Question 1

The disease process of myasthenia gravis produces muscle weakness by

Accepted Answer

A)  overproducing ACh receptors on muscles. 
B)  reducing ACh function in the basal forebrain. 
C)  reducing the number of ACh receptors on muscles. 
D)  reducing ACh function in the dorsolateral pons. 
E)  enhancing the release of glycine onto spinal cord motoneurons. 
A)  overproducing ACh receptors on muscles. 
B)  reducing ACh function in the basal forebrain. 
C)  reducing the number of ACh receptors on muscles. 
D)  reducing ACh function in the dorsolateral pons. 
E)  enhancing the release of glycine onto spinal cord motoneurons.

Question 2

Which pair below represents the receptor subtypes for acetylcholine?

Accepted Answer

A)  cholinergic; adrenergic 
B)  muscarinic; adrenergic 
C)  alpha-cholinergic; beta-cholinergic 
D)  nicotinic; muscarinic 
E)  beta-cholinergic; delta-cholinergic 
A)  cholinergic; adrenergic 
B)  muscarinic; adrenergic 
C)  alpha-cholinergic; beta-cholinergic 
D)  nicotinic; muscarinic 
E)  beta-cholinergic; delta-cholinergic

Question 3

The major excitatory neurotransmitter in the brain is a(n) ____________ called _______________.

Accepted Answer

A)  amino acid; acetylcholine 
B)  amino acid; glutamate 
C)  monamine; serotonin 
D)  monoamine; dopamine 
E)  amino acid; dopamine 
A)  amino acid; acetylcholine 
B)  amino acid; glutamate 
C)  monamine; serotonin 
D)  monoamine; dopamine 
E)  amino acid; dopamine

Question 4

Where a drug acts in the cell would be a

Accepted Answer

A)  site of action. 
B)  drug effect. 
C)  exogenous substance. 
D)  endogenous substance. 
E)  drug. 
A)  site of action. 
B)  drug effect. 
C)  exogenous substance. 
D)  endogenous substance. 
E)  drug.

Question 5

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

Accepted Answer

A)  Pharmacotherapy 
B)  Pharmacokinetics 
C)  Drug metabolism 
D)  Pharmacodynamics 
E)  Neurobotany 
A)  Pharmacotherapy 
B)  Pharmacokinetics 
C)  Drug metabolism 
D)  Pharmacodynamics 
E)  Neurobotany

Question 6

A drug that binds with a postsynaptic receptor, but does not open ion channels, would be termed a(n)

Accepted Answer

A)  direct agonist. 
B)  ligand. 
C)  direct synergist. 
D)  direct antagonist. 
E)  indirect antagonist 
A)  direct agonist. 
B)  ligand. 
C)  direct synergist. 
D)  direct antagonist. 
E)  indirect antagonist

Question 7

Cell bodies of serotonin neurons are located within the

Accepted Answer

A)  substantia nigra. 
B)  basal forebrain. 
C)  ventral tegmental area. 
D)  spinal cord. 
E)  raphe nuclei. 
A)  substantia nigra. 
B)  basal forebrain. 
C)  ventral tegmental area. 
D)  spinal cord. 
E)  raphe nuclei.

Question 8

The drug reserpine

Accepted Answer

A)  was used medically to treat high blood pressure. 
B)  is used to treat myasthenia gravis. 
C)  blocks the storage of monoamines in vesicles. 
D)  can produce Parkinson's disease in some persons. 
E)  interferes with the synthesis of dopamine. 
A)  was used medically to treat high blood pressure. 
B)  is used to treat myasthenia gravis. 
C)  blocks the storage of monoamines in vesicles. 
D)  can produce Parkinson's disease in some persons. 
E)  interferes with the synthesis of dopamine.

Question 9

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Accepted Answer

A)  intraperitoneal 
B)  oral 
C)  intravascular 
D)  topical 
E)  intranasal 
A)  intraperitoneal 
B)  oral 
C)  intravascular 
D)  topical 
E)  intranasal

Question 10

Drugs that block the reuptake of serotonin or that cause the release of serotonin are used therapeutically to treat

Accepted Answer

A)  anorexia nervosa. 
B)  depression. 
C)  mania. 
D)  psychosis. 
E)  bipolar disorder. 
A)  anorexia nervosa. 
B)  depression. 
C)  mania. 
D)  psychosis. 
E)  bipolar disorder.

Question 11

Which pair of drugs below is known to facilitate and inhibit (respectively) the release of acetylcholine?

Accepted Answer

A)  fluoxetine; nicotine 
B)  botulinum toxin; muscarine 
C)  botulinum toxin; black widow spider venom 
D)  black widow spider venom; botulinum toxin 
E)  black widow spider venom; fluoxetine 
A)  fluoxetine; nicotine 
B)  botulinum toxin; muscarine 
C)  botulinum toxin; black widow spider venom 
D)  black widow spider venom; botulinum toxin 
E)  black widow spider venom; fluoxetine

Question 12

Alcohol withdrawal can lead to seizures because of the effect of alcohol on

Accepted Answer

A)  blocking AMPA receptors. 
B)  stimulating 5-HT receptors. 
C)  displacing magnesium ions from the GABA receptors. 
D)  blocking NMDA receptors. 
E)  blocking 5-HT receptors. 
A)  blocking AMPA receptors. 
B)  stimulating 5-HT receptors. 
C)  displacing magnesium ions from the GABA receptors. 
D)  blocking NMDA receptors. 
E)  blocking 5-HT receptors.

Question 13

Damage to the ________ cholinergic system would be expected to impair learning.

Accepted Answer

A)  dorsolateral pons 
B)  hypothalamocortical 
C)  basal forebrain 
D)  medial septal 
E)  corticospinal 
A)  dorsolateral pons 
B)  hypothalamocortical 
C)  basal forebrain 
D)  medial septal 
E)  corticospinal

Question 14

________ demonstrate the effect of a particular dose until the maximum effect is reached.

Accepted Answer

Dose respo

Question 15

Damage to the ________ dopaminergic system would be expected to impair movement.

Accepted Answer

A)  nigrostriatal 
B)  hypothalamocortical 
C)  mesocortical 
D)  mesolimbic 
E)  corticospinal 
A)  nigrostriatal 
B)  hypothalamocortical 
C)  mesocortical 
D)  mesolimbic 
E)  corticospinal

Question 16

Describe the biosynthesis of acetylcholine. List three different means that would act to alter the release of acetylcholine.

Accepted Answer

ACh is formed from choline and acetyl-co

Question 17

Hemicholnium-3 blocks the choline transporter, preventing recycling of choline. This drug is a(n)

Accepted Answer

A)  agonist. 
B)  promotor. 
C)  villain. 
D)  antagonist. 
E)  precursor. 
A)  agonist. 
B)  promotor. 
C)  villain. 
D)  antagonist. 
E)  precursor.

Question 18

Serotonin is synthesized from

Accepted Answer

A)  tyrosine. 
B)  tyramine. 
C)  tryptophan. 
D)  blood platelets. 
E)  glutamate. 
A)  tyrosine. 
B)  tyramine. 
C)  tryptophan. 
D)  blood platelets. 
E)  glutamate.

Question 19

Degeneration of neurons within the ________ dopamine system leads to Parkinson's disease.

Accepted Answer

A)  nigrostriatal 
B)  mesocortical 
C)  hypothalamocortical 
D)  mesolimbic 
E)  retinal-suprachiasmatic 
A)  nigrostriatal 
B)  mesocortical 
C)  hypothalamocortical 
D)  mesolimbic 
E)  retinal-suprachiasmatic

Question 20

Glutamate, GABA, and glycine are important because these are

Accepted Answer

A)  the major excitatory neurotransmitters in the CNS. 
B)  known to be solely inhibitory in the brain. 
C)  the predominant neuromodulators in the spinal cord. 
D)  the most common neurotransmitters in the CNS. 
E)  involved in Parkinson's disease. 
A)  the major excitatory neurotransmitters in the CNS. 
B)  known to be solely inhibitory in the brain. 
C)  the predominant neuromodulators in the spinal cord. 
D)  the most common neurotransmitters in the CNS. 
E)  involved in Parkinson's disease.

The disease process of myasthenia gravis produces muscle weakness by

Which pair below represents the receptor subtypes for acetylcholine?

The major excitatory neurotransmitter in the brain is a(n) called ___.

Where a drug acts in the cell would be a

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

A drug that binds with a postsynaptic receptor, but does not open ion channels, would be termed a(n)

Cell bodies of serotonin neurons are located within the

The drug reserpine

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Drugs that block the reuptake of serotonin or that cause the release of serotonin are used therapeutically to treat

Which pair of drugs below is known to facilitate and inhibit (respectively) the release of acetylcholine?

Alcohol withdrawal can lead to seizures because of the effect of alcohol on

Damage to the ________ cholinergic system would be expected to impair learning.

________ demonstrate the effect of a particular dose until the maximum effect is reached.

Damage to the ________ dopaminergic system would be expected to impair movement.

Describe the biosynthesis of acetylcholine. List three different means that would act to alter the release of acetylcholine.

Hemicholnium-3 blocks the choline transporter, preventing recycling of choline. This drug is a(n)

Serotonin is synthesized from

Degeneration of neurons within the ________ dopamine system leads to Parkinson's disease.

Glutamate, GABA, and glycine are important because these are

Introduction

Structure and Function of Cells of the Nervous System

Structure of the Nervous System

Methods and Strategies of Research

Vision

Audition, the Body Senses, and the Chemical Senses

Control of Movement

Sleep and Biological Rhythms

Reproductive Behavior

Emotion

Ingestive Behavior

Learning and Memory

Human Communication

Neurological Disorders

Schizophrenia and the Affective Disorders

Anxiety Disorders, Autistic Disorder, attention-Deficithyperactivity Disorder, and Stress Disorders

Substance Abuse

Filters

Exam 4: Psychopharmacology

The disease process of myasthenia gravis produces muscle weakness by

Which pair below represents the receptor subtypes for acetylcholine?

The major excitatory neurotransmitter in the brain is a(n) ____________ called _______________.

Where a drug acts in the cell would be a

________ refers to the process by which drugs are absorbed, distributed within the body, metabolized, and then excreted from the body.

A drug that binds with a postsynaptic receptor, but does not open ion channels, would be termed a(n)

Cell bodies of serotonin neurons are located within the

The drug reserpine

The ________ route of drug administration is commonly used for small laboratory animals such as the rat.

Drugs that block the reuptake of serotonin or that cause the release of serotonin are used therapeutically to treat

Which pair of drugs below is known to facilitate and inhibit (respectively) the release of acetylcholine?

Alcohol withdrawal can lead to seizures because of the effect of alcohol on

Damage to the ________ cholinergic system would be expected to impair learning.

________ demonstrate the effect of a particular dose until the maximum effect is reached.

Damage to the ________ dopaminergic system would be expected to impair movement.

Describe the biosynthesis of acetylcholine. List three different means that would act to alter the release of acetylcholine.

Hemicholnium-3 blocks the choline transporter, preventing recycling of choline. This drug is a(n)

Serotonin is synthesized from

Degeneration of neurons within the ________ dopamine system leads to Parkinson's disease.

Glutamate, GABA, and glycine are important because these are

Introduction

Structure and Function of Cells of the Nervous System

Structure of the Nervous System

Methods and Strategies of Research

Vision

Audition, the Body Senses, and the Chemical Senses

Control of Movement

Sleep and Biological Rhythms

Reproductive Behavior

Emotion

Ingestive Behavior

Learning and Memory

Human Communication

Neurological Disorders

Schizophrenia and the Affective Disorders

Anxiety Disorders, Autistic Disorder, attention-Deficithyperactivity Disorder, and Stress Disorders

Substance Abuse

Filters

The major excitatory neurotransmitter in the brain is a(n) called ___.