Question 1

Which is the main cellular mediator released during degranulation of mast cells is associated with capillary dilation (capillaries become more permeable)

Accepted Answer

A) Interleukins 
B) Histamine 
C) Antihistamine 
D) IgG 
A) Interleukins 
B) Histamine 
C) Antihistamine 
D) IgG

Question 2

Type IV hypersensitivity involves _____.

Accepted Answer

A) B cells 
B) complement 
C) immune complexes 
D) TH1 cells 
A) B cells 
B) complement 
C) immune complexes 
D) TH1 cells

Question 3

Which of the following is an example of lower respiratory anaphylaxis

Accepted Answer

A) Tuberculosis 
B) Legionnaire's disease 
C) Hay fever 
D) Asthma 
A) Tuberculosis 
B) Legionnaire's disease 
C) Hay fever 
D) Asthma

Question 4

Drug reactions:

Accepted Answer

A) are associated with only 3 of the 4 types of hypersensitivities 
B) are common because most drug molecules are large enough to act as allergens 
C) can occur with antibiotics 
D) two of these 
A) are associated with only 3 of the 4 types of hypersensitivities 
B) are common because most drug molecules are large enough to act as allergens 
C) can occur with antibiotics 
D) two of these

Question 5

Immunodeficiency refers to the immune system responding _____.

Accepted Answer

A) in an exaggerated way to a foreign substance 
B) so that there is too much of a good thing 
C) inadequately to an antigen 
D) to its own tissues as if they were foreign 
A) in an exaggerated way to a foreign substance 
B) so that there is too much of a good thing 
C) inadequately to an antigen 
D) to its own tissues as if they were foreign

Question 6

All of the following are associated with Type IV hypersensitivity except:

Accepted Answer

A) antigen presenting cells 
B) plasma cells 
C) sensitized TH1 cells 
D) granulomatous lesions 
A) antigen presenting cells 
B) plasma cells 
C) sensitized TH1 cells 
D) granulomatous lesions

Question 7

In an effort to have a successful tissue transplant,the _____ of the recipient and the donor are matched.

Accepted Answer

A) IgD antibodies 
B) Seroantigens 
C) Human leukocyte antigens 
D) two of these 
A) IgD antibodies 
B) Seroantigens 
C) Human leukocyte antigens 
D) two of these

Question 8

Examples of autoimmune diseases include which of the following

Accepted Answer

A) Systemic lupus erythematosus 
B) Myasthenia gravis 
C) Rheumatoid arthritis 
D) All of these 
A) Systemic lupus erythematosus 
B) Myasthenia gravis 
C) Rheumatoid arthritis 
D) All of these

Question 9

Which of the following statements about localized anaphylaxis is incorrect

Accepted Answer

A) "atopy" means "out of place" 
B) demonstrates a wheal and flare 
C) if the allergen enters the skin,may result in itching 
D) is most likely life threatening 
A) "atopy" means "out of place" 
B) demonstrates a wheal and flare 
C) if the allergen enters the skin,may result in itching 
D) is most likely life threatening

Question 10

The match between HLAs determines the suitability of transplants,which HLA is known to generate the strongest transplant rejection reaction

Accepted Answer

A) HLA-A and HLA-B 
B) HLA B27 
C) HLA Dw3 
D) HLA-DR 
A) HLA-A and HLA-B 
B) HLA B27 
C) HLA Dw3 
D) HLA-DR

Question 11

Which of the following definitions of tissue transplants is incorrect

Accepted Answer

A) Autograft - tissue is moved from one part of the body to another 
B) Allograft - tissue is grafted between two individuals who are not genetically identical 
C) Xenograft - tissue is grafted from one animal species to another 
D) Isograft - tissue is grafted from parent to child 
A) Autograft - tissue is moved from one part of the body to another 
B) Allograft - tissue is grafted between two individuals who are not genetically identical 
C) Xenograft - tissue is grafted from one animal species to another 
D) Isograft - tissue is grafted from parent to child

Question 12

Type II hypersensitivities appear to be responsible for the tissue damage in all of the following EXCEPT:

Accepted Answer

A) rheumatic fever following strep throat infections 
B) transfusion reactions 
C) hemolytic disease of the newborn 
D) lupus erythematosus 
A) rheumatic fever following strep throat infections 
B) transfusion reactions 
C) hemolytic disease of the newborn 
D) lupus erythematosus

Question 13

Which of the following statements related to serum sickness is false

Accepted Answer

A) Serum sickness was initially associated with injections of anti-toxin for diphtheria. 
B) The patient's immune system makes antibody against horse proteins. 
C) Glomerulus function is impaired due to immune complexes. 
D) Most patients die rather quickly from the condition. 
A) Serum sickness was initially associated with injections of anti-toxin for diphtheria. 
B) The patient's immune system makes antibody against horse proteins. 
C) Glomerulus function is impaired due to immune complexes. 
D) Most patients die rather quickly from the condition.

Question 14

Rheumatoid arthritis:

Accepted Answer

A) involves autoantibodies that are against the acetylcholine receptors 
B) form IgM:IgG immune complexes and TH1 cells which initiate inflammation in joints 
C) mainly affects the joints of the hands and the joints 
D) two of these 
A) involves autoantibodies that are against the acetylcholine receptors 
B) form IgM:IgG immune complexes and TH1 cells which initiate inflammation in joints 
C) mainly affects the joints of the hands and the joints 
D) two of these

Question 15

Autoimmunization:

Accepted Answer

A) is an acquired process not linked to any genetic factors 
B) involves vaccinations that are administered by the patient not a doctor 
C) is the process by which hypersensitivity to self develops 
D) two of these 
A) is an acquired process not linked to any genetic factors 
B) involves vaccinations that are administered by the patient not a doctor 
C) is the process by which hypersensitivity to self develops 
D) two of these

Question 16

Cytotoxic hypersensitivity is mediated by _____.

Accepted Answer

A) IgG,IgM 
B) IgE 
C) complement 
D) two of these 
A) IgG,IgM 
B) IgE 
C) complement 
D) two of these

Question 17

Hypersensitivity or allergy refers to the immune system responding _____.

Accepted Answer

A) in an exaggerated way to a foreign substance 
B) too little too late 
C) inadequately to an antigen 
D) to its own tissues as if they were foreign 
A) in an exaggerated way to a foreign substance 
B) too little too late 
C) inadequately to an antigen 
D) to its own tissues as if they were foreign

Question 18

Immediate type hypersensitivity is mediated by _____.

Accepted Answer

A) IgG 
B) T cells 
C) IgM 
D) IgE 
A) IgG 
B) T cells 
C) IgM 
D) IgE

Question 19

Antigenic or molecular mimicry _____.

Accepted Answer

A) occurs when T cells attack tissue antigens similar to bacterial antigens 
B) involves self reactive T cells hiding in the thymus 
C) leads to an increase in the number of regulatory T cells 
D) none of these 
A) occurs when T cells attack tissue antigens similar to bacterial antigens 
B) involves self reactive T cells hiding in the thymus 
C) leads to an increase in the number of regulatory T cells 
D) none of these

Question 20

Secondary immunodeficiency diseases can be caused by all of the following except:

Accepted Answer

A) Hodgkin's disease 
B) radiation 
C) genetic defects 
D) tuberculosis 
A) Hodgkin's disease 
B) radiation 
C) genetic defects 
D) tuberculosis

Exam 19: Immune Disorders

Which is the main cellular mediator released during degranulation of mast cells is associated with capillary dilation (capillaries become more permeable)

Type IV hypersensitivity involves _____.

Which of the following is an example of lower respiratory anaphylaxis

Drug reactions:

Immunodeficiency refers to the immune system responding _____.

All of the following are associated with Type IV hypersensitivity except:

In an effort to have a successful tissue transplant,the _____ of the recipient and the donor are matched.

Examples of autoimmune diseases include which of the following

Which of the following statements about localized anaphylaxis is incorrect

The match between HLAs determines the suitability of transplants,which HLA is known to generate the strongest transplant rejection reaction

Which of the following definitions of tissue transplants is incorrect

Type II hypersensitivities appear to be responsible for the tissue damage in all of the following EXCEPT:

Which of the following statements related to serum sickness is false

Rheumatoid arthritis:

Autoimmunization:

Cytotoxic hypersensitivity is mediated by _____.

Hypersensitivity or allergy refers to the immune system responding _____.

Immediate type hypersensitivity is mediated by _____.

Antigenic or molecular mimicry _____.

Secondary immunodeficiency diseases can be caused by all of the following except:

Scope and History of Microbiology

The Microbiome

Fundamentals of Chemistry

Microscopy and Staining

Characteristics of Prokaryotic and Eukaryotic Cells

Essential Concepts of Metabolism

Growth and Culturing of Bacteria

Microbial Genetics

Gene Transfer and Genetic Engineering

An Introduction to Taxonomy: The Bacteria

Viruses

Eukaryotic Microorganisms and Parasites

Sterilization and Disinfection

Antimicrobial Therapy

Host-Microbe Relationships and Disease Processes

Epidemiology and Nosocomial Infections

Innate Host Defenses

Basic Principles of Adaptive Immunity and Immunization

Diseases of the Skin and Eyes; Wounds and Bites

Urogenital and Sexually Transmitted Diseases

Diseases of the Respiratory System

Oral and Gastrointestinal Diseases

Cardiovascular, Lymphatic, and Systemic Diseases

Diseases of the Nervous System

Environmental Microbiology

Applied Microbiology

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