Question 1

Predict the major product for the following reaction sequence.

Accepted Answer

The answer of Predict the major product for the following...

Question 2

Predict the product for the following reaction sequence.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 3

Which of the following compounds would NOT undergo racemization in the presence of a base?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  II and III 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  II and III

Question 4

Predict the product(s) for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  all of these 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  all of these

Question 5

Provide the structure of reactant (X) for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 6

Which of the following bases will completely convert 1,4-cyclohexanedione into an enolate?

Accepted Answer

A)  sodium hydroxide 
B)  sodium ethoxide 
C)  LDA 
D)  sodium hydride 
E)  both C and D 
A)  sodium hydroxide 
B)  sodium ethoxide 
C)  LDA 
D)  sodium hydride 
E)  both C and D

Question 7

Provide the reactants that would give the following aldol condensation product.

Accepted Answer

The answer of Provide the reactants that would give the...

Question 8

Which one of the following compounds can be prepared using the Michael reaction?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  none of these 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  none of these

Question 9

Which one of the following reaction sequences will yield 2,2-dimethylcyclohexane-1,3-dione.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  II and IV 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  II and IV

Question 10

Provide the reactant(s) that would give the following possible aldol condensation product.

Accepted Answer

The answer of Provide the reactant(s) that would give the...

Question 11

Provide the reagents necessary to carry out the following conversion using a malonic ester synthesis.

Accepted Answer

1. NaOCH₂CH₃ 2. (CH₃)₂CH

Question 12

Predict the major product(s) for the following reaction.

Accepted Answer

A)  I 
B)  II and IV 
C)  III 
D)  I and III 
E)  V 
A)  I 
B)  II and IV 
C)  III 
D)  I and III 
E)  V

Question 13

Which of the following compounds can be prepared using the Dieckmann condensation?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  II and IV 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  II and IV

Question 14

Predict the product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 15

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. H₃O⁺/heat

Question 16

Provide the reactants that will yield the following compound as a crossed Claisen condensation product.

Accepted Answer

The answer of Provide the reactants that will yield the...

Question 17

Provide the reactants that would give the following aldol condensation product.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  none of these 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  none of these

Question 18

Predict the major product for the following reaction.

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
E)  V 
A)  I 
B)  II 
C)  III 
D)  IV 
E)  V

Question 19

Which one of the following compounds is most acidic?

Accepted Answer

A)  ethyl acetoacetate 
B)  2-butanone 
C)  ethyl pentanoate 
D)  1-butanol 
E)  3-pentanone 
A)  ethyl acetoacetate 
B)  2-butanone 
C)  ethyl pentanoate 
D)  1-butanol 
E)  3-pentanone

Question 20

Provide the reagents necessary to carry out the following conversion.

Accepted Answer

1. NaOH/I₂

Exam 21: Alpha Carbon Chemistry: Enols and Enolates

Predict the major product for the following reaction sequence.

Predict the product for the following reaction sequence.

Which of the following compounds would NOT undergo racemization in the presence of a base?

Predict the product(s) for the following reaction.

Provide the structure of reactant (X) for the following reaction.

Which of the following bases will completely convert 1,4-cyclohexanedione into an enolate?

Provide the reactants that would give the following aldol condensation product.

Which one of the following compounds can be prepared using the Michael reaction?

Which one of the following reaction sequences will yield 2,2-dimethylcyclohexane-1,3-dione.

Provide the reactant(s) that would give the following possible aldol condensation product.

Provide the reagents necessary to carry out the following conversion using a malonic ester synthesis.

Predict the major product(s) for the following reaction.

Which of the following compounds can be prepared using the Dieckmann condensation?

Predict the product for the following reaction.

Provide the reagents necessary to carry out the following conversion.

Provide the reactants that will yield the following compound as a crossed Claisen condensation product.

Provide the reactants that would give the following aldol condensation product.

Predict the major product for the following reaction.

Which one of the following compounds is most acidic?

Provide the reagents necessary to carry out the following conversion.

A Review of General Chemistry: Electrons, Bonds, and Molecular Properties

Molecular Representations

Acids and Bases

Alkanes and Cycloalkanes

Stereoisomerism

Chemical Reactivity and Mechanisms

Alkyl Halides: Nucleophilic Substitution and Elimination Reactions

Addition Reactions of Alkenes

Alkynes

Radical Reactions

Synthesis

Alcohols and Phenols

Ethers and Epoxides; Thiols and Sulfides

Infrared Spectroscopy and Mass Spectrometry

Nuclear Magnetic Resonance Spectroscopy

Conjugated Pi Systems and Pericyclic Reactions

Aromatic Compounds

Aromatic Substitution Reactions

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Amines

Introduction to Organometallic Compounds

Carbohydrates

Amino Acids, Peptides, and Proteins

Lipids

Synthetic Polymers

Filters