Question 1

Any chemical substance used in medical practice is known as a/an:

Accepted Answer

A) antibiotic 
B) antimicrobial agent 
C) semi-synthetic drug 
D) chemotherapeutic agent 
A) antibiotic 
B) antimicrobial agent 
C) semi-synthetic drug 
D) chemotherapeutic agent

Question 2

The sulfonamide antibiotics kill bacteria by _____.

Accepted Answer

A) interfering with cell wall synthesis 
B) disrupting folic acid metabolism 
C) reacting with bacterial cell membranes 
D) inhibiting bacterial motility 
A) interfering with cell wall synthesis 
B) disrupting folic acid metabolism 
C) reacting with bacterial cell membranes 
D) inhibiting bacterial motility

Question 3

Mechanisms of bacterial resistance to antimicrobial agents include all of the following except:

Accepted Answer

A) alteration of ribosomes 
B) alteration of an enzyme 
C) development of enzymes 
D) alteration of normal microflora 
A) alteration of ribosomes 
B) alteration of an enzyme 
C) development of enzymes 
D) alteration of normal microflora

Question 4

Interferons and immunoenhancers:

Accepted Answer

A) are widely used to treat viruses 
B) cause no side effects 
C) include levamisole and inosiplex 
D) have been thoroughly researched 
A) are widely used to treat viruses 
B) cause no side effects 
C) include levamisole and inosiplex 
D) have been thoroughly researched

Question 5

Clear area on agar that surrounds a filter paper disk on the disk diffusion tests and represents inhibited growth of a test microorganism is called:

Accepted Answer

A) minimum inhibitory concentration 
B) minimum bactericidal concentration 
C) zone of inhibition 
D) serum killing power 
A) minimum inhibitory concentration 
B) minimum bactericidal concentration 
C) zone of inhibition 
D) serum killing power

Question 6

Rifampin:

Accepted Answer

A) inhibits RNA synthesis 
B) inhibits all nucleic acid synthesis 
C) disrupts of cell membrane function 
D) acts as an antimetabolite 
A) inhibits RNA synthesis 
B) inhibits all nucleic acid synthesis 
C) disrupts of cell membrane function 
D) acts as an antimetabolite

Question 7

Metronidazole:

Accepted Answer

A) is effective against viruses 
B) has no side effects 
C) prevents overgrowth of Candida yeast infections 
D) is useful in the treatment of amoebas and Giardia 
A) is effective against viruses 
B) has no side effects 
C) prevents overgrowth of Candida yeast infections 
D) is useful in the treatment of amoebas and Giardia

Question 8

Characteristics of an ideal antimicrobial agent include all of the following except:

Accepted Answer

A) resistance by microorganisms 
B) reasonable cost 
C) long shelf life 
D) toxicity not easily altered 
A) resistance by microorganisms 
B) reasonable cost 
C) long shelf life 
D) toxicity not easily altered

Question 9

Paul Ehrlich:

Accepted Answer

A) coined the term chemotherapy 
B) discovered salvarsan in 1910 
C) discovered the antibiotic streptomycin 
D) accomplished two of these 
A) coined the term chemotherapy 
B) discovered salvarsan in 1910 
C) discovered the antibiotic streptomycin 
D) accomplished two of these

Question 10

Which of the following directly pertain to inhibition of cellular protein synthesis by antimicrobial agents

Accepted Answer

A) cellular cytoplasm is lost 
B) binding and inhibition of RNA polymerase 
C) imitation or molecular mimicry of normal molecules 
D) interferes with accurate translation of mRNA message 
A) cellular cytoplasm is lost 
B) binding and inhibition of RNA polymerase 
C) imitation or molecular mimicry of normal molecules 
D) interferes with accurate translation of mRNA message

Question 11

Which of the following antibiotics is an inhibitor of DNA gyrase

Accepted Answer

A) Ethambutol 
B) Ciprofloxacin 
C) Tobramycin 
D) Neomycin 
A) Ethambutol 
B) Ciprofloxacin 
C) Tobramycin 
D) Neomycin

Question 12

Which one of the following pairs is incorrectly matched with antibiotic and its target

Accepted Answer

A) penicillin; gram positive bacteria 
B) nystatin; fungi 
C) tetracycline; viruses 
D) griseofulvin; fungi 
A) penicillin; gram positive bacteria 
B) nystatin; fungi 
C) tetracycline; viruses 
D) griseofulvin; fungi

Question 13

Determining microbial sensitivity to an antimicrobial agent by using a filter paper soaked with the drug on a bacterial lawn on an agar plate is called:

Accepted Answer

A) the dilution method 
B) the disk diffusion method 
C) automated testing 
D) phage typing 
A) the dilution method 
B) the disk diffusion method 
C) automated testing 
D) phage typing

Question 14

Chloramphenicol,a bacteriostatic antimicrobial agent,is an inhibitor of:

Accepted Answer

A) nucleic acid synthesis 
B) cell wall synthesis 
C) cell membrane function 
D) protein synthesis 
A) nucleic acid synthesis 
B) cell wall synthesis 
C) cell membrane function 
D) protein synthesis

Question 15

Because the tetracyclines are effective against a large variety of different organisms,they are considered to:

Accepted Answer

A) be narrow-spectrum drugs 
B) have a therapeutic dosage level 
C) be bacteriocidal 
D) be broad-spectrum drugs 
A) be narrow-spectrum drugs 
B) have a therapeutic dosage level 
C) be bacteriocidal 
D) be broad-spectrum drugs

Question 16

Why are resistant organisms found often in hospitalized patients

Accepted Answer

A) Stringent efforts maintain sanitary conditions. 
B) Many infections in patients are being treated with different antibiotics. 
C) Doctors are treating outpatients with multiple antibiotics. 
D) Two of these. 
A) Stringent efforts maintain sanitary conditions. 
B) Many infections in patients are being treated with different antibiotics. 
C) Doctors are treating outpatients with multiple antibiotics. 
D) Two of these.

Question 17

Purine or pyrimidine analogs:

Accepted Answer

A) act as antimetabolites 
B) inhibit ribosome function 
C) disrupt cell membrane function 
D) inhibit nucleic acid synthesis 
A) act as antimetabolites 
B) inhibit ribosome function 
C) disrupt cell membrane function 
D) inhibit nucleic acid synthesis

Question 18

The mode of action of penicillin is:

Accepted Answer

A) inhibition of cell wall synthesis 
B) disruption of cell membranes 
C) inhibition of protein synthesis 
D) inhibition of nucleic acid synthesis 
A) inhibition of cell wall synthesis 
B) disruption of cell membranes 
C) inhibition of protein synthesis 
D) inhibition of nucleic acid synthesis

Question 19

Which of following is NOT a way to limit the ability of microorganisms to acquire drug resistance

Accepted Answer

A) High levels of antimicrobial agent in the patient 
B) Inhibiting growth of invading microbes so immune defenses can kill them 
C) Taking antibiotics until the patient feels better 
D) Taking two antibiotics synergistically 
A) High levels of antimicrobial agent in the patient 
B) Inhibiting growth of invading microbes so immune defenses can kill them 
C) Taking antibiotics until the patient feels better 
D) Taking two antibiotics synergistically

Question 20

Which of the following is NOT considered a mode of action by antimicrobial agents

Accepted Answer

A) Inhibition of protein synthesis. 
B) Inhibition of cell wall synthesis. 
C) Inhibition of membrane permeability. 
D) Disruption of selective toxicity. 
A) Inhibition of protein synthesis. 
B) Inhibition of cell wall synthesis. 
C) Inhibition of membrane permeability. 
D) Disruption of selective toxicity.

Exam 14: Antimicrobial Therapy

Any chemical substance used in medical practice is known as a/an:

The sulfonamide antibiotics kill bacteria by _____.

Mechanisms of bacterial resistance to antimicrobial agents include all of the following except:

Interferons and immunoenhancers:

Clear area on agar that surrounds a filter paper disk on the disk diffusion tests and represents inhibited growth of a test microorganism is called:

Rifampin:

Metronidazole:

Characteristics of an ideal antimicrobial agent include all of the following except:

Paul Ehrlich:

Which of the following directly pertain to inhibition of cellular protein synthesis by antimicrobial agents

Which of the following antibiotics is an inhibitor of DNA gyrase

Which one of the following pairs is incorrectly matched with antibiotic and its target

Determining microbial sensitivity to an antimicrobial agent by using a filter paper soaked with the drug on a bacterial lawn on an agar plate is called:

Chloramphenicol,a bacteriostatic antimicrobial agent,is an inhibitor of:

Because the tetracyclines are effective against a large variety of different organisms,they are considered to:

Why are resistant organisms found often in hospitalized patients

Purine or pyrimidine analogs:

The mode of action of penicillin is:

Which of following is NOT a way to limit the ability of microorganisms to acquire drug resistance

Which of the following is NOT considered a mode of action by antimicrobial agents

Scope and History of Microbiology

The Microbiome

Fundamentals of Chemistry

Microscopy and Staining

Characteristics of Prokaryotic and Eukaryotic Cells

Essential Concepts of Metabolism

Growth and Culturing of Bacteria

Microbial Genetics

Gene Transfer and Genetic Engineering

An Introduction to Taxonomy: The Bacteria

Viruses

Eukaryotic Microorganisms and Parasites

Sterilization and Disinfection

Host-Microbe Relationships and Disease Processes

Epidemiology and Nosocomial Infections

Innate Host Defenses

Basic Principles of Adaptive Immunity and Immunization

Immune Disorders

Diseases of the Skin and Eyes; Wounds and Bites

Urogenital and Sexually Transmitted Diseases

Diseases of the Respiratory System

Oral and Gastrointestinal Diseases

Cardiovascular, Lymphatic, and Systemic Diseases

Diseases of the Nervous System

Environmental Microbiology

Applied Microbiology

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