Exam 12: Drugs for Seizures

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Explain how the different classes of drugs to treat seizures and epilepsy work.

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Succinimides delay calcium entry into neurons, prolonging the threshold of the impulse; when the nerve is busy firing, it cannot misfire; hydantoins inhibit the influx of sodium ions thereby stopping some impulses from starting; benzodiazepines and barbiturates act like the neurotransmitter GABA by stimulating an influx of chloride ions, which stop the impulse and reduce misfiring.

An epileptic patient may discontinue their medication at any time without side effects.

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The patient taking phenytoin asks the pharmacist what the side effects of the drug are. What should the pharmacist include in the response? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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A,B,C

The patient is being admitted to the labor and delivery unit. The patient informs the nurse she has had high blood pressure since week 32 of this pregnancy. Upon assessment, the nurse finds edema. The patient relates that she has an occasional headache. Before the nurse leaves the room, the patient begins to have a seizure. What pregnancy disorder is this patient experiencing?

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The pharmacist is teaching a patient about medications for seizures. Which items should be included in this teaching? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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The pharmacist is preparing a presentation about antiseizure medications. The pharmacist plans to include the general mechanisms of actions for these medications. Which items would be appropriate to include? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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A disorder of electrical activity in the brain resulting in the occurrence of periods of unconsciousness, seizures and convulsions is called epilepsy.

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List the known causes of seizures.

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The pharmacist is caring for a patient with absence seizures. Which medication would be appropriate to treat absence seizures?

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If the neuronal threshold is elevated, nerves cannot misfire and cause seizures.

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Hydantoins, by increasing the influx of sodium ions, decrease neuronal activity and seizures.

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A patient with a history of seizures is taking phenytoin. Based on this medication prescription, what is the patient at an increased risk for developing?

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In order to monitor the effectiveness of drug therapy in a patient with seizures, what should the pharmacist teach the patient to do? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

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Explain the statement: All convulsions are seizures but not all seizures are convulsions.

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The goal of anti-seizure medication is to completely suppress neuronal activity in the brain.

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Extreme metabolic shifts may cause seizures.

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Clients with epilepsy may appear normal and asymptomatic.

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