Exam 6: Enzymes: the Catalysts of Life

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Azidothymidine (AZT)is a(n)________ used in the treatment of AIDS and targets the enzyme reverse transcriptase.

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Which of the following is/are means whereby a catalyst can lower the activation energy of a reaction?

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Enzyme activity may be regulated by several means.Can you identify the mode of regulation for each of the following examples? a.When glucose is converted to glucose-6-phosphate by hexokinase,the accumulation of glucose-6-phosphate inhibits the reaction. b.A foreign substance is added to the reaction in part a above.This substance binds to hexokinase and prevents its ability to catalyze the reaction. c.An inactive form of an enzyme becomes active after being phosphorylated. d.Pepsinogen becomes pepsin after being released into the lumen of the stomach. e.In a series of enzymatic reactions,it is found that the product of the last reaction inhibits the first enzyme in the series of reactions.

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In the Eadie-Hofstee plot,

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An enzyme influences the structure of which of the following?

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Which of the following is an example of a prosthetic group?

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Which of the following is an enzyme?

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The active site for carboxypeptidase

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The site on an enzyme that is designated for the substrate bind is called the ________.

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Mixed type inhibitors will affect the ________ of an enzymatic reaction.

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Match the symbol on the left with its description on the right.
[S]
slope of the Eadie-Hofstee plot
-1/Km
maximum velocity
Km/Vmax
Michaelis-Menten constant
Correct Answer:
Verified
Premises:
Responses:
[S]
slope of the Eadie-Hofstee plot
-1/Km
maximum velocity
Km/Vmax
Michaelis-Menten constant
Km
turnover number
kcat
substrate concentration
Vmax
slope of Michaelis-Menten plot
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Nonprotein catalysts are known as ________.

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According to the EC system,which is not one of the major groups of enzymes?

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An organism that is labeled a cryophile is capable of

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Match the choice on the left with the correct choice on the right.
double-reciprocal
trypsin
ribozymes
distortion of substrate and enzyme
feedback inhibition
Lineweaver-Burk
Correct Answer:
Verified
Premises:
Responses:
double-reciprocal
trypsin
ribozymes
distortion of substrate and enzyme
feedback inhibition
Lineweaver-Burk
prosthetic group
RNA
induced-fit model
DNA
proteolytic cleavage
zinc
covalent modification
protein kinases
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As new enzymes are discovered,the EC system for naming enzymes is to be used.The names are to be based on which of the following criteria?

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The Michaelis constant

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The ________ is the minimum energy required before two molecules can be successful in producing a reaction.

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