Question 1

The weak D test detects:

Accepted Answer

A) the Du antigen. 
B) the missing D mosaic. 
C) a weak D antibody. 
D) a weak D antigen. 
A) the Du antigen. 
B) the missing D mosaic. 
C) a weak D antibody. 
D) a weak D antigen. D

Question 2

Match the Fisher-Race notation with the correct Weiner notation for the following:
-ry

Accepted Answer

A) Ce 
B) CE 
C) DCE 
D) Dce 
A) Ce 
B) CE 
C) DCE 
D) Dce B

Question 3

A patient phenotypes as D+C+E-c-e+.The most likely genotype is:

Accepted Answer

A) R1r. 
B) R1R1. 
C) R1r'. 
D) R1R0. 
A) R1r. 
B) R1R1. 
C) R1r'. 
D) R1R0. B

Question 4

Why is the determination of the D antigen important for women during pregnancy?

Accepted Answer

A) A D-positive mother can form anti-D during pregnancy that may destroy the D-positive red cells of the fetus. 
B) A D-negative mother should be given Rh immune globulin to prevent potential formation of anti-D during delivery of a D-positive infant. 
C) A D-negative mother may form anti-D if the father of the child is also D-negative. 
D) A D-positive mother may pass her red cells to the D-negative fetus and cause hemolytic disease of the fetus and newborn. 
A) A D-positive mother can form anti-D during pregnancy that may destroy the D-positive red cells of the fetus. 
B) A D-negative mother should be given Rh immune globulin to prevent potential formation of anti-D during delivery of a D-positive infant. 
C) A D-negative mother may form anti-D if the father of the child is also D-negative. 
D) A D-positive mother may pass her red cells to the D-negative fetus and cause hemolytic disease of the fetus and newborn.

Question 5

Match the Fisher-Race notation with the correct Weiner notation for the following:
-r'

Accepted Answer

A) Ce 
B) CE 
C) DCE 
D) Dce 
A) Ce 
B) CE 
C) DCE 
D) Dce

Question 6

The LW antigen expression is typically stronger on __________ cells.

Accepted Answer

A) D-positive red 
B) D-negative red 
C) Rh null 
D) D-variant 
A) D-positive red 
B) D-negative red 
C) Rh null 
D) D-variant

Question 7

If a D-positive person appears to have anti-D in their serum,the most likely explanation is:

Accepted Answer

A) D-deletion phenotype. 
B) compound antigen. 
C) partial D antigen. 
D) transposition effect. 
A) D-deletion phenotype. 
B) compound antigen. 
C) partial D antigen. 
D) transposition effect.

Question 8

Match the Fisher-Race notation with the correct Weiner notation for the following:
-R0

Accepted Answer

A) Ce 
B) CE 
C) DCE 
D) Dce 
A) Ce 
B) CE 
C) DCE 
D) Dce

Question 9

The frequency of the D-negative phenotype in the population is:

Accepted Answer

A) 15%. 
B) 85%. 
C) 50%. 
D) 35%. 
A) 15%. 
B) 85%. 
C) 50%. 
D) 35%.

Question 10

How would a donor who tested negative with anti-D reagent in the immediate spin test but tested positive at antihuman globulin with anti-D reagent be labeled?

Accepted Answer

A) D-positive 
B) D-negative 
A) D-positive 
B) D-negative

Question 11

The inheritance of the Rh antigens are:

Accepted Answer

A) X-linked recessive. 
B) X-linked dominant. 
C) autosomal recessive. 
D) codominant. 
A) X-linked recessive. 
B) X-linked dominant. 
C) autosomal recessive. 
D) codominant.

Question 12

All of the following can cause the D antigen expression to be weaker except:

Accepted Answer

A) inheriting the G gene. 
B) inheriting the C antigen in trans to the D antigen. 
C) an RHD gene that is genetically weaker. 
D) partial D expression. 
A) inheriting the G gene. 
B) inheriting the C antigen in trans to the D antigen. 
C) an RHD gene that is genetically weaker. 
D) partial D expression.

Question 13

Match the following phenotypes with the most probable genotype in the Weiner nomenclature.
-DcE

Accepted Answer

A) R1r 
B) R1R1 
C) R2R2 
D) rr 
A) R1r 
B) R1R1 
C) R2R2 
D) rr

Question 14

How is it genetically possible for a child to phenotype as D-negative?

Accepted Answer

A) Both parents are heterozygous D-positive. 
B) Both parents are homozygous D-positive. 
C) Mom is homozygous D-positive,and Dad is heterozygous D-positive. 
D) The sibling is D-positive. 
A) Both parents are heterozygous D-positive. 
B) Both parents are homozygous D-positive. 
C) Mom is homozygous D-positive,and Dad is heterozygous D-positive. 
D) The sibling is D-positive.

Question 15

Most Rh system antibodies are of which immunoglobulin class?

Accepted Answer

A) IgM 
B) IgG 
C) IgA 
D) IgE 
A) IgM 
B) IgG 
C) IgA 
D) IgE

Question 16

Current theory regarding the genetics of the Rh system suggests that:

Accepted Answer

A) each Rh system antigen is coded by its own gene locus. 
B) Rh system antigens are coded by two closely linked genes. 
C) one gene locus with multiple alleles codes for the protein antigens. 
D) the Rh system genes are a haplotype that codes for three sets of alleles. 
A) each Rh system antigen is coded by its own gene locus. 
B) Rh system antigens are coded by two closely linked genes. 
C) one gene locus with multiple alleles codes for the protein antigens. 
D) the Rh system genes are a haplotype that codes for three sets of alleles.

Question 17

Which of the following phenotypes will react with anti-f?

Accepted Answer

A) rr 
B) R1R1 
C) R2R2 
D) R1R2 
A) rr 
B) R1R1 
C) R2R2 
D) R1R2

Question 18

The numeric Rh4 nomenclature refers to which antigen in the Rosenfield notation?

Accepted Answer

A) C 
B) c 
C) e 
D) E 
A) C 
B) c 
C) e 
D) E

Question 19

Testing for the weak D expression is performed by:

Accepted Answer

A) using anti-Du antisera with an extended incubation. 
B) using monoclonal anti-D. 
C) performing the indirect antiglobulin test with anti-D. 
D) performing the direct antiglobulin test with anti-D. 
A) using anti-Du antisera with an extended incubation. 
B) using monoclonal anti-D. 
C) performing the indirect antiglobulin test with anti-D. 
D) performing the direct antiglobulin test with anti-D.

Question 20

Match the following phenotypes with the most probable genotype in the Weiner nomenclature.
-DCe

Accepted Answer

A) R1r 
B) R1R1 
C) R2R2 
D) rr 
A) R1r 
B) R1R1 
C) R2R2 
D) rr

The weak D test detects:

Match the Fisher-Race notation with the correct Weiner notation for the following: -r^y

A patient phenotypes as D+C+E-c-e+.The most likely genotype is:

Why is the determination of the D antigen important for women during pregnancy?

Match the Fisher-Race notation with the correct Weiner notation for the following: -r'

The LW antigen expression is typically stronger on __________ cells.

If a D-positive person appears to have anti-D in their serum,the most likely explanation is:

Match the Fisher-Race notation with the correct Weiner notation for the following: -R⁰

The frequency of the D-negative phenotype in the population is:

How would a donor who tested negative with anti-D reagent in the immediate spin test but tested positive at antihuman globulin with anti-D reagent be labeled?

The inheritance of the Rh antigens are:

All of the following can cause the D antigen expression to be weaker except:

Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DcE

How is it genetically possible for a child to phenotype as D-negative?

Most Rh system antibodies are of which immunoglobulin class?

Current theory regarding the genetics of the Rh system suggests that:

Which of the following phenotypes will react with anti-f?

The numeric Rh4 nomenclature refers to which antigen in the Rosenfield notation?

Testing for the weak D expression is performed by:

Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DCe

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Filters

Exam 5: Rh Blood Group System

The weak D test detects:

Match the Fisher-Race notation with the correct Weiner notation for the following: -ry

A patient phenotypes as D+C+E-c-e+.The most likely genotype is:

Why is the determination of the D antigen important for women during pregnancy?

Match the Fisher-Race notation with the correct Weiner notation for the following: -r'

The LW antigen expression is typically stronger on __________ cells.

If a D-positive person appears to have anti-D in their serum,the most likely explanation is:

Match the Fisher-Race notation with the correct Weiner notation for the following: -R0

The frequency of the D-negative phenotype in the population is:

How would a donor who tested negative with anti-D reagent in the immediate spin test but tested positive at antihuman globulin with anti-D reagent be labeled?

The inheritance of the Rh antigens are:

All of the following can cause the D antigen expression to be weaker except:

Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DcE

How is it genetically possible for a child to phenotype as D-negative?

Most Rh system antibodies are of which immunoglobulin class?

Current theory regarding the genetics of the Rh system suggests that:

Which of the following phenotypes will react with anti-f?

The numeric Rh4 nomenclature refers to which antigen in the Rosenfield notation?

Testing for the weak D expression is performed by:

Match the following phenotypes with the most probable genotype in the Weiner nomenclature. -DCe

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Abo and H Blood Group Systems and Secretor Status

Other Blood Group Systems

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Filters

Match the Fisher-Race notation with the correct Weiner notation for the following: -r^y

Match the Fisher-Race notation with the correct Weiner notation for the following: -R⁰