Question 1

Lewis system antibodies have not been implicated in hemolytic disease of the fetus and newborn because:

Accepted Answer

A) the antigens are not fully developed at birth. 
B) Lewis system antibodies do not cross the placenta. 
C) the antibodies are not clinically significant. 
D) all of the above are correct. 
A) the antigens are not fully developed at birth. 
B) Lewis system antibodies do not cross the placenta. 
C) the antibodies are not clinically significant. 
D) all of the above are correct. D

Question 2

Antibodies to which of the following blood group system show dosage (i.e. ,are stronger with homozygous expression of the antigen)?

Accepted Answer

A) Lutheran 
B) P 
C) Duffy 
D) Kell 
A) Lutheran 
B) P 
C) Duffy 
D) Kell C

Question 3

Match each characteristic with the appropriate blood group system.A selection may be used more than once.
-Antibodies in this system often fall below detectable levels and are associated with delayed transfusion reactions

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy C

Question 4

Antibodies to Kidd,Kell,and Duffy blood group antigens share all the following characteristics except:

Accepted Answer

A) can cause hemolytic disease of the newborn. 
B) usually detected only by the indirect antiglobulin test. 
C) enhanced with enzyme treatment. 
D) can cause transfusion reactions. 
A) can cause hemolytic disease of the newborn. 
B) usually detected only by the indirect antiglobulin test. 
C) enhanced with enzyme treatment. 
D) can cause transfusion reactions.

Question 5

Red cells that phenotype as S-s- are also:

Accepted Answer

A) M-negative. 
B) N-negative. 
C) Tja-negative. 
D) U-negative. 
A) M-negative. 
B) N-negative. 
C) Tja-negative. 
D) U-negative.

Question 6

Match each characteristic with the appropriate blood group system.A selection may be used more than once.
-Antibody to this antigen demonstrates weak mixed field reaction

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy

Question 7

Match each characteristic with the appropriate blood group system.A selection may be used more than once.
-System associated with McLeod phenotype

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy

Question 8

If all red cells tested at room temperature are positive with a patient's serum except for cord cells,the probable antibody identity is:

Accepted Answer

A) anti-Lu. 
B) anti-Lea. 
C) anti-I. 
D) anti-M. 
A) anti-Lu. 
B) anti-Lea. 
C) anti-I. 
D) anti-M.

Question 9

Match each characteristic with the appropriate blood group system.A selection may be used more than once.
-System associated with resistance to malaria

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy

Question 10

Match each characteristic with the appropriate blood group system.A selection may be used more than once.
-Antigen has a higher frequency in females

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy

Question 11

Which condition is often associated with the presence of anti-I?

Accepted Answer

A) Infectious mononucleosis 
B) Mycoplasma pneumoniae infection 
C) Pregnancy 
D) Colon cancer 
A) Infectious mononucleosis 
B) Mycoplasma pneumoniae infection 
C) Pregnancy 
D) Colon cancer

Question 12

An antibody to Jsb was identified in a patient scheduled for elective surgery at a later date.What is the best approach to finding compatible blood?

Accepted Answer

A) Contact the rare donor registry since Jsb negative units are rare. 
B) Request that family members be tested to determine if they share the same phenotype. 
C) Screen donors from the black population since being Jsb negative is common in blacks. 
D) A and B are correct. 
A) Contact the rare donor registry since Jsb negative units are rare. 
B) Request that family members be tested to determine if they share the same phenotype. 
C) Screen donors from the black population since being Jsb negative is common in blacks. 
D) A and B are correct.

Question 13

Which of the following phenotypes is heterozygous?

Accepted Answer

A) Fy(a-b+) 
B) Jk(a+b-) 
C) Fy(a+b+) 
D) Le(a+b-) 
A) Fy(a-b+) 
B) Jk(a+b-) 
C) Fy(a+b+) 
D) Le(a+b-)

Question 14

The Donath-Landsteiner antibody is:

Accepted Answer

A) an IgG auto anti-P. 
B) an IgM auto anti-I. 
C) anti-IH that reacts at cold temperatures. 
D) IgG anti-pk. 
A) an IgG auto anti-P. 
B) an IgM auto anti-I. 
C) anti-IH that reacts at cold temperatures. 
D) IgG anti-pk.

Question 15

K1-positive donor red cells were mistakenly transfused to a recipient with anti-K.The patient's posttransfusion blood sample has a positive direct antiglobulin test with polyspecific antihuman globulin.The direct antiglobulin test is positive because anti-K is an __________ antibody that has sensitized the __________ cells in vivo.

Accepted Answer

A) IgG,donor's 
B) IgM,donor's 
C) IgG,recipient's 
D) IgM,recipient's 
A) IgG,donor's 
B) IgM,donor's 
C) IgG,recipient's 
D) IgM,recipient's

Question 16

Antigens of the P system are structurally related to which of the following blood group systems?

Accepted Answer

A) MNS 
B) ABH 
C) Kell 
D) Duffy 
A) MNS 
B) ABH 
C) Kell 
D) Duffy

Question 17

Which of the following facts is not a characteristic of Kell system antibodies?

Accepted Answer

A) Usually clinically significant IgG antibodies 
B) Best detected in indirect antiglobulin test phases 
C) Lose reactivity with proteolytic enzyme reagents 
D) Do not bind complement proteins 
A) Usually clinically significant IgG antibodies 
B) Best detected in indirect antiglobulin test phases 
C) Lose reactivity with proteolytic enzyme reagents 
D) Do not bind complement proteins

Question 18

A patient's antibody history listed an anti-cellano.This antigen is also known as:

Accepted Answer

A) c in the Rh system. 
B) k in the Kell system. 
C) Cs in the Cost system. 
D) SC in the Scianna system. 
A) c in the Rh system. 
B) k in the Kell system. 
C) Cs in the Cost system. 
D) SC in the Scianna system.

Question 19

All the following statements are true regarding Lewis system antibodies except antibodies:

Accepted Answer

A) may be observed at the immediate spin,37° C,and antihuman globulin phases. 
B) can be neutralized by Lewis substance. 
C) may cause hemolysis in vitro. 
D) do not react following enzyme treatment of cells. 
A) may be observed at the immediate spin,37° C,and antihuman globulin phases. 
B) can be neutralized by Lewis substance. 
C) may cause hemolysis in vitro. 
D) do not react following enzyme treatment of cells.

Question 20

Match each characteristic with the appropriate blood group system.A selection may be used more than once.
-Antibodies are sensitive to enzymes and have high-titer low-avidity characteristics

Accepted Answer

A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy 
A) Cartwright 
B) MNSs 
C) Kidd 
D) Vel 
E) Xga
F)Sda antigen
G)Chido/Rodgers
H)Kell
I)Duffy

Lewis system antibodies have not been implicated in hemolytic disease of the fetus and newborn because:

Antibodies to which of the following blood group system show dosage (i.e. ,are stronger with homozygous expression of the antigen)?

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antibodies in this system often fall below detectable levels and are associated with delayed transfusion reactions

Antibodies to Kidd,Kell,and Duffy blood group antigens share all the following characteristics except:

Red cells that phenotype as S-s- are also:

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antibody to this antigen demonstrates weak mixed field reaction

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -System associated with McLeod phenotype

If all red cells tested at room temperature are positive with a patient's serum except for cord cells,the probable antibody identity is:

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -System associated with resistance to malaria

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antigen has a higher frequency in females

Which condition is often associated with the presence of anti-I?

An antibody to Js^b was identified in a patient scheduled for elective surgery at a later date.What is the best approach to finding compatible blood?

Which of the following phenotypes is heterozygous?

The Donath-Landsteiner antibody is:

Antigens of the P system are structurally related to which of the following blood group systems?

Which of the following facts is not a characteristic of Kell system antibodies?

A patient's antibody history listed an anti-cellano.This antigen is also known as:

All the following statements are true regarding Lewis system antibodies except antibodies:

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antibodies are sensitive to enzymes and have high-titer low-avidity characteristics

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Filters

Exam 6: Other Blood Group Systems

Lewis system antibodies have not been implicated in hemolytic disease of the fetus and newborn because:

Antibodies to which of the following blood group system show dosage (i.e. ,are stronger with homozygous expression of the antigen)?

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antibodies in this system often fall below detectable levels and are associated with delayed transfusion reactions

Antibodies to Kidd,Kell,and Duffy blood group antigens share all the following characteristics except:

Red cells that phenotype as S-s- are also:

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antibody to this antigen demonstrates weak mixed field reaction

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -System associated with McLeod phenotype

If all red cells tested at room temperature are positive with a patient's serum except for cord cells,the probable antibody identity is:

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -System associated with resistance to malaria

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antigen has a higher frequency in females

Which condition is often associated with the presence of anti-I?

An antibody to Jsb was identified in a patient scheduled for elective surgery at a later date.What is the best approach to finding compatible blood?

Which of the following phenotypes is heterozygous?

The Donath-Landsteiner antibody is:

Antigens of the P system are structurally related to which of the following blood group systems?

Which of the following facts is not a characteristic of Kell system antibodies?

A patient's antibody history listed an anti-cellano.This antigen is also known as:

All the following statements are true regarding Lewis system antibodies except antibodies:

Match each characteristic with the appropriate blood group system.A selection may be used more than once. -Antibodies are sensitive to enzymes and have high-titer low-avidity characteristics

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Rh Blood Group System

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Filters

An antibody to Js^b was identified in a patient scheduled for elective surgery at a later date.What is the best approach to finding compatible blood?