Question 1

When most drugs enter the body, they bind to a specific receptor and can alter normal physiological processes.

Accepted Answer

A) True 
 B)False  True

Question 2

A dose-response curve is useful in determining which of the following?

Accepted Answer

A)  Rates of drug elimination 
B)  The drug's volume of distribution 
C)  The number of genes involved in that drugs metabolism 
D)  A drug's potency 
E)  The best route of administration 
A)  Rates of drug elimination 
B)  The drug's volume of distribution 
C)  The number of genes involved in that drugs metabolism 
D)  A drug's potency 
E)  The best route of administration D

Question 3

How is the therapeutic index (TI) used?

Accepted Answer

A)  To determine if a drug is ergolytic 
B)  To determine the relative safety of a drug 
C)  To determine the potency of a drug 
D)  To determine the efficacy of a drug 
E)  To determine the rate that a drug is metabolized 
A)  To determine if a drug is ergolytic 
B)  To determine the relative safety of a drug 
C)  To determine the potency of a drug 
D)  To determine the efficacy of a drug 
E)  To determine the rate that a drug is metabolized B

Question 4

Which of the following is not considered a fundamental component of pharmacokinetics?

Accepted Answer

A)  Drug metabolism 
B)  Down regulation of drug receptors 
C)  Drug elimination 
D)  Drug absorption 
E)  Drug distribution 
A)  Drug metabolism 
B)  Down regulation of drug receptors 
C)  Drug elimination 
D)  Drug absorption 
E)  Drug distribution

Question 5

During moderate- to high-intensity exercise, why is the bioavailability of most drugs altered?

Accepted Answer

A)  Serum proteins bind drugs tighter - with higher affinity 
B)  Drugs are taken up faster in the stomach 
C)  Blood flow decreases to the liver and kidneys 
D)  Metabolism in muscle tissue increases significantly 
E)  The rate of sweat formation increases significantly 
A)  Serum proteins bind drugs tighter - with higher affinity 
B)  Drugs are taken up faster in the stomach 
C)  Blood flow decreases to the liver and kidneys 
D)  Metabolism in muscle tissue increases significantly 
E)  The rate of sweat formation increases significantly

Question 6

Drug tolerance is when more drug is needed to get the same desired effect over time.

Accepted Answer

A) True 
 B)False

Question 7

An ergogenic drug is one that does what?

Accepted Answer

A)  Improves exercise performance 
B)  Increases the rate of elimination 
C)  Causes performance to deteriorate 
D)  Alters the rate of metabolism of other drugs 
E)  Displaces drugs from non-specific binding sites 
A)  Improves exercise performance 
B)  Increases the rate of elimination 
C)  Causes performance to deteriorate 
D)  Alters the rate of metabolism of other drugs 
E)  Displaces drugs from non-specific binding sites

Question 8

What is the name for a drug that binds and activates a receptor similar to the endogenous molecule?

Accepted Answer

A)  An antagonist 
B)  An agonist 
C)  A competitive inhibitor 
D)  A suicide substrate 
E)  An allosteric effector 
A)  An antagonist 
B)  An agonist 
C)  A competitive inhibitor 
D)  A suicide substrate 
E)  An allosteric effector

Question 9

Some drugs that are taken over a long period of time can cause significant problems when their use is abruptly stopped. Which of the following is true regarding these problems?

Accepted Answer

A)  They are called a withdrawal syndrome. 
B)  They are due to the ergogenic nature of the drug. 
C)  They are determined from dose-response curves. 
D)  They are based mostly on the pharmacokinetic properties of the drug. 
E)  They are dependent of the liver status of the individual. 
A)  They are called a withdrawal syndrome. 
B)  They are due to the ergogenic nature of the drug. 
C)  They are determined from dose-response curves. 
D)  They are based mostly on the pharmacokinetic properties of the drug. 
E)  They are dependent of the liver status of the individual.

Question 10

Examination of the dose-response curves for related drugs can help determine which drug has the highest efficacy.

Accepted Answer

A) True 
 B)False

Question 11

Intense exercise rarely alters a drug's bioavailability.

Accepted Answer

A) True 
 B)False

Question 12

The therapeutic window is the desired range of blood concentration that is not toxic but still provides therapy.

Accepted Answer

A) True 
 B)False

Question 13

In an obese patient, would the dose of a fat-soluble drug be increased or decreased, and why?

Accepted Answer

A)  Decreased due to the weight of the individual 
B)  Increased due to a slow rate of absorption 
C)  Decreased due to lower amounts bound to serum proteins 
D)  Increased due to an increase in the volume of distribution 
E)  Decreased due to added stress on the kidneys 
A)  Decreased due to the weight of the individual 
B)  Increased due to a slow rate of absorption 
C)  Decreased due to lower amounts bound to serum proteins 
D)  Increased due to an increase in the volume of distribution 
E)  Decreased due to added stress on the kidneys

Question 14

All humans contain the exact same enzymes, so drug metabolism is the same for all races.

Accepted Answer

A) True 
 B)False

Question 15

Whether a person responds to a drug or shows unwanted side effects is probably due to the interactions of several genes.

Accepted Answer

A) True 
 B)False

When most drugs enter the body, they bind to a specific receptor and can alter normal physiological processes.

A dose-response curve is useful in determining which of the following?

How is the therapeutic index (TI) used?

Which of the following is not considered a fundamental component of pharmacokinetics?

During moderate- to high-intensity exercise, why is the bioavailability of most drugs altered?

Drug tolerance is when more drug is needed to get the same desired effect over time.

An ergogenic drug is one that does what?

What is the name for a drug that binds and activates a receptor similar to the endogenous molecule?

Some drugs that are taken over a long period of time can cause significant problems when their use is abruptly stopped. Which of the following is true regarding these problems?

Examination of the dose-response curves for related drugs can help determine which drug has the highest efficacy.

Intense exercise rarely alters a drug's bioavailability.

The therapeutic window is the desired range of blood concentration that is not toxic but still provides therapy.

In an obese patient, would the dose of a fat-soluble drug be increased or decreased, and why?

All humans contain the exact same enzymes, so drug metabolism is the same for all races.

Whether a person responds to a drug or shows unwanted side effects is probably due to the interactions of several genes.

Basics of Exercise Performance

Autonomic Pharmacology and Stress

Beta-Blockers and Cardiovascular Disease

Cardiovascular Drugs and Hypertension

Diuretics

Respiratory Agents

Sympathomimetics

Psychotherapeutic Agents

Lipid-Modifying Agents

Analgesics and Anti-Inflammatory Drugs

Antidiabetic and Antiobesity Drugs

Dietary Supplements

Caffeine

Ethanol, Nicotine, and Cannabis

Performance Enhancing Substances

Filters

Exam 1: Basic Pharmacology

When most drugs enter the body, they bind to a specific receptor and can alter normal physiological processes.

A dose-response curve is useful in determining which of the following?

How is the therapeutic index (TI) used?

Which of the following is not considered a fundamental component of pharmacokinetics?

During moderate- to high-intensity exercise, why is the bioavailability of most drugs altered?

Drug tolerance is when more drug is needed to get the same desired effect over time.

An ergogenic drug is one that does what?

What is the name for a drug that binds and activates a receptor similar to the endogenous molecule?

Some drugs that are taken over a long period of time can cause significant problems when their use is abruptly stopped. Which of the following is true regarding these problems?

Examination of the dose-response curves for related drugs can help determine which drug has the highest efficacy.

Intense exercise rarely alters a drug's bioavailability.

The therapeutic window is the desired range of blood concentration that is not toxic but still provides therapy.

In an obese patient, would the dose of a fat-soluble drug be increased or decreased, and why?

All humans contain the exact same enzymes, so drug metabolism is the same for all races.

Whether a person responds to a drug or shows unwanted side effects is probably due to the interactions of several genes.

Basics of Exercise Performance

Autonomic Pharmacology and Stress

Beta-Blockers and Cardiovascular Disease

Cardiovascular Drugs and Hypertension

Diuretics

Respiratory Agents

Sympathomimetics

Psychotherapeutic Agents

Lipid-Modifying Agents

Analgesics and Anti-Inflammatory Drugs

Antidiabetic and Antiobesity Drugs

Dietary Supplements

Caffeine

Ethanol, Nicotine, and Cannabis

Performance Enhancing Substances

Filters