Question 1

While primary amines react with nitrous acid to generate diazonium salts,secondary amines react with nitrous acid to produce ___.

Accepted Answer

The answer of While primary amines react with nitrous acid...

Question 2

Which of these would be predicted to have the smallest pKa?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 3

What is the final product?

Accepted Answer

A) 2-Bromo-4-methylaniline 
B) 2,6-Dibromo-4-methylaniline 
C) 2,6-Dibromo-4-methylphenol 
D) 2,4-Dibromophenol 
E) 3,5-Dibromotoluene 
A) 2-Bromo-4-methylaniline 
B) 2,6-Dibromo-4-methylaniline 
C) 2,6-Dibromo-4-methylphenol 
D) 2,4-Dibromophenol 
E) 3,5-Dibromotoluene

Question 4

Which is the best method to prepare   ?

Accepted Answer

A)    
B) 
  
C) 
  
D) 
  
E) 
  
A)    
B) 
  
C) 
  
D) 
  
E)

Question 5

What would be the product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 6

Explain how an enantiomerically pure amine can be used to resolve racemic forms of acidic compounds.

Accepted Answer

The amine reacts with the acid

Question 7

What final product is likely when cyclohexene is subjected to the following reaction sequence? Give structural details of all significant intermediates.
i)H3O+,H2O; ii)PCC; iii)piperidine; iv)NaBH3CN

Accepted Answer

Question 8

Which combination of reactants will not produce   ?

Accepted Answer

A) 
  
B) 
  
C) 
  
D) 
  
E) 
  
A) 
  
B) 
  
C) 
  
D) 
  
E)

Question 9

What is the chief product of the Hofmann elimination reaction applied to the compound shown?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 10

In solution,two factors affect the relative basicity of amines.These factors are: ___.

Accepted Answer

electron donation by alkyl sub

Question 11

How would one carry out the following transformation?

Accepted Answer

A) NaNO2,HCl,0-5 S1U1P1$\circ$S1S1P0C; then HNO3 
B) NaNO2,HCl,0-5 S1U1P1$\circ$S1S1P0C; then H3PO2 
C) NaNO2,HCl,0-5 S1U1P1$\circ$S1S1P0C; then H2,Ni 
D) C6H5SO2Cl,OH-; then HCl 
E) NaH,DMSO 
A) NaNO2,HCl,0-5 S1U1P1$\circ$S1S1P0C; then HNO3 
B) NaNO2,HCl,0-5 S1U1P1$\circ$S1S1P0C; then H3PO2 
C) NaNO2,HCl,0-5 S1U1P1$\circ$S1S1P0C; then H2,Ni 
D) C6H5SO2Cl,OH-; then HCl 
E) NaH,DMSO

Question 12

This type of compound is the only one of these which can be converted by reduction into a 1S1U1P1$\circ$S1S1P0,2S1U1P1$\circ$S1S1P0 or 3S1U1P1$\circ$S1S1P0 amine,according to its particular structure:

Accepted Answer

A) Nitrile 
B) Oxime 
C) Azide 
D) Amide 
E) Nitroalkane 
A) Nitrile 
B) Oxime 
C) Azide 
D) Amide 
E) Nitroalkane

Question 13

What would be the product of the following reaction sequence?

Accepted Answer

A) p-bromobenzamide 
B) p-bromobenzaldehyde oxime 
C) p-bromobenzenesulfonamide 
D) p-bromoaniline 
E) 4-bromo-3-chlorobenzoic acid 
A) p-bromobenzamide 
B) p-bromobenzaldehyde oxime 
C) p-bromobenzenesulfonamide 
D) p-bromoaniline 
E) 4-bromo-3-chlorobenzoic acid

Question 14

Arrange the following compounds in order of increasing basicity (least to most)in aqueous solution:

Accepted Answer

A) IV < II < I < III 
B) III < II < IV < I 
C) II < I < III < IV 
D) II < III < I < IV 
E) Cannot be determined from information given 
A) IV < II < I < III 
B) III < II < IV < I 
C) II < I < III < IV 
D) II < III < I < IV 
E) Cannot be determined from information given

Question 15

What would be the product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 16

What would be the product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 17

What would be the product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 18

Consider the synthesis below.What is reagent "Z"?

Accepted Answer

A) CuCl 
B) CuCl2 
C) NaCl 
D) KCl 
E) HCl/heat 
A) CuCl 
B) CuCl2 
C) NaCl 
D) KCl 
E) HCl/heat

Question 19

What is the product of the following reaction sequence:

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 20

Which of the following bases has a conjugate acid with the largest pKa?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Exam 20: Amines

While primary amines react with nitrous acid to generate diazonium salts,secondary amines react with nitrous acid to produce ___.

Which of these would be predicted to have the smallest pKa?

What is the final product?

Which is the best method to prepare ?

What would be the product of the following reaction sequence?

Explain how an enantiomerically pure amine can be used to resolve racemic forms of acidic compounds.

What final product is likely when cyclohexene is subjected to the following reaction sequence? Give structural details of all significant intermediates. i)H3O+,H2O; ii)PCC; iii)piperidine; iv)NaBH3CN

Which combination of reactants will not produce ?

What is the chief product of the Hofmann elimination reaction applied to the compound shown?

In solution,two factors affect the relative basicity of amines.These factors are: ___.

How would one carry out the following transformation?

This type of compound is the only one of these which can be converted by reduction into a 1 ∘\circ∘ ,2 ∘\circ∘ or 3 ∘\circ∘ amine,according to its particular structure:

What would be the product of the following reaction sequence?

Arrange the following compounds in order of increasing basicity (least to most)in aqueous solution:

What would be the product of the following reaction sequence?

What would be the product of the following reaction?

What would be the product of the following reaction sequence?

Consider the synthesis below.What is reagent "Z"?

What is the product of the following reaction sequence:

Which of the following bases has a conjugate acid with the largest pKa?

The Basics

Families of Carbon

Acids and Bases

Nomenclature and Conformations of Alkanes and Cycloalkanes

Stereochemistry

Nucleophilic Reactions

Alkenes and Alkynes I

Alkenes and Alkynes II

Nuclear Magnetic Resonance and Mass Spectrometry

Radical Reactions

Alcohols and Ethers

Alcohols From Carbonyl Compounds

Conjugated Unsaturated Systems

Aromatic Compounds

Reactions of Aromatic Compounds

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Reactions at the Α Carbon of Carbonyl Compounds

Condensation and Conjugate Addition Reactions of Carbonyl Compounds

Transition Metal Complexes

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids and Protein Synthesis

Filters

Which of these would be predicted to have the smallest pK_a?

What final product is likely when cyclohexene is subjected to the following reaction sequence? Give structural details of all significant intermediates. i)H₃O⁺,H₂O; ii)PCC; iii)piperidine; iv)NaBH₃CN

This type of compound is the only one of these which can be converted by reduction into a 1^$\circ$,2^$\circ$ or 3^$\circ$ amine,according to its particular structure:

Which of the following bases has a conjugate acid with the largest pK_a?