaniline 
D) p-Trifluoromethylaniline 
E) p-Chloroaniline

Question 2

What would be the product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 3

What would be the product of the following reaction sequence?

Accepted Answer

A) p-bromobenzamide 
B) p-bromobenzaldehyde oxime 
C) p-bromobenzenesulfonamide 
D) p-bromoaniline 
E) 4-bromo-3-chlorobenzoic acid 
A) p-bromobenzamide 
B) p-bromobenzaldehyde oxime 
C) p-bromobenzenesulfonamide 
D) p-bromoaniline 
E) 4-bromo-3-chlorobenzoic acid

Question 4

Outline the steps involved in the Gabriel synthesis of allylamine.

Accepted Answer

The answer of Outline the steps involved in the Gabriel...

Question 5

What final product is likely when cyclohexene is subjected to the following reaction sequence? Give structural details of all significant intermediates.
i)H3O+,H2O; ii)PCC; iii)(CH3)2NH; iv)NaBH3CN

Accepted Answer

Question 6

Explain why cyclohexylamine is a stronger base than aniline.

Accepted Answer

There are two major reasons for the obse

Question 7

Outline the steps involved in the synthesis of 3-chloro-4-fluoroacetophenone from 4-aminoacetophenone.

Accepted Answer

i)Cl₂,FeCl₃;

Question 8

Which of the following compounds would be the strongest base?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 9

The aromatic amine purine contains how many nitrogen atoms?

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
E) 5 
A) 1 
B) 2 
C) 3 
D) 4 
E) 5

Question 10

What is the chief alkene product when butylethylmethylpropylammonium hydroxide is heated to 150S1U1P1$\circ$S1S1P0C?

Accepted Answer

A) CH2=CH2 
B) CH3CH=CH2 
C) CH3CH2CH=CH2 
D) (
E) -CH3CH=CHCH3 
E) (Z)-CH3CH=CHCH3 
A) CH2=CH2 
B) CH3CH=CH2 
C) CH3CH2CH=CH2 
D) (
E) -CH3CH=CHCH3 
E) (Z)-CH3CH=CHCH3

Question 11

What would be the reactant in the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 12

What would be the product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 13

Amines are known to rapidly undergo pyramidal inversion at ordinary temperatures,preventing the resolution of enantiomeric forms when the amine is a chirality center.The proposed transition state of the inversion process is shown below.Using an orbital diagram,illustrate the hybridization at nitrogen for this proposed transition state.

Accepted Answer

In the trigonal pyramidal form,nitrogen

Question 14

Consider the synthesis below.What is reagent A?

Accepted Answer

A) Br2,FeBr3 
B) Fe,HCl; then OH- 
C) NH2Cl,AlCl3 
D) H3PO2 
E) LiNH2 
A) Br2,FeBr3 
B) Fe,HCl; then OH- 
C) NH2Cl,AlCl3 
D) H3PO2 
E) LiNH2

Question 15

What type of amine is pyrrolidine?

Accepted Answer

A) Primary 
B) Secondary 
C) Tertiary 
D) Quaternary 
E) None of these choices. 
A) Primary 
B) Secondary 
C) Tertiary 
D) Quaternary 
E) None of these choices.

Question 16

Before modern spectroscopic methods were developed,structures of many complex amines were elucidated by examining the products obtained during Hofmann elimination of their quaternary ammonium hydroxides.The typical procedure involved the following steps,repeated as necessary,depending on whether the amine was primary,secondary or tertiary,until the final product was nitrogen-free: i)CH3I (excess); ii)Ag2O,H2O; iii)heat.What product(s)is (are)likely to be formed if 3,4-dimethylpiperidine is subjected to the above procedure?

Accepted Answer

The reaction sequence would need to be r

Question 17

What compound is likely to be obtained via the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 18

What would be the product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 19

Which is the major product of the following reaction?   2

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 20

Which of the following can be used to prepare 2-aminopentane (pure)?

Accepted Answer

A) I 
B) II 
C) III 
D) I and II 
E) II and III 
A) I 
B) II 
C) III 
D) I and II 
E) II and III

Exam 20: Amines

Which of the following aryl amines is the strongest base?

What would be the product of the following reaction sequence?

What would be the product of the following reaction sequence?

Outline the steps involved in the Gabriel synthesis of allylamine.

What final product is likely when cyclohexene is subjected to the following reaction sequence? Give structural details of all significant intermediates. i)H3O+,H2O; ii)PCC; iii)(CH3)2NH; iv)NaBH3CN

Explain why cyclohexylamine is a stronger base than aniline.

Outline the steps involved in the synthesis of 3-chloro-4-fluoroacetophenone from 4-aminoacetophenone.

Which of the following compounds would be the strongest base?

The aromatic amine purine contains how many nitrogen atoms?

What is the chief alkene product when butylethylmethylpropylammonium hydroxide is heated to 150 ∘\circ∘ C?

What would be the reactant in the following reaction sequence?

What would be the product of the following reaction sequence?

Consider the synthesis below.What is reagent A?

What type of amine is pyrrolidine?

What compound is likely to be obtained via the following reaction sequence?

What would be the product of the following reaction sequence?

Which is the major product of the following reaction? 2

Which of the following can be used to prepare 2-aminopentane (pure)?

The Basics

Families of Carbon

Acids and Bases

Nomenclature and Conformations of Alkanes and Cycloalkanes

Stereochemistry

Nucleophilic Reactions

Alkenes and Alkynes I

Alkenes and Alkynes II

Nuclear Magnetic Resonance and Mass Spectrometry

Radical Reactions

Alcohols and Ethers

Alcohols From Carbonyl Compounds

Conjugated Unsaturated Systems

Aromatic Compounds

Reactions of Aromatic Compounds

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Reactions at the Α Carbon of Carbonyl Compounds

Condensation and Conjugate Addition Reactions of Carbonyl Compounds

Transition Metal Complexes

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids and Protein Synthesis

Filters

What final product is likely when cyclohexene is subjected to the following reaction sequence? Give structural details of all significant intermediates. i)H₃O⁺,H₂O; ii)PCC; iii)(CH₃)₂NH; iv)NaBH₃CN

What is the chief alkene product when butylethylmethylpropylammonium hydroxide is heated to 150^$\circ$C?