Question 1

Type II hypersensitivities appear to be responsible for the tissue damage in all of the following except:

Accepted Answer

A) rheumatic fever following strep throat infections 
B) transfusion reactions 
C) hemolytic disease of the newborn 
D) lupus erythematosus 
A) rheumatic fever following strep throat infections 
B) transfusion reactions 
C) hemolytic disease of the newborn 
D) lupus erythematosus

Question 2

Which of the following statements about immunological tests is incorrect?

Accepted Answer

A) Neutralization tests can detect bacterial toxins, but not anti-viral antibodies. 
B) Three tagged antibody tests include RIA, FACS, and ELISA. 
C) Agglutination reactions can be used to determine the antibody titer. 
D) Home pregnancy tests are modified agglutination assays. 
A) Neutralization tests can detect bacterial toxins, but not anti-viral antibodies. 
B) Three tagged antibody tests include RIA, FACS, and ELISA. 
C) Agglutination reactions can be used to determine the antibody titer. 
D) Home pregnancy tests are modified agglutination assays.

Question 3

Which of the following statements about cytotoxic hypersensitivity is correct?

Accepted Answer

A) Normally a person's serum has IgM against the antigens on their own red blood cells. 
B) Adverse transfusion reactions are no longer a problem because transfusions rarely occur. 
C) Hemolytic disease of the newborn cannot be prevented. 
D) Sensitization to Rh antigens can occur during delivery, miscarriage or abortion. 
A) Normally a person's serum has IgM against the antigens on their own red blood cells. 
B) Adverse transfusion reactions are no longer a problem because transfusions rarely occur. 
C) Hemolytic disease of the newborn cannot be prevented. 
D) Sensitization to Rh antigens can occur during delivery, miscarriage or abortion.

Question 4

Rheumatoid arthritis:

Accepted Answer

A) involves autoantibodies that are against the acetylcholine receptors 
B) form IgM:IgG immune complexes and TH1 cells which initiate inflammation in joints 
C) mainly affects the joints of the hands and the joints 
D) two of the above 
A) involves autoantibodies that are against the acetylcholine receptors 
B) form IgM:IgG immune complexes and TH1 cells which initiate inflammation in joints 
C) mainly affects the joints of the hands and the joints 
D) two of the above

Question 5

Imagine you have a sibling that needs a kidney transplant. You offer to give your kidney. What reaction against the red blood cells in the donor kidney would occur if you had different blood groups? Even if you had the same blood groups why might you not be able to give her one of your kidneys?

Accepted Answer

If you and your sibling have different b

Question 6

A tuberculin skin test _____.

Accepted Answer

A) is read by the diameter and the elevation of the induration 
B) is negative if a person has received the BCG vaccine 
C) is read by the redness of the induration 
D) two of the above 
A) is read by the diameter and the elevation of the induration 
B) is negative if a person has received the BCG vaccine 
C) is read by the redness of the induration 
D) two of the above

Question 7

Allergens bind to sensitized mast cells carrying surface ____ molecules,causing degranulation.

Accepted Answer

A) IgG 
B) IgB 
C) IgM 
D) IgE 
A) IgG 
B) IgB 
C) IgM 
D) IgE

Question 8

Drug reactions:

Accepted Answer

A) are associated with only 3 of the 4 types of hypersensitivities 
B) are common because most drug molecules are large enough to act as allergens 
C) can occur with antibiotics 
D) two of the above 
A) are associated with only 3 of the 4 types of hypersensitivities 
B) are common because most drug molecules are large enough to act as allergens 
C) can occur with antibiotics 
D) two of the above

Question 9

In HIV testing ELISA detects _________ while Western blot detects ________.

Accepted Answer

A) HIV antibodies, HIV antigen proteins 
B) HIV proteins, HIV reverse transcriptase 
C) HIV capsid proteins, HIV carbohydrates 
D) HIV antibodies, HIV antibody complexes 
A) HIV antibodies, HIV antigen proteins 
B) HIV proteins, HIV reverse transcriptase 
C) HIV capsid proteins, HIV carbohydrates 
D) HIV antibodies, HIV antibody complexes

Question 10

Cell-mediated hypersensitivity is mediated by _____.

Accepted Answer

A) IgG, IgM 
B) T cells 
C) mast cells 
D) two of the above 
A) IgG, IgM 
B) T cells 
C) mast cells 
D) two of the above

Question 11

Antigenic or molecular mimicry _____.

Accepted Answer

A) occurs when T cells attack tissue antigens similar to bacterial antigens 
B) involves self reactive T cells hiding in the thymus 
C) leads to an increase in the number of regulatory T cells 
D) none of the above 
A) occurs when T cells attack tissue antigens similar to bacterial antigens 
B) involves self reactive T cells hiding in the thymus 
C) leads to an increase in the number of regulatory T cells 
D) none of the above

Question 12

People with HIV are susceptible to many infections.Which sets of cells are destroyed?

Accepted Answer

A) white blood cells and red blood cells 
B) TC cells and B cells 
C) TH cells and macrophages 
D) macrophages and polymorphonuclear leukocytes (PMNLs) 
A) white blood cells and red blood cells 
B) TC cells and B cells 
C) TH cells and macrophages 
D) macrophages and polymorphonuclear leukocytes (PMNLs)

Question 13

Severe combined immunodeficiency (SCID)is a life threatening condition. Its treatment includes _____.

Accepted Answer

A) bone marrow transplants 
B) immunosuppressive drugs 
C) steroids 
D) two of the above 
A) bone marrow transplants 
B) immunosuppressive drugs 
C) steroids 
D) two of the above

Question 14

Rhogam,which is administered to women during pregnancy to prevent the occurrence of hemolytic disease of the newborn,contains:

Accepted Answer

A) Rh positive antigen 
B) Rh negative antigen 
C) Anti-Rh antibodies (IgG) 
D) two of the above 
A) Rh positive antigen 
B) Rh negative antigen 
C) Anti-Rh antibodies (IgG) 
D) two of the above

Question 15

Which is the main cellular mediator released during degranulation of mast cells is associated with capillary dilation (capillaries become more permeable)?

Accepted Answer

A) Interleukins 
B) Histamine 
C) Antihistamine 
D) IgG 
A) Interleukins 
B) Histamine 
C) Antihistamine 
D) IgG

Question 16

Which of the following could result in a Type II hypersensitivity?

Accepted Answer

A) a patient with A blood given B blood by mistake 
B) an Rh-negative mother carrying an Rh-positive fetus 
C) an Rh-positive mother carrying an Rh-negative fetus 
D) two of the above 
A) a patient with A blood given B blood by mistake 
B) an Rh-negative mother carrying an Rh-positive fetus 
C) an Rh-positive mother carrying an Rh-negative fetus 
D) two of the above

Question 17

Which of the following is an immunological test based on precipitins (antibodies)which form a visible precipitate with antigens?

Accepted Answer

A) agglutination 
B) radial immunodiffusion 
C) immunoelectrophoresis 
D) two of the above 
A) agglutination 
B) radial immunodiffusion 
C) immunoelectrophoresis 
D) two of the above

Question 18

The blocking antibodies formed in response to desensitization are composed of which class of antibody?

Accepted Answer

A) IgG 
B) IgD 
C) IgA 
D) IgM 
A) IgG 
B) IgD 
C) IgA 
D) IgM

Question 19

To treat generalized anaphylaxis,_________ must be administered immediately.

Accepted Answer

A) histamine 
B) epinephrine 
C) prostaglandins 
D) antibiotics 
A) histamine 
B) epinephrine 
C) prostaglandins 
D) antibiotics

Question 20

Which of the following is an example of lower respiratory anaphylaxis?

Accepted Answer

A) Tuberculosis 
B) Legionnaire's disease 
C) Hay fever 
D) Asthma 
A) Tuberculosis 
B) Legionnaire's disease 
C) Hay fever 
D) Asthma

Exam 18: Immunology Ii: Immunological Disorders and Tests

Type II hypersensitivities appear to be responsible for the tissue damage in all of the following except:

Which of the following statements about immunological tests is incorrect?

Which of the following statements about cytotoxic hypersensitivity is correct?

Rheumatoid arthritis:

Imagine you have a sibling that needs a kidney transplant. You offer to give your kidney. What reaction against the red blood cells in the donor kidney would occur if you had different blood groups? Even if you had the same blood groups why might you not be able to give her one of your kidneys?

A tuberculin skin test _____.

Allergens bind to sensitized mast cells carrying surface ____ molecules,causing degranulation.

Drug reactions:

In HIV testing ELISA detects _________ while Western blot detects ________.

Cell-mediated hypersensitivity is mediated by _____.

Antigenic or molecular mimicry _____.

People with HIV are susceptible to many infections.Which sets of cells are destroyed?

Severe combined immunodeficiency (SCID)is a life threatening condition. Its treatment includes _____.

Rhogam,which is administered to women during pregnancy to prevent the occurrence of hemolytic disease of the newborn,contains:

Which is the main cellular mediator released during degranulation of mast cells is associated with capillary dilation (capillaries become more permeable)?

Which of the following could result in a Type II hypersensitivity?

Which of the following is an immunological test based on precipitins (antibodies)which form a visible precipitate with antigens?

The blocking antibodies formed in response to desensitization are composed of which class of antibody?

To treat generalized anaphylaxis,_________ must be administered immediately.

Which of the following is an example of lower respiratory anaphylaxis?

Scope and History of Microbiology

Fundamentals of Chemistry

Microscopy and Staining

Characteristics of Prokaryotic and Eukaryotic Cells

Essential Concepts of Metabolism

Growth and Culturing of Bacteria

Microbial Genetics

Gene Transfer and Genetic Engineering

An Introduction to Taxonomy: the Bacteria

Viruses

Eukaryotic Microorganisms and Parasites

Sterilization and Disinfection

Antimicrobial Therapy

Host-Microbe Relationships and Disease Processes

Epidemiology and Nosocomial Infections

Innate Host Defenses

Immunology I: Basic Principles of Adaptive Immunity and Immunization

Diseases of the Skin and Eyes; Wounds and Bites

Urogenital and Sexually Transmitted Diseases

Diseases of the Respiratory System

Oral and Gastrointestinal Diseases

Cardiovascular, lymphatic and Systemic Disease

Diseases of the Nervous System

Environmental Microbiology

Applied Microbiology

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In HIV testing ELISA detects _ while Western blot detects .