Question 1

Rh immune globulin should be given within how many hours following delivery?

Accepted Answer

A) 12 
B) 24 
C) 48 
D) 72 
A) 12 
B) 24 
C) 48 
D) 72 D

Question 2

In a suspected case of HDFN,what significant information can be obtained from the baby's blood smear?

Accepted Answer

A) The estimated platelet count 
B) Increase in nucleated red cells 
C) The presences of spherocytes 
D) Increase in monocytes 
A) The estimated platelet count 
B) Increase in nucleated red cells 
C) The presences of spherocytes 
D) Increase in monocytes C

Question 3

The rosette test will detect a fetomaternal hemorrhage as small as:

Accepted Answer

A) 5 mL. 
B) 10 mL. 
C) 15 mL. 
D) 20 mL. 
A) 5 mL. 
B) 10 mL. 
C) 15 mL. 
D) 20 mL. B

Question 4

All of the following are goals of an exchange transfusion except to:

Accepted Answer

A) correct anemia. 
B) remove high levels of unconjugated bilirubin. 
C) remove high levels of maternal antibody. 
D) restore the platelet count. 
A) correct anemia. 
B) remove high levels of unconjugated bilirubin. 
C) remove high levels of maternal antibody. 
D) restore the platelet count.

Question 5

To identify the cause of suspected hemolytic disease of the fetus and newborn,which tests are performed?

Accepted Answer

A) ABO group 
B) D testing 
C) Direct antiglobulin test 
D) All of the above 
A) ABO group 
B) D testing 
C) Direct antiglobulin test 
D) All of the above

Question 6

Select the situation where the administration of Rh immune globulin would be contraindicated.

Accepted Answer

D
Rh immune globulin

Question 7

Anti-D in the serum of a third-trimester pregnant woman with a titer of 16 is indicative of:

Accepted Answer

A) the presence of Rh immune globulin administered at 28 weeks. 
B) active immunization. 
C) passive immunization. 
D) none of the above. 
A) the presence of Rh immune globulin administered at 28 weeks. 
B) active immunization. 
C) passive immunization. 
D) none of the above.

Question 8

A weakly reactive anti-D was detected in a sample from a D-negative mother one day following delivery of a D-negative baby.Based on these results the lab should:

Accepted Answer

A) titer the anti-D. 
B) perform a rosette test. 
C) review records for prenatal RhIG administration. 
D) administer RhIG. 
A) titer the anti-D. 
B) perform a rosette test. 
C) review records for prenatal RhIG administration. 
D) administer RhIG.

Question 9

A large fetomaternal bleed in a D-negative woman who delivered a D-positive infant should be suspected if the:

Accepted Answer

A) direct antiglobulin test on the infant is positive. 
B) infant is premature. 
C) fetomaternal hemorrhage screen result is positive. 
D) maternal antibody screen is positive postpartum. 
A) direct antiglobulin test on the infant is positive. 
B) infant is premature. 
C) fetomaternal hemorrhage screen result is positive. 
D) maternal antibody screen is positive postpartum.

Question 10

A group O,D-positive mother gave birth to an A-negative infant.After 24 hours,the newborn's bilirubin level rose to 19 mg/dL.A direct antiglobulin test performed on the cord blood specimen was positive with anti-IgG.What is the most probable antibody causing this?

Accepted Answer

A) Anti-D 
B) Anti-A 
C) Anti-B 
D) Anti-A,B 
A) Anti-D 
B) Anti-A 
C) Anti-B 
D) Anti-A,B

Question 11

What immunoglobulin is capable of crossing the placenta?

Accepted Answer

A) IgA 
B) IgG 
C) IgM 
D) IgE 
A) IgA 
B) IgG 
C) IgM 
D) IgE

Question 12

All of the following are common characteristics of ABO hemolytic disease of the fetus and newborn except:

Accepted Answer

A) weak positive direct antiglobulin test. 
B) mother is group A. 
C) the antibody on the infant's cells is anti-A,B. 
D) mild clinical symptoms. 
A) weak positive direct antiglobulin test. 
B) mother is group A. 
C) the antibody on the infant's cells is anti-A,B. 
D) mild clinical symptoms.

Question 13

To be considered a candidate for Rh immune globulin,the mother is __________ and the infant is __________.

Accepted Answer

A) D-positive,D-negative 
B) D-negative,D-positive 
C) D-negative,D-negative 
D) D-positive,D-positive 
A) D-positive,D-negative 
B) D-negative,D-positive 
C) D-negative,D-negative 
D) D-positive,D-positive

Question 14

In testing amniotic fluid,the Liley method of predicting the severity of hemolytic disease of the fetus and newborn is based on:

Accepted Answer

A) colorimetric protein analysis. 
B) optical density of bilirubin at 450 nm. 
C) ratio of lecithin to sphingomyelin. 
D) titration of antibody. 
A) colorimetric protein analysis. 
B) optical density of bilirubin at 450 nm. 
C) ratio of lecithin to sphingomyelin. 
D) titration of antibody.

Question 15

Which of the following is true regarding the rosette test?

Accepted Answer

A) It is a staining procedure that differentiates fetal and adult cells. 
B) The test is valid only if the mother is D-negative and the infant is D-positive. 
C) Indicator cells bind to the D-positive maternal cells forming a rosette. 
D) The test is a quantitative test to determine how many vials of Rh immune globulin to administer. 
A) It is a staining procedure that differentiates fetal and adult cells. 
B) The test is valid only if the mother is D-negative and the infant is D-positive. 
C) Indicator cells bind to the D-positive maternal cells forming a rosette. 
D) The test is a quantitative test to determine how many vials of Rh immune globulin to administer.

Question 16

A 300-$\mu$g dose of Rh immune globulin contains sufficient anti-D to protect against how much whole blood?

Accepted Answer

A) 25 mL 
B) 30 mL 
C) 50 mL 
D) 100 mL 
A) 25 mL 
B) 30 mL 
C) 50 mL 
D) 100 mL

Question 17

Rh immune globulin contains:

Accepted Answer

A) IgG anti-D. 
B) immune serum globulin. 
C) IgM anti-D. 
D) gamma globulin. 
A) IgG anti-D. 
B) immune serum globulin. 
C) IgM anti-D. 
D) gamma globulin.

Question 18

Select the true statement regarding ABO hemolytic disease of the fetus and newborn.

Accepted Answer

A) It is frequently seen in group A mothers with group O infants. 
B) It cannot occur during prima gravida (first pregnancy). 
C) Bilirubin levels often exceed 15 mg/dL in the affected infants. 
D) The frequency of ABO hemolytic disease of the fetus and newborn is greater than Rh hemolytic disease of the fetus and newborn. 
A) It is frequently seen in group A mothers with group O infants. 
B) It cannot occur during prima gravida (first pregnancy). 
C) Bilirubin levels often exceed 15 mg/dL in the affected infants. 
D) The frequency of ABO hemolytic disease of the fetus and newborn is greater than Rh hemolytic disease of the fetus and newborn.

Question 19

A newborn phenotypes as group O,D-positive with a 1+ direct antiglobulin test.The mother's antibody screening test is negative.Assuming the antibody screen is valid,one should consider the reason for the positive DAT is due to an antibody against __________ antigen.

Accepted Answer

A) D 
B) A or B 
C) low-incidence 
D) high-incidence 
A) D 
B) A or B 
C) low-incidence 
D) high-incidence

Question 20

Which of the following antibodies have not been known to cause hemolytic disease of the fetus and newborn?

Accepted Answer

A) Anti-C 
B) Anti-K 
C) Anti-Lea 
D) Anti-S 
A) Anti-C 
B) Anti-K 
C) Anti-Lea 
D) Anti-S

Rh immune globulin should be given within how many hours following delivery?

In a suspected case of HDFN,what significant information can be obtained from the baby's blood smear?

The rosette test will detect a fetomaternal hemorrhage as small as:

All of the following are goals of an exchange transfusion except to:

To identify the cause of suspected hemolytic disease of the fetus and newborn,which tests are performed?

Select the situation where the administration of Rh immune globulin would be contraindicated.

Anti-D in the serum of a third-trimester pregnant woman with a titer of 16 is indicative of:

A weakly reactive anti-D was detected in a sample from a D-negative mother one day following delivery of a D-negative baby.Based on these results the lab should:

A large fetomaternal bleed in a D-negative woman who delivered a D-positive infant should be suspected if the:

A group O,D-positive mother gave birth to an A-negative infant.After 24 hours,the newborn's bilirubin level rose to 19 mg/dL.A direct antiglobulin test performed on the cord blood specimen was positive with anti-IgG.What is the most probable antibody causing this?

What immunoglobulin is capable of crossing the placenta?

All of the following are common characteristics of ABO hemolytic disease of the fetus and newborn except:

To be considered a candidate for Rh immune globulin,the mother is and the infant is .

In testing amniotic fluid,the Liley method of predicting the severity of hemolytic disease of the fetus and newborn is based on:

Which of the following is true regarding the rosette test?

A 300- $\mu$ g dose of Rh immune globulin contains sufficient anti-D to protect against how much whole blood?

Rh immune globulin contains:

Select the true statement regarding ABO hemolytic disease of the fetus and newborn.

A newborn phenotypes as group O,D-positive with a 1+ direct antiglobulin test.The mother's antibody screening test is negative.Assuming the antibody screen is valid,one should consider the reason for the positive DAT is due to an antibody against __________ antigen.

Which of the following antibodies have not been known to cause hemolytic disease of the fetus and newborn?

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Filters

Exam 11: Hemolytic Disease of the Fetus and Newborn

Rh immune globulin should be given within how many hours following delivery?

In a suspected case of HDFN,what significant information can be obtained from the baby's blood smear?

The rosette test will detect a fetomaternal hemorrhage as small as:

All of the following are goals of an exchange transfusion except to:

To identify the cause of suspected hemolytic disease of the fetus and newborn,which tests are performed?

Select the situation where the administration of Rh immune globulin would be contraindicated.

Anti-D in the serum of a third-trimester pregnant woman with a titer of 16 is indicative of:

A weakly reactive anti-D was detected in a sample from a D-negative mother one day following delivery of a D-negative baby.Based on these results the lab should:

A large fetomaternal bleed in a D-negative woman who delivered a D-positive infant should be suspected if the:

A group O,D-positive mother gave birth to an A-negative infant.After 24 hours,the newborn's bilirubin level rose to 19 mg/dL.A direct antiglobulin test performed on the cord blood specimen was positive with anti-IgG.What is the most probable antibody causing this?

What immunoglobulin is capable of crossing the placenta?

All of the following are common characteristics of ABO hemolytic disease of the fetus and newborn except:

To be considered a candidate for Rh immune globulin,the mother is __________ and the infant is __________.

In testing amniotic fluid,the Liley method of predicting the severity of hemolytic disease of the fetus and newborn is based on:

Which of the following is true regarding the rosette test?

A 300- μ\muμ g dose of Rh immune globulin contains sufficient anti-D to protect against how much whole blood?

Rh immune globulin contains:

Select the true statement regarding ABO hemolytic disease of the fetus and newborn.

A newborn phenotypes as group O,D-positive with a 1+ direct antiglobulin test.The mother's antibody screening test is negative.Assuming the antibody screen is valid,one should consider the reason for the positive DAT is due to an antibody against __________ antigen.

Which of the following antibodies have not been known to cause hemolytic disease of the fetus and newborn?

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Filters

To be considered a candidate for Rh immune globulin,the mother is and the infant is .

A 300- $\mu$ g dose of Rh immune globulin contains sufficient anti-D to protect against how much whole blood?