Exam 20: Drugs for Lipid Disorders

Monoamine oxidase is inhibited by statins and serves as the primary regulator of cholesterol biosynthesis.

Because it is not soluble in blood, very little cholesterol actually travels through the blood in its free form.

The patient has an HDL cholesterol value of 0.7 mmol/L. What is the most appropriate interpretation of this value by the pharmacist?

Which instructions by the pharmacist are appropriate for a patient who wants to decrease the cholesterol level? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

The pharmacy technician instructs the patient that which foods contain high amounts of Omega-3 fatty acids? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

Very low density lipoproteins (VLDL) is converted to LDL, via the help of lipoprotein lipase, as it travels through the bloodstream.

The patient has been taking nicotinic acid. Which adverse effects are common with nicotinic acid? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

The patient is going to be started on cholestyramine three times daily. What instruction should the pharmacist provide to this patient?

Patients at high risk that are started on drug therapy do not need to continue their lifestyle changes.

These substances are water soluble and can be transported freely throughout the blood, carrying cholesterol.

What is the major storage form of fat in the body and the only type of lipid that serves as an important energy source?

HDL stands for high-density lipoproteins and is considered bad cholesterol.

The pharmacist is caring for a patient who asks why LDL (low-density lipoprotein) is called the "bad" cholesterol. Which response by the pharmacist is most appropriate?

What is the role of HDL in the body?

These are the major storage form of fat in the body and the only type of lipid that serves as an important energy source.

S.V., age 57, a smoker and heavy drinker, has recently been diagnosed with hyperlipidemia and hypercholesterolemia. His grandfather suffered a fatal heart attack at age 60. His father suffered a heart attack at age 62 and survived. S.V.'s brother also has elevated cholesterol and lipid levels and has had angioplasty. The physician recommends S.V. adopt several life style modifications as well as take the medication atorvastatin. -What lifestyle changes would help S.V. to lower his cholesterol levels?

S.V., age 57, a smoker and heavy drinker, has recently been diagnosed with hyperlipidemia and hypercholesterolemia. His grandfather suffered a fatal heart attack at age 60. His father suffered a heart attack at age 62 and survived. S.V.'s brother also has elevated cholesterol and lipid levels and has had angioplasty. The physician recommends S.V. adopt several life style modifications as well as take the medication atorvastatin. -S.V. calls the pharmacy 2 weeks after beginning the medication. He wants to purchase a cholesterol home test today to see if the medication is working yet. What should you tell S.V.?

The statins have been shown to slow the progression of coronary artery disease and to reduce mortality from cardiovascular disease.

S.V., age 57, a smoker and heavy drinker, has recently been diagnosed with hyperlipidemia and hypercholesterolemia. His grandfather suffered a fatal heart attack at age 60. His father suffered a heart attack at age 62 and survived. S.V.'s brother also has elevated cholesterol and lipid levels and has had angioplasty. The physician recommends S.V. adopt several life style modifications as well as take the medication atorvastatin. -At his 6 week checkup, S.V., who loves to start his day with a full glass of grapefruit juice, complains to the doctor of muscle aches that were not there before starting lipid lowering therapy. What action should be taken at this time and why?

Hyperlipidemia, or hypercholesterolemia, are the result of a combination of genetic and environmental (lifestyle) factors.