Exam 32: Drugs for Skin Disorders

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What is the treatment of lice and scabies infestations and what tips would you give the patient or patient's family?

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The preferred drug for lice and scabies infestation is permethrin. This drug is considered the safest agent, especially for infants and children. Pyrethrin is a related product which is also widely used to kill lice and their eggs on contact.
Tips: Apply the permethrin cream to the entire skin surface and allow it to remain for eight to 14 hours before bathing. Itching may continue for several weeks as the dead mites are removed from the skin. A newer entry to the market, dimethicone, is applied to dry hair, massaged in until hair is completely wet, and left on for 30 minutes, and then the hair is combed with a lice comb. The solution is allowed to dry on the hair for at least eight hours and then the hair is washed. All scabicides and pediculicides must be used strictly as directed because excessive use has the potential to cause serious systemic effects and skin irritation. While applying the drugs for the treatment of lice or mites, care must be taken to avoid the mouth, open skin lesions, or eyes because exposure the drug will cause severe irritation. Lice lay eggs, which are called nits. Fine-toothed nit combs are useful in removing nits after the lice have been killed. Patients should comb the infested area after the hair has been dried. To ensure that drug therapy is effective, patients should inspect hair shafts daily for at least one week after treatment. Because nits may be present in bedding and other upholstery material, all material coming in close contact with the patient should be washed in hot water or treated with the appropriate agent. Advise patients to inform family members, sexual partners, school personnel, and any other persons with whom close contact has occurred about skin infestations. Clothes, bed linens, and personal items should be treated properly to avoid reinfestation. Ensure that patients using pediculicides repeat the treatment in seven to 10 days to increase its effectiveness.

Describe the treatment of rosacea.

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The two most effective treatments for rosacea are topical metronidazole and azelaic acid. Alternative medications include topical clindamycin and erythromycin. Tetracycline antibiotics are beneficial to patients with rosacea with multiple pustules or with ocular involvement. Severe, resistant cases may respond to isotretinoin.

The pharmacist is teaching a patient about systemic medications that are used to treat psoriasis. Which medications are appropriate for the pharmacist to include in this teaching session? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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C, D

Scabicides are used to treat lice and pediculicides are used to treat scabies.

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A patient taking tretinoin requires blood draws to monitor for side effects while taking the medication. Which lab orders does the pharmacist anticipate for this patient? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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A mother of a school-aged child asks the pharmacist why her child continues to have itching with no sign of mites. Which response by the pharmacist is the most appropriate?

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The subcutaneous layer of the skin is called the hypodermis.

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A patient taking carbamazepine for seizures has also been started on isotretinoin/13-cis-retinoic acid. What is this patient at an increased risk for?

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List the common treatments for psoriasis and why they are used.

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What value will require periodic monitoring for the patient taking isotretinoin/13-cis-retinoic acid?

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A patient with psoriasis asks the pharmacist if there is a topical therapy that may be used without other medications for psoriasis. Which response by the pharmacist is the most appropriate?

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Urticaria, referred to as itchiness, commonly occurs with allergic reactions.

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This sublayer of the epidermis supplies the epidermis with new cells after older superficial cells have been damaged or lost by normal wear.

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The pharmacist instructs the mother of a school-age child with lice to prevent re-infestation. What should the pharmacist include in the teaching session? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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Betamethasone valerate is a topical corticosteroid with medium potency.

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Ensure that patients using pediculicides repeat the treatment in 2 to 5 days to increase its effectiveness.

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The pharmacist is caring for a patient using amcinonide. What teaching instructions will the pharmacist provide for this patient?

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The pharmacist is teaching a patient about age-related changes in the skin. What should the pharmacist include in the teaching session? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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