Exam 31: Special Topic: Cancer

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A(n) ________ is an abnormal mass of tissue that is surrounded by a capsule of connective tissue and usually remains at the site where it forms.

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benign tumor

Certain new cancer therapies deal with the inhibition of angiogenesis (formation of blood vessels). How would inhibition of blood vessel formation be beneficial in terms of treating cancer?

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Blocking blood vessel formation to a tumor ultimately starves the tumor and blocks routes by which malignant cells can enter the bloodstream and travel to other sites.

Describe the cancer stem cell hypothesis. How might this explain the inability of traditional cancer treatments such as radiation and chemotherapy to completely eradicate tumors?

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The cancer stem cell hypothesis suggests that only certain cells in a tumor are capable of continual cell division and initiating the growth of new tumors. Traditional cancer therapies have focused on killing the rapidly dividing cancer cells (progenitor cells) but may not target cancer stem cells. Thus, although death of progenitor cells would shrink the tumor, cancer stem cells could replenish the population, causing the tumor to return.

Dietary choices that can increase the risk of certain cancers include ________.

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An adult patient has just received a diagnosis of brain cancer and is undergoing treatment. Based on what you know about cell division and cancer, why does this seem unusual?

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In order to be successful, chemotherapy drugs have to stop cell division. The most likely method for this would be to ________.

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How does chemotherapy work as a treatment for cancer? Why is it not always effective?

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This chapter discussed six different ways to treat cancer. List at least five, and briefly explain each process.

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Cells can activate a genetic suicide program in response to a signal in the body. This programmed cell death is called ________.

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The risk of cancer can be reduced by ________.

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An allele known as BRCA1 is often found in women with breast and ovarian cancer. However, some women develop these cancers and do not have the BRCA1 allele. In addition, some women who have BRCA1 never develop breast or ovarian cancer. How can this be explained?

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Which of the following is not a characteristic of cancerous cells?

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An oncologist (a physician who specializes in cancer) compares two biopsy samples by looking at the percentage of cells in mitosis. Sample 1 has 15% of cells in mitosis, and sample 2 has 8% of cells in mitosis. These samples are of the same tissue type. Which sample is likely to be cancerous, and why? Why is it important that the two samples being compared came from the same tissue type?

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Which of the following cancers is often not detected in women until a late stage because of a lack of routine diagnostic testing?

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If a person had cancer that had already metastasized by the time of diagnosis, the treatment options at this point would most likely include ________.

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Which type of cancer had the largest percentage of deaths among women in 2012?

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Explain why malignant tumors are more dangerous than benign tumors.

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Which statement concerning cell division and cancer is incorrect?

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Which of the following is a typical means of halting normal cell division?

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The removal and analysis of a piece of tissue that is suspected to be cancerous is called a(n) ________.

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