Question 1

Lipid-modifying drugs like statins are only useful in the small percentage of the population that has a genetic problem in cholesterol transport.

Accepted Answer

A) True 
 B)False  False

Question 2

Aspirin is sometimes given in conjunction with niacin to do which of the following?

Accepted Answer

A)  Further decrease LDL levels 
B)  Stimulate lipoprotein lipase activity 
C)  Minimize flushing/hot flashes 
D)  Increase the activity of the G-protein coupled receptor 
E)  Increase the amount of inhibition of HMG-CoA-reductase 
A)  Further decrease LDL levels 
B)  Stimulate lipoprotein lipase activity 
C)  Minimize flushing/hot flashes 
D)  Increase the activity of the G-protein coupled receptor 
E)  Increase the amount of inhibition of HMG-CoA-reductase C

Question 3

With regular aerobic exercise, slow twitch muscle cells, which are more efficient users of lipid sources for energy, help improve the lipid profile.

Accepted Answer

A) True 
 B)False  True

Question 4

How do statins primarily work?

Accepted Answer

A)  By increasing muscle metabolism 
B)  By increasing lipoprotein lipase activity 
C)  By activating PPAR signaling pathways 
D)  By degrading LDL 
E)  By inhibiting HMG-CoA-reductase 
A)  By increasing muscle metabolism 
B)  By increasing lipoprotein lipase activity 
C)  By activating PPAR signaling pathways 
D)  By degrading LDL 
E)  By inhibiting HMG-CoA-reductase

Question 5

When exercising, the only source of fat available to working muscle is provided by adipose tissue.

Accepted Answer

A) True 
 B)False

Question 6

The atherogenic triad includes all of the following EXCEPT:

Accepted Answer

A)  High VLDL 
B)  Low HDL 
C)  High LDL 
D)  Elevated triglycerides 
A)  High VLDL 
B)  Low HDL 
C)  High LDL 
D)  Elevated triglycerides

Question 7

Muscle pain has been noted with use of statins independently of intense exercise.

Accepted Answer

A) True 
 B)False

Question 8

Lipoprotein lipase releases free fatty acids and glycerol from serum triglycerides.

Accepted Answer

A) True 
 B)False

Question 9

What is the effect of exercise on the pharmacokinetics of lipid-modifying agents?

Accepted Answer

A)  Minimal because these drugs are taken at bedtime 
B)  Very pronounced because of the involvement of the liver in cholesterol levels 
C)  Varies greatly amongst the different classes of compounds 
D)  Important because all these drugs are flow-limited 
E)  Totally dependent on the fitness level of the patient 
A)  Minimal because these drugs are taken at bedtime 
B)  Very pronounced because of the involvement of the liver in cholesterol levels 
C)  Varies greatly amongst the different classes of compounds 
D)  Important because all these drugs are flow-limited 
E)  Totally dependent on the fitness level of the patient

Question 10

Only long bouts of endurance exercise can dramatically alter the blood lipd profile.

Accepted Answer

A) True 
 B)False

Question 11

The increase in lipoprotein lipase activity during exercise results in which of the following?

Accepted Answer

A)  It causes a huge decrease in LDL 
B)  It causes triglyceride breakdown and speeds clearance of VLDL 
C)  It decreases HDL 
D)  It causes large changes in total cholesterol 
E)  It is dependent on PPAR signaling in both liver and muscle tissue 
A)  It causes a huge decrease in LDL 
B)  It causes triglyceride breakdown and speeds clearance of VLDL 
C)  It decreases HDL 
D)  It causes large changes in total cholesterol 
E)  It is dependent on PPAR signaling in both liver and muscle tissue

Question 12

In a blood test, a good indicator of muscle cell damage is the level of _________.

Accepted Answer

The answer of In a blood test, a good indicator...

Question 13

Hyperlipidemia is a positive risk factor for cardiovascular disease but can be completely controlled with an appropriate diet and exercise.

Accepted Answer

A) True 
 B)False

Question 14

During recovery after a bout of exercise, muscle continues uptake of lipoproteins from the blood for several hours, depending on the intensity and energy expenditure that occurred during exercise.

Accepted Answer

A) True 
 B)False

Question 15

What is a desirable level of total cholesterol in the blood?

Accepted Answer

A)  Over 240 
B)  Less than 200 
C)  40-60 
D)  Directly associated with triglyceride levels 
E)  Nearly impossible to properly maintain 
A)  Over 240 
B)  Less than 200 
C)  40-60 
D)  Directly associated with triglyceride levels 
E)  Nearly impossible to properly maintain

Lipid-modifying drugs like statins are only useful in the small percentage of the population that has a genetic problem in cholesterol transport.

Aspirin is sometimes given in conjunction with niacin to do which of the following?

With regular aerobic exercise, slow twitch muscle cells, which are more efficient users of lipid sources for energy, help improve the lipid profile.

How do statins primarily work?

When exercising, the only source of fat available to working muscle is provided by adipose tissue.

The atherogenic triad includes all of the following EXCEPT:

Muscle pain has been noted with use of statins independently of intense exercise.

Lipoprotein lipase releases free fatty acids and glycerol from serum triglycerides.

What is the effect of exercise on the pharmacokinetics of lipid-modifying agents?

Only long bouts of endurance exercise can dramatically alter the blood lipd profile.

The increase in lipoprotein lipase activity during exercise results in which of the following?

In a blood test, a good indicator of muscle cell damage is the level of _________.

Hyperlipidemia is a positive risk factor for cardiovascular disease but can be completely controlled with an appropriate diet and exercise.

During recovery after a bout of exercise, muscle continues uptake of lipoproteins from the blood for several hours, depending on the intensity and energy expenditure that occurred during exercise.

What is a desirable level of total cholesterol in the blood?

Basic Pharmacology

Basics of Exercise Performance

Autonomic Pharmacology and Stress

Beta-Blockers and Cardiovascular Disease

Cardiovascular Drugs and Hypertension

Diuretics

Respiratory Agents

Sympathomimetics

Psychotherapeutic Agents

Analgesics and Anti-Inflammatory Drugs

Antidiabetic and Antiobesity Drugs

Dietary Supplements

Caffeine

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Exam 10: Lipid-Modifying Agents

Lipid-modifying drugs like statins are only useful in the small percentage of the population that has a genetic problem in cholesterol transport.

Aspirin is sometimes given in conjunction with niacin to do which of the following?

With regular aerobic exercise, slow twitch muscle cells, which are more efficient users of lipid sources for energy, help improve the lipid profile.

How do statins primarily work?

When exercising, the only source of fat available to working muscle is provided by adipose tissue.

The atherogenic triad includes all of the following EXCEPT:

Muscle pain has been noted with use of statins independently of intense exercise.

Lipoprotein lipase releases free fatty acids and glycerol from serum triglycerides.

What is the effect of exercise on the pharmacokinetics of lipid-modifying agents?

Only long bouts of endurance exercise can dramatically alter the blood lipd profile.

The increase in lipoprotein lipase activity during exercise results in which of the following?

In a blood test, a good indicator of muscle cell damage is the level of _________.

Hyperlipidemia is a positive risk factor for cardiovascular disease but can be completely controlled with an appropriate diet and exercise.

During recovery after a bout of exercise, muscle continues uptake of lipoproteins from the blood for several hours, depending on the intensity and energy expenditure that occurred during exercise.

What is a desirable level of total cholesterol in the blood?

Basic Pharmacology

Basics of Exercise Performance

Autonomic Pharmacology and Stress

Beta-Blockers and Cardiovascular Disease

Cardiovascular Drugs and Hypertension

Diuretics

Respiratory Agents

Sympathomimetics

Psychotherapeutic Agents

Analgesics and Anti-Inflammatory Drugs

Antidiabetic and Antiobesity Drugs

Dietary Supplements

Caffeine

Ethanol, Nicotine, and Cannabis

Performance Enhancing Substances

Filters