Exam 19: Biomolecules: Amino Acids,peptides,and Proteins

Consider the following structure.Based on this structure answer the following question(s). -Refer to instructions.Identify the C-terminal amino acid and the N-terminal amino acid.

Write the equation for the reaction,using methanol (CH₃OH),that would render the carboxyl group of alanine unreactive.

Which of the following amino acids has an aromatic side chain?

Which of the following tripeptides is not hydrolysed by chymotrypsin?

Which of the following reagents can be used to cleave a tert-butoxycarbonyl (Boc)protecting group from a peptide?

Draw the structure of the product of the following reaction and describe the usefulness of this type of reaction.

To what structural feature does the term "secondary structure" refer?

Match a structure from the list below to each of the following terms. -

Refer to the data below to answer the following question. -Refer to instructions.At what pH would you carry out an electrophoresis experiment if you wanted to separate a mixture of lysine,aspartic acid and phenylalanine? Explain.

Which of the following tripeptides is not hydrolysed by trypsin?

Refer to the data below to answer the following question(s). Porcine dynorphin is a neuropeptide having 17 amino acid residues.Its structure is shown below. Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln -Refer to instructions.Show the steps involved in a synthesis of F-G-I using the Merrifield procedure.

To what structural feature does the term "primary structure" refer?

Which of the following dipeptides is L-Ser-L-Phe?

Instructions: Match a term from the list below to each definition.

How does phenyl isothiocyanate,Ph-N=C=S,react with a peptide in the Edman degradation?

Which of the following amino acids migrates to the positive electrode on paper electrophoresis at a pH of 7.0?